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Antibacterial traditional Chinese medicine composition, preparing method of antibacterial traditional Chinese medicine composition and application of antibacterial traditional Chinese medicine composition

A technology of composition and traditional Chinese medicine, which is applied in the field of antibacterial Chinese medicine composition and its preparation, and can solve problems such as irritation, negative environmental impact, and potential safety hazards

Inactive Publication Date: 2015-11-25
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these preservatives all have certain defects: for example, DMDMH is easy to release methanol during use, which has potential safety hazards; the Casson series will cause certain irritation to certain skin types during use because of its chlorine content; Er, it is easy to form carcinogenic nitrosamines; IPBC may lead to excessive intake of iodine by users; paraben esters are easy to accumulate in adipose tissue; It has been confirmed that it can show a certain ability to simulate the female hormone estrogen, which has adverse effects on human safety and physiological systems; triclosin has been proven to have negative effects on the environment

Method used

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  • Antibacterial traditional Chinese medicine composition, preparing method of antibacterial traditional Chinese medicine composition and application of antibacterial traditional Chinese medicine composition
  • Antibacterial traditional Chinese medicine composition, preparing method of antibacterial traditional Chinese medicine composition and application of antibacterial traditional Chinese medicine composition
  • Antibacterial traditional Chinese medicine composition, preparing method of antibacterial traditional Chinese medicine composition and application of antibacterial traditional Chinese medicine composition

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preparation example Construction

[0033] The present invention provides the preparation method of the antibacterial Chinese medicine composition described in above-mentioned technical scheme, comprises the following steps:

[0034] The perilla seed, patchouli and usnea are mixed and extracted by ethanol percolation to obtain an antibacterial traditional Chinese medicine composition.

[0035] Adopting the technical scheme of the embodiment of the invention can overcome the problems of heavy smell, less active ingredient retention, many impurities, narrow antibacterial spectrum and strong irritation of the traditional Chinese medicine extract prepared by the traditional preparation process.

[0036] In the embodiment of the present invention, a certain amount of perilla seeds, patchouli and usnea were uniformly mixed, and then extracted by ethanol percolation method to obtain an antibacterial traditional Chinese medicine composition.

[0037] In the present invention, the contents of the perilla seeds, patchouli...

Embodiment 1

[0064] Crush and mix 60g perilla seed, 20g patchouli and 20g usnea respectively, add 100g of water and grind to 60-200 mesh, and adjust the pH value to 5;

[0065] Add lipase until the enzyme activity is 10U / g, and perform enzymatic hydrolysis for 2 hours at a temperature of 40°C;

[0066] Add 2000g80wt% ethanol solution to carry out percolation extraction;

[0067] Extract by percolation for 24 hours, filter, and take the filtrate;

[0068] Concentrate under reduced pressure at low temperature to remove the solvent, replace it with glyceryl caprylate, and set the volume to 200g;

[0069] Aging at -10°C for 12 hours, filtering after stratification, and taking the supernatant to obtain the natural preservative extract (antibacterial traditional Chinese medicine composition).

Embodiment 2

[0071] Crush 80g perilla seed, 10g patchouli, and 10g usnea respectively, mix them evenly, add 100g of water and grind to 60-200 mesh, and adjust the pH value to 5;

[0072] Add lipase until the enzyme activity is 5 U / g, and perform enzymatic hydrolysis at 60°C for 1 hour;

[0073] Add 3000g of 95wt% ethanol solution for percolation extraction;

[0074] Extract by percolation for 24 hours, filter, and take the filtrate;

[0075] Concentrate under reduced pressure at low temperature to remove the solvent, replace it with caprylic capric glycerin, and set the volume to 200g;

[0076] Aging at -10°C for 12 hours, filtering after stratification, and taking the supernatant to obtain the natural preservative extract.

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Abstract

The invention provides an antibacterial traditional Chinese medicine composition, a preparing method of the antibacterial traditional Chinese medicine composition and application of the antibacterial traditional Chinese medicine composition. The antibacterial traditional Chinese medicine composition is prepared from raw materials including fructus perillae, patchouli and sunglow. Through reasonable matching application and synergistic effects of traditional Chinese medicine, the extracted composition has a broad-spectrum antibacterial effect, and is suitable for being used as natural preservatives. Experiments prove that singly for each bacterium of staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, candida albicans and aspergillus niger, the antibacterial effect of the matched composition is superior to the antibacterial effect of single plants; the result that the total effect of the composition is better than sum of the effects of two single plants is achieved; the synergistic effect of antibacterial effects among the plants is achieved. In addition, the composition provided by the invention has the characteristics that the flavor is small; the color is light; the mild effect is achieved; the solubleness is good; economy is realized; the consumption is low; the stability is high; the antibacterial traditional Chinese medicine composition is suitable for industrial production, and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an antibacterial traditional Chinese medicine composition and a preparation method and application thereof. Background technique [0002] Generally speaking, the concept of antibacterial can include sterilization, sterilization, bacteriostasis, mildew prevention and anticorrosion, etc. Antimicrobials, or preservatives, are substances that prevent the growth of microorganisms. In daily life, cosmetics are easily deteriorated by microbial contamination, which can be reflected in the appearance under normal circumstances. For example, mold and yeast often appear moldy spots on the edge of product packaging; products contaminated by microorganisms will appear turbidity, sedimentation, color change, pH value change, foaming, and odor, and if it is an emulsion, it may appear demulsification , into blocks, etc. Preservatives are added to cosmetics to protect prod...

Claims

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Application Information

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IPC IPC(8): A01N65/22A01P1/00A01P3/00A61K8/97A61K8/92A61K8/65A61K8/73A61Q19/00
CPCA61K8/65A61K8/73A61Q19/00A61K8/92A01N65/22C12Y301/01A61K8/9733A61K8/9767A61K8/9789A61P31/04A61P43/00A01N65/00C12P1/00
Inventor 邓文娟刘光荣
Owner INFINITUS (CHINA) CO LTD
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