The present application claims priority for Korean
patent application No. 10-2018-0072875 filed on June 25, 2018, the entire description of which is a reference for the present application. The present invention relates to a method for preparing
chondrocyte pellets, comprising the steps of: (a) culturing
human induced pluripotent stem cells so as to form and obtain embryoid bodies; (b) inducing the embryonic bodies obtained in step (a) to become outgrowth cells and isolating same; and (c) culturing the outgrowth cells isolated in step (b) in a pellet form. In addition, the present invention relates to: a pharmaceutical composition to be used in the treatment of
arthritis, comprising the
chondrocyte pellets prepared by the preparation method; or a method for preventing or treating
arthritis, comprising a step of administering the
chondrocyte pellets prepared by the method to an
arthritis patient.
Chondrocyte pellets of the present invention have a remarkably
high rate of differentiationinto chondrocytes, have a
uniform size, and have a homogeneous differentiation degree, and a pharmaceutical composition for treating arthritis, comprising same, has an excellent
cartilage regeneration effect when administered to the site of
cartilage damage, and is in an injectable form, which does not require
surgery, such that through a simple procedure, the pain of a patient is relieved and acontinuous arthritis
treatment effect can be provided even after the procedure.