The application relates to the technical field of pharmaceutical preparations, in particular to a sustained-release preparation of
isopropyl inosine and a preparation method and application thereof, and the sustained-release preparation of
isopropyl inosine comprises a tablet core and a
coating film covering the tablet core; wherein the tablet core comprises the following components in percentage by
mass: 70%-74.35% of
isopropyl inosine, 20%-25% of a hydrophilic
gel matrix material, 5%-14.35% of a filling agent, 0.5%-2% of a disintegrating agent and 0.15%-0.5% of a
lubricant; the
coating film comprises the following components in percentage by
mass: 70%-75% of a film
control material, 10%-20% of a pore-forming agent and 10%-20% of a
plasticizer; the weight of the
coating film is 5%-8% of the weight of the tablet core. The application provides the sustained-release preparation of isopropyl inosine and a preparation method and application thereof; the sustained-release preparation of isopropyl inosine plays an anti-inflammatory and joint protection role by regulating T / B
lymphocyte activity and inhibiting inflammatory factor release, and makes up for the defects of traditional
arthritis treatment drugs, i.e. only relieving symptoms and being unable to regulate immune disorders.