A selective bidirectional regulation system of brain and body temperature in small animals

Abstract

The invention provides a selective brain-body temperature bidirectional regulation and control system for small animals, which is used for respectively regulate and control the temperatures of the brain and the body of a small animal. The selective brain-body temperature bidirectional regulation and control system comprises a body temperature regulation and control subsystem and a brain temperature regulation and control subsystem, wherein the body temperature regulation and control subsystem comprises a body supporting panel, four pillars, a first countercurrent exchange device, a dual-temperature independent-control temperature controller, two thermocouple temperature sensitive probes and a computer; the brain temperature regulation and control subsystem comprises a brain supporting panel, a second countercurrent exchange device, a drainage device, a water collection device, two connecting guide pipes, a normally-open solenoid valve, an intelligent temperature controller and a thermocouple temperature sensitive probe. The selective brain-body temperature bidirectional regulation and control system can realize differential temperature regulation and control, as well as bidirectional temperature regulation and control, of the brain and the body of the small animal, can quickly regulate and control to obtain the target temperature within 5-10 min, and can also achieve accurate temperature regulation and control within a target temperature permitted range.

Description

technical field [0001] The invention relates to the technical field of animal experiment equipment, in particular to a selective bidirectional control system for brain and body temperature of small animals. Background technique [0002] Keeping body temperature within the normal physiological range (such as about 36.5°C ± 0.5°C for humans) is an important condition for maintaining the homeostasis of the body's internal environment. Too high or too low temperature will cause permanent damage to tissues (such as hyperthermia and frostbite). On the other hand, some specific non-physiological temperature can also play a special therapeutic or protective role that is difficult to achieve at normal temperature. To achieve organ protection. Therefore, targeted temperature monitoring and moderate artificial temperature regulation are an important part of various clinical treatment programs, playing a main or auxiliary role. [0003] Taking hypothermia technology as an example, a l...

AI Technical Summary

Problems solved by technology

In previous studies, selective brain hypothermia was mostly achieved by spraying volatile liquids on the head surface of small animals or covering ice cubes. Disadvantages such as uneven speed and inability to realize two-way temperature regulation

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