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Rapid detection method for drugs on basis of handheld Raman spectrometer and handheld intermediate infrared spectrometer

A technology of Raman spectrometer and infrared spectrometer, which is applied in the field of rapid drug detection based on handheld Raman spectrometer and handheld mid-infrared spectrometer, which can solve the problems of short delivery time, low illegal cost, and complicated procedures, and meet the requirements of samples. The effect of small amount, guarantee of medication safety, and huge database

Inactive Publication Date: 2015-10-21
WUZHOU INST FOR FOOD & DRUG CONTROL
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  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the statutory laboratory inspection methods still have shortcomings such as time-consuming, cumbersome operations, and complicated procedures. Criminals take advantage of the advantages of modern logistics such as short delivery time, concealed means that are difficult to be discovered, and low illegal costs to evade, transfer, or even destroy. Create fraudulent acts to achieve the purpose of profit

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  • Rapid detection method for drugs on basis of handheld Raman spectrometer and handheld intermediate infrared spectrometer
  • Rapid detection method for drugs on basis of handheld Raman spectrometer and handheld intermediate infrared spectrometer
  • Rapid detection method for drugs on basis of handheld Raman spectrometer and handheld intermediate infrared spectrometer

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Embodiment 1

[0031] 1. Build a model

[0032] Establish the Raman spectrum model and mid-infrared spectrum model of multiple different drug samples; for the same drug sample, both the Raman model and the mid-infrared spectrum model can be established, and two models can be established at the same time, but its impact on the equipment Memory and processor requirements are slightly higher.

[0033] Preferably, the Raman spectrum model is established first, and if the Raman spectrum model cannot be established, then the mid-infrared spectrum model is established; this method can effectively reduce the number of models, and has practical significance in terms of equipment performance at the current stage.

[0034] 1.1. The handheld Raman spectrometer is equipped with 3 kinds of sample adapters. The unique sampling head can meet the requirements of non-contact and non-destructive sampling on the surface of various substances. It does not need to grind and destroy the samples. It can directly pa...

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Abstract

The invention discloses a rapid detection method for drugs on the basis of a handheld Raman spectrometer and a handheld intermediate infrared spectrometer. The rapid detection method comprises the following steps: step 1, establishing Raman spectral models and intermediate infrared spectral models of a plurality of different drug samples; step 2, respectively detecting the Raman spectrums and the intermediate infrared spectrums of to-be-detected samples by utilizing the handheld Raman spectrometer and the handheld intermediate infrared spectrometer; step 3, comparing the Raman spectrums with the Raman spectral models to determine the drug names of the to-be-detected samples according to characteristic peaks, and then comparing the intermediate infrared spectrums with the intermediate infrared spectral models to determine the drug names of the to-be-detected samples according to characteristic peaks. The rapid detection method for drugs on the basis of the handheld Raman spectrometer and the handheld intermediate infrared spectrometer, provided by the invention, can meet the on-site rapid detecting conditions of high portability, solidity, long continuous working time, automation in analysis and judgment, low operation cost, relatively high accuracy, and environmental friendliness.

Description

technical field [0001] The invention relates to the field of drug detection, in particular to a rapid drug detection method based on a hand-held Raman spectrometer and a hand-held mid-infrared spectrometer. Background technique [0002] After more than 30 years of rapid economic development through reform and opening up, my country's economic strength has surpassed that of Japan and has become the world's second largest economy. It has entered an era of economic transition and social transformation, showing a trend of high-tech and concealment of counterfeiting methods, drug safety Become a hot spot of social attention. In 2011, among the 10 typical cases of the crime of producing and selling counterfeit drugs nationwide, the value of each case exceeded 3 million yuan; in the daily supervision and random inspection of drugs in the region, more than 1,000 batches were unqualified. A series of incidents such as "Qi Er Yao" and "Exceeding the standard of chromium in capsules" a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/65G01N21/3563
Inventor 陈学松张涛刘慧妍罗达龙温志芳黄蘅张云平林昊林冬杰
Owner WUZHOU INST FOR FOOD & DRUG CONTROL
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