182 results about "Sample plane" patented technology

There is provided a microscopy device capable of (i) moving a liquid immersion objective lens to a location where liquid, such as an oil or water, can be applied to the liquid immersion objective lens, and (ii) moving the liquid immersion objective lens having liquid applied thereto to a sample holder, to be used to acquire images of a sample. The liquid application process can be automated so that the liquid on the objective lens is replenished as necessary. The device can automatically focus the lens to facilitate scanning, and can be configured to change objective lenses. Other embodiments, including using such a device in high content / high throughput scanning, are also described.

This application relates to the field of analytical chemistry detection technology, and in particular to a sample rack for a liquid chromatography-mass spectrometry (LC-MS) instrument used for TDM detection. The rack includes a support mechanism with a sample placement box at the top and a heat-insulating mechanism at the top. The invention utilizes components such as a pull-out plate, a spare support plate, and a table. The sliding engagement between the pull-out plate and the table allows for convenient horizontal sliding of the pull-out plate to retrieve and place samples placed in a first positioning slot. Simultaneously, the spare support plate is fixedly connected to a support side plate, enabling the categorized storage of samples after testing. These components work together to form an orderly sample management system, achieving the modular, partitioned design that efficiently distinguishes and quickly retrieves samples in different testing states, significantly improving the convenience and standardization of experimental operations.

The invention provides a sample table for a table type X-ray diffractometer, and relates to the field of diffractometers, the sample table comprises a sample rack, a sample table structure is inserted in the sample rack, the sample rack is provided with a lifting locking part used for limiting the sample table structure, the lifting locking part comprises a first T-shaped tube mounted at the bottom of the sample rack, and the first T-shaped tube is provided with a second T-shaped tube; a second T-shaped pipe is inserted into the bottom end of the first T-shaped pipe, a second T-shaped rod is connected to the second T-shaped pipe in a penetrating mode, a first T-shaped rod is connected to the top end of the second T-shaped rod, the top of the first T-shaped rod penetrates through the sample frame and extends into the sample frame, and the top of the first T-shaped rod makes contact with the bottom of the sample table structure. According to the sample table structure, the lifting locking part is arranged, the lifting locking part can complete locking of the sample table structure in a mode of rotating after lifting, the lifting locking part can complete unlocking action by moving downwards and resetting after rotating, operation is convenient and fast, use is facilitated, and the abrasion problem of traditional screw adjustment is avoided.

Systems and methods for automated cap removal with an autosampler system are described. In an aspect, an autosampler system includes, but is not limited to, a sample rack; a sample vessel stabilizer configured to transition the sample rack between a load / unload state and a lock state; an uncapper supported by a first z-axis support; and a sample probe supported by a second z-axis support, wherein the uncapper is configured to remove a cap from a sample vessel held by the sample rack when the sample rack is in the lock state, and wherein the uncapper is configured to change the position of the removed cap to permit access to an interior of the sample vessel by the sample probe without removing the sample vessel from the sample rack.

A system including a processor and a memory having instructions that, when executed by the processor, cause the system to obtain a point cloud of a turbine blade, the point cloud comprising data points corresponding to locations on an external contour of the turbine blade, generate an external mesh for the turbine blade based on the point cloud, define a reference axis along a length of the turbine blade, generate sampling planes along a length of the reference axis, each sampling plane being normal to the reference axis and having a shape defined by those portions of the external mesh intersecting the sampling plane, match each sampling plane to an airfoil profile in a database of known airfoil profiles, and create a geometrical representation of the turbine blade by placing the airfoil profiles on the reference axis and connecting the perimeter of each of the airfoil profiles.

The invention discloses a high-beam ion soft landing device based on a multistage difference technology, and belongs to the technical field of surface scientific sample preparation. The device comprises an electrospray ionization source, an ion transmission device, an ion deposition device and a sample transfer device which are connected in sequence. The ionization source couples high voltage to the solution through the spray needle fixing mechanism integrating the three-dimensional displacement table and the metal conductive connecting piece, and electrified micro-droplets are generated. The transmission device adopts a combination of a four-stage differential air exhaust cavity and a replaceable ion lens with a gradually increased aperture, so that efficient focusing and transmission of ions are realized, and desolvation is completed through a heating capillary tube. The deposition device drives a multi-clamping-groove vertical sample frame through a magnetic coupling sample transfer rod, and applies a deceleration electric field to a sample support by using an external bias power supply, so that ions are softly landed on a substrate with low kinetic energy. According to the invention, an expensive mass spectrum assembly is abandoned, and through linkage of all parts, high-flux and high-integrity clean deposition of macromolecules and heat-sensitive samples is realized while the cost is remarkably reduced.

The invention provides a linear scanning microscopic Raman spectrum imaging method and system, electronic equipment and a storage medium. The method comprises the following steps: obtaining Raman spectrums of the same sample in different directions; spectral feature maps are extracted from the Raman spectrums in different directions respectively; processing the spectral feature map to obtain reinforced features corresponding to different directions so as to make up that the spectral acquisition resolution in the line length direction is lower than the spectral acquisition resolution in the line width direction; and fusing the enhanced features to obtain a fused spectral feature map for qualitative or quantitative analysis. According to the invention, the uniformity of linear exciting light is improved by using a micro-cylindrical lens array or a DOE element, and an omnidirectional high-resolution spectral image in a sample plane is obtained by combining orthogonal double-frame sampling with an atlas fusion algorithm. The device is simple in structure and low in cost, linear exciting light energy spatial distribution uniformity and in-plane omnidirectional horizontal spatial resolution are improved, and a powerful tool is provided for rapid research of cell space metabolome.

A dynamic 3D light scattering particle size distribution measurement device includes a polarization splitter for generating an s laser beam with perpendicular polarization and a p laser beam with parallel polarization that travels parallel to and spaced apart from the s laser beam. A lens is used to focus the s laser beam and the p laser beam onto a common focus area inside a sample holder holding a sample whose particle size is to be measured. An s light intensity detector measures a time-resolved s light intensity from s backscattered light from the focus area. An s-polarisation filter allows perpendicularly polarized light to pass, resulting in s measuring light, and includes a light detector for time-resolved intensity measurements of the s measuring light. A p light intensity detector measures a time-resolved p light intensity detects p backscattered light from the focus area, and includes a p polarization filter that allows parallel polarized light to pass. A light detector provides for time-resolved intensity measurement of the p measuring light, and an evaluation unit automatically calculates the particle size distribution from the time-resolved p light intensity and the time-resolved s light intensity.

The present application relates to the technical field of liquid phase epitaxy growth of thin film materials, and particularly to a vertical liquid phase epitaxy graphite boat and a method for epitaxy using the same. The graphite boat comprises a sample holder, a stirring rod, a stirring base, and a crucible. The graphite boat can improve the uniformity of epitaxial materials, reduce surface defects, reduce the epitaxial composition and thickness difference caused by the inhomogeneity of the mother liquor, and avoid the melting of the surface layer of the substrate at high temperature in the mother liquor, which causes the change of the composition of the mother liquor. While ensuring the uniformity of the epitaxial thickness and composition, the epitaxial carbon contamination defects can be effectively reduced, and the batch yield can be effectively improved.

Techniques for measuring single synaptic signals under varying experimental conditions include controlling a video recording microscope to capture, at multiple different times, a first imaged area in a sample holder as a video frame when the sample holder is disposed on a stage and holds a sample of neuronal tissue combined with at least one fluorophore that emits a corresponding electromagnetic wavelength in a synapse during synaptic activity. At least one synaptic region of interest is determined based on a group of pixels in the first imaged area that record electromagnetic emissions from the fluorophore at the different times. An ordered time series of emission intensity is recorded in each of the synaptic region of interest. Peak emission intensity values in the time series are corrected for transmitter label transients. The ordered time series with corrected peak emission intensity values are stored in a data structure with a standard format.

The application discloses a confocal full Mueller matrix imaging device and method based on a fiber super surface array, and belongs to the technical field of polarized optical imaging. The device comprises a fiber array multi-polarization illumination module, a sample scanning module, a scattered light transmission module, a super surface array polarization modulation module and a polarized light intensity detection module. The polarization state of four beams of light is regulated by a fiber polarization controller, and four illumination focal spots with different polarization states are generated simultaneously on a sample plane. The sample scattered light is modulated by a polarization measurement super surface array comprising four independent super surface units, and the polarization state of each light signal is projected onto sixteen spatially separated polarized light spots. Finally, the light spot intensity information is collected by a surface array detector, and the full Mueller matrix image of the sample is reconstructed by calculation. The application realizes the acquisition of full Mueller matrix information in a single scan, has the characteristics of high resolution, compact structure and good compatibility, and can be used for multi-dimensional polarization microscopic analysis of samples.

The invention relates to an X-ray imaging apparatus (1) comprising: an X-ray source (2) generating an X-ray beam (F); a two-dimensional X-ray detector (3) comprising pixels (3a); a sample holder (4) configured to support a sample (E); at least one modulator (5), the at least one modulator (5) being a film on which a helical transmission modulation pattern is formed.

The application discloses a kind of multilayer sample pretreatment device and processing method, multilayer sample pretreatment device includes frame body, first shelf layer, second shelf layer and transfer unit, first shelf layer includes sequentially arranged several first warehouse storage sites, second shelf layer includes sequentially arranged code scanning position and several second warehouse storage sites, transfer unit is between code scanning position and second warehouse storage site, between first shelf layer and second shelf layer, second shelf layer and subsequent detection process, conveying unit between transfer sample frame.Sample pretreatment method, transfer unit preferentially transfers sample frame and test tube thereon between second shelf layer and subsequent detection process, recovery conveying unit.The application has reasonable structure, can adapt to large quantities of sample processing, conveying efficiency is high and degree of automation is high, and it is conducive to popularization and application.

The utility model relates to an arc-shaped sample rack compatible with sample tubes with different diameters, in particular to the technical field of medical instruments, which comprises a sample rack and a sample tube adapter, a plurality of mounting notches are arranged on the upper end face of the sample rack, and the sample tube adapter is used for mounting and limiting the sample tubes. A plurality of clamping jaws for limiting and guiding the sample tube are arranged in the sample tube adapter, a mounting reverse buckle is arranged on the sample tube adapter, and the sample tube adapter is connected with the sample rack through the mounting reverse buckle. According to the scheme, multiple groups of clamping jaws are matched, so that the sample tube adapter is compatible with multiple sample tubes, and meanwhile, the purposes that no gap exists between the sample tubes and the adapter, the sample tubes do not incline and the like can be achieved.

The utility model discloses an exposure device for an ozone in-vitro experiment. The exposure device comprises an experiment table, an exposure cabin and a contrast cabin, an extension plate is fixedly installed at the top end of the experiment table, electric telescopic rods are fixedly installed on the two sides of the extension plate in a penetrating mode, an upper cabin cover used for conducting attached sealing on openings in the upper ends of the exposure cabin and the contrast cabin is fixedly installed at the bottoms of the electric telescopic rods, and limiting sliding rods are fixedly installed on the two sides of the upper end of the upper cabin cover; an exhaust port is fixedly formed in the outer side of the upper cabin cover in a penetrating mode, an ozone catalytic decomposer used for decomposing ozone is fixedly installed on the rear side of the upper end of the experiment table, vertical limiting tables are fixedly installed on the inner sides of the exposure cabin and the contrast cabin, and the front ends of the vertical limiting tables are connected with sample frames in a magnetic attraction mode; a stainless steel grid for placing an experimental sample is fixedly mounted at the front end of the sample rack. The ozone contrast exposure experiment can be conveniently carried out through the exposure cabin and the contrast cabin, and the comparability of experiment conditions is ensured.

This invention discloses a porous sample holder for nano-ion probe analysis suitable for geological sample analysis. It includes a square sample holder body with multiple sample mounting holes, specifically three 1-inch circular holes, two 0.5-inch circular holes, and two 10-millimeter circular holes. The holes are spaced appropriately and equipped with limiting structures. The sample holder body is made of titanium alloy, possessing high strength, low weight, and excellent vacuum compatibility, meeting the needs of nano-ion probe analyzers for high-throughput, batch analysis of multiple samples. This sample holder has a reasonable structural design, is easy to load, and can effectively improve the efficiency of micro-area analysis of geological samples, showing promising application prospects.

A slide imaging device (110) for digital morphology in hematology is disclosed, comprising at least one z-axis stage (112) configured to place a microscope slide (114) at a sample plane, wherein a biological sample may be placed on the microscope slide (114), wherein the z-axis stage (112) is configured to set a relative distance along the optical axis (118) of the slide imaging device (110) between the microscope slide (114) and the imaging system (116) of the slide imaging device (110). The slide imaging apparatus (110) further includes at least one sample beam path and at least one autofocus beam path, the at least one autofocus beam path including at least one pattern illumination source (132), the at least one pattern illumination source including at least one light emitter (134) and at least one grating (136), wherein the grating (136) is tilted relative to the optical axis (118) of the slide imaging apparatus (110), wherein the autofocus beam path includes at least one second transmission system (140) and at least one autofocus camera (138), wherein the second transmission system (140) is configured to allow a pattern generated by the pattern illumination source (132) to be projected onto the sample plane and to allow a pattern reflected from the sample plane to be propagated to the autofocus camera (138), wherein the autofocus camera (138) is configured to generate at least one digital autofocus image of the pattern reflected from the sample plane. The slide imaging apparatus (110) further includes at least one processing unit (148) configured to analyze the digitally autofocused image, wherein the analysis includes spatial analysis of contrast and determination of the image location with maximum contrast. The slide imaging apparatus (110) further includes at least one control unit (150) configured to control the z-axis stage (112) taking into account the determined image location to position the microscope slide (114) along the optical axis (118) of the slide imaging apparatus (110).

The utility model discloses an in-situ XAFS multifunctional combination device which comprises a water-cooling shell and a heating sleeve, and a sample holder is mounted in the heating sleeve. A sample cavity is formed in the center of the sample frame, window pieces and window pressing pieces are arranged on the two sides of the sample cavity from inside to outside, and through holes corresponding to the light path through holes are formed in the heating sleeve and the sample frame; the other two sides of the sample holder are further connected with a gas path system, and the sample holder is further connected with a heating system. According to the invention, through careful adjustment and parameter control of the experimental environment, state reproduction of the reaction system in a real environment is ensured, an experimenter can conveniently obtain highly accurate experimental data with good repeatability, the reaction dead volume can be reduced, and the optical path can be shortened; according to the invention, not only are many technical bottlenecks of traditional equipment in a multi-phase reaction system solved, but also the experiment precision and the data credibility are greatly improved, and important technical support is provided for the research of a complex reaction system.

This utility model provides a low-pressure test chamber, comprising: a low-pressure test chamber body; a guide rod fixedly connected to the left side inside the low-pressure test chamber body; a sample rack installed in the center of the guide rod; a guide hole through the center of the left side of the sample rack, fitting the guide rod; the guide rod installed in the guide hole; a mounting groove on the right side of the sample rack; an internal height adjustment device installed in the mounting groove; a rotating rod installed on the right side of the sample rack; the top end of the rotating rod rotatably connected to the top of the inner wall of the low-pressure test chamber body; and an external height adjustment device installed at the bottom end of the rotating rod. This low-pressure test chamber, by incorporating the internal and external height adjustment devices, can quickly adjust the height of the sample rack and allows for external adjustment of the sample rack height.

The application relates to a teaching laser speckle interferometry experimental device for measuring material micro-morphology, belonging to the technical field of real-time diagnosis of material morphology of a tokamak wall. The device comprises a laser, a beam expander, a collimating mirror, a sample holder, two groups of beam splitters, a piezoelectric phase-shifting mirror, an imaging lens, a CCD camera and an optical platform. The device has a simple structure, the sensitivity can be dynamically expanded and selected according to actual detection conditions, and speckle interference fringes are obtained by subtracting the intensity field distribution functions before and after the surface displacement or deformation of the measured object. Compared with traditional morphology detection methods, physical contact with the measured object is reduced, thereby avoiding secondary deformation of the measured object and causing system errors.

Provided is an X-ray analysis system in which it is possible to readily move a sample between a sample conveyance mechanism and a holder receiver, while having a simple and compact configuration. The present invention is an X-ray analysis system including: a holder receiver; a sample conveyance mechanism in which a sample is disposed and that conveys the sample from a first position to a second position close to the holder receiver; a sample movement mechanism that moves the sample between the second position and a sample holding position; a first inclined part that is disposed between the second position and the holder receiver, that is provided in an end section on the first sample conveyance mechanism side, and that gradually becomes higher toward the holder receiver side; and a sample bridge that is provided on the holder receiver side of the first inclined part so as to be contiguous with the first inclined part and that is provided with a support part for supporting the sample. When the sample is pushed out to the holder receiver side, an end section of the sample on the sample holder side abuts on the first inclined part and then slides on the first inclined part to reach a first support part. Furthermore, when the sample is pushed out from a position on the first support part to the second position side, the end section of the sample is placed directly on the first sample conveyance mechanism.

A preparation method of metal-doped amorphous carbon film for flexible piezoresistive sensing, comprising the following steps: 1) installing and fixing a pure graphite target and a metal-graphite spliced target on two plane rectangular targets in a vacuum chamber of an octahedral structure thin film deposition device respectively, connecting the pure graphite target and the metal-graphite spliced target to the same positive and negative poles of a power supply, fixing a plurality of cleaned flexible substrates on corresponding positions arranged from top to bottom on a sample holder, and installing the sample holder on a revolution support of the vacuum chamber; 2) vacuumizing the vacuum chamber until the vacuum degree reaches 5*10 ‑4 Pa; 3) rotating the sample holder to the front of an ion source through the revolution support, and performing oxygen ion etching on the flexible substrate by adjusting oxygen ion etching parameters; 4) after the etching is completed, rotating the sample holder to the middle of the two plane rectangular targets through the revolution support, and depositing carbon ions and metal ions according to deposition parameters to form amorphous carbon films with different metal doping contents on each flexible substrate respectively.

An embodiment of the present invention relates to a subassembly for a sample compartment of a spectrometer. The subassembly includes a sample support adapted to support one or more sample holders for use in the sample compartment. The sample support is associated with one or more magnets. The subassembly further includes a sensor assembly configured to detect the one or more magnets associated with the sample support to identify a mode of operation of the spectrometer corresponding to the sample support.

A microsampling system includes a housing, a capillary fixed within a sealed internal environment defined by the housing, a robotic translation mechanism configured to support a sample holder and move the sample holder relative to the capillary in a plurality of directions, and a first port for connecting the sealed internal environment to a fluid source. A plurality of second ports may connect the sealed internal environment to a computing device, a voltage source, and / or a mass spectrometer ESI interface. A method of microsampling includes moving a sample holder within a sealed internal environment to operably position a capillary relative to a sample volume, pressurizing the sealed internal environment to inject a sample volume into the capillary, moving the sample holder to operably position the capillary relative to a BGE coupled to a voltage source, and applying electrical energy to separate the first sample volume via capillary electrophoresis.

Systems and methods for operating a cabinet irradiator. The methods comprise: receiving a sample holder in a receptacle of an XYZ stage platform of the cabinet irradiator (sample(s) is(are) disposed on the sample holder); controlling the XYZ stage platform to move the sample holder under a camera such that an optical axis is centered over a sample area of the sample holder; displaying a top-down image of the at least one sample in a first graphical user interface along with at least one virtual box having an adjustable size and being movable relative to the top-down image; receiving a user input specifying at least one area of the at least one sample that is to be irradiated via movement and or resizing of the at least one virtual box; receiving a user input selecting or defining an irradiation treatment plan; and irradiating the sample(s) in accordance with irradiation treatment plan.

Systems, methods, or techniques are provided for lamella lift-out based on sample plane orientation. In various embodiments, a method can comprise adjusting, by a scientific instrument, stage tilt and rotation of a sample stage of the scientific instrument based on plane orientation of a sample.

This invention discloses a fully automated sample pretreatment system for liquid addition, extraction, and filtration, belonging to the field of chemical analysis pretreatment technology. Addressing the problems of low efficiency, health risks, and information confusion associated with manual operation in existing technologies, this invention provides a solution, comprising: a first multi-dimensional robotic arm working in conjunction with a first scanning device to automatically scan, open, and add liquid to sample tubes; a second multi-dimensional robotic arm to move the sample rack, after liquid addition, into an ultrasonic water bath for extraction and then remove it; a three-axis moving mechanism integrating a third gripper and a syringe clamping module to complete secondary scanning, opening, aspiration, filter installation, pressure filtration, and the coding, opening, and closing of glass vials; and a controller coordinating the collaborative work of all components. This invention is mainly used for sample pretreatment in chemical analysis laboratories, achieving full automation of the liquid addition, extraction, and filtration process, improving processing efficiency and sample information traceability.