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Bezoar brain refreshing tablet and preparation method thereof

A technology for Niuhuang and Nao tablets is applied in the field of preparation of Niuhuang Jingnao tablets, which can solve the problems of insufficient extraction of effective components, affecting the quality of material powder, poor drug efficacy, etc. The effect of shortening working hours

Inactive Publication Date: 2015-11-25
韩志强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the above-mentioned preparation method, the preparation of precious animal and plant medicinal powders such as pearls, bezoar, cinnabar, and borneol adopts common crushing technology, which affects the powder quality of the material. Other active ingredients are roughly processed after simple extraction, resulting in It cannot be fully extracted, the drug effect is not good, and the effect is slow

Method used

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  • Bezoar brain refreshing tablet and preparation method thereof
  • Bezoar brain refreshing tablet and preparation method thereof
  • Bezoar brain refreshing tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Prescription of Niuhuang Jingnao Tablets:

[0035]

[0036] Preparation:

[0037] (1) Pre-grind the bezoar, realgar, pig gall paste, pearl, cinnabar, borneol, calcined cassia, ochre, and calcined magnetite in the prescription, then mix them for ultrafine grinding, pass through a 300-mesh sieve, and granulate with a particle size of 20-30 μm , generally no more than 50 μm;

[0038] (2) Flash extraction of coptis

[0039] Crush the Coptidis rhizome of the prescribed amount into coarse powder, pass through a 40-mesh coarse sieve, add 10 times the amount of distilled water, and adjust the pH to 5.0 with vinegar, and place it in a flash extractor at room temperature with an extraction voltage of 120V and an extraction time of 5 minutes. Obtain the extract, concentrate to obtain the extract;

[0040] (3) Scutellaria baicalensis and rhubarb extracted by ultra-high pressure

[0041] Mix the raw materials of Scutellaria baicalensis and rhubarb in the prescribed amount and...

Embodiment 2

[0050] Prescription of Niuhuang Jingnao Tablets:

[0051]

[0052] Preparation:

[0053] (1) Pre-grind the bezoar, realgar, pig gall paste, pearl, cinnabar, borneol, calcined cassia, ochre, and calcined magnetite in the prescription, then mix them for ultrafine grinding, pass through a 300-mesh sieve, and granulate with a particle size of 20-30 μm , generally no more than 50 μm;

[0054] (2) Flash extraction of coptis

[0055] Grind the prescribed amount of Coptis chinensis into coarse powder, pass through a 40-mesh coarse sieve, add 8 times the amount of distilled water, and adjust the pH to 5.5 with vinegar, and place it in a flash extractor at room temperature with an extraction voltage of 150V and an extraction time of 6 minutes. Obtain the extract, concentrate to obtain the extract;

[0056] (3) Scutellaria baicalensis and rhubarb extracted by ultra-high pressure

[0057] After mixing the Scutellaria baicalensis and rhubarb raw materials of the prescribed amount, p...

Embodiment 3

[0066] Prescription of Niuhuang Jingnao Tablets:

[0067]

[0068] Preparation:

[0069] (1) Pre-grind the bezoar, realgar, pig gall paste, pearl, cinnabar, borneol, calcined cassia, ochre, and calcined magnetite in the prescription, then mix them for ultrafine grinding, pass through a 300-mesh sieve, and granulate with a particle size of 20-30 μm , generally no more than 50 μm;

[0070] (2) Flash extraction of coptis

[0071] Crush the Coptidis rhizome of the prescribed amount into coarse powder, pass through a 40-mesh coarse sieve, add 6 times the amount of distilled water, and adjust the pH to 5.8 with vinegar, and place it in a flash extractor at room temperature with an extraction voltage of 160V and an extraction time of 8 minutes. Obtain the extract, concentrate to obtain the extract;

[0072] (3) Scutellaria baicalensis and rhubarb extracted by ultra-high pressure

[0073] After mixing the Scutellaria baicalensis and rhubarb crude drugs of the prescribed amount,...

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Abstract

The invention discloses a preparation method of a bezoar brain refreshing tablet and the bezoar brain refreshing tablet prepared by the process. The bezoar brain refreshing tablet is characterized by being prepared by the following steps: respectively grinding bezoar and like traditional Chinese medicines by virtue of a superfine grinding technology to obtain superfine powder according to difference of various traditional Chinese medicines in nature; extracting coptis chinensis in a flashing mode; extracting scutellaria baicalensis and rheum officinale in a mode of ultrahigh pressure; extracting volatile oil from honeysuckle and the like in a supercritical mode; extracting cape jasmine fruit and like traditional Chinese medicines on the basis of continuous dynamic ethanol concentration; further concentrating extracted solutions so as to obtain an extract; mixing the extract and the volatile oil; adding accessory materials and preparing a soft material; and drying and tabletting so as to obtain the bezoar brain refreshing tablet. The preparation method disclosed by the invention optimizes the process of the preparation according to the natures of various medicines in the preparation; and compared with the prior art, the bezoar brain refreshing tablet prepared by the invention is high in content of active ingredients, low in content of impurities and significant in curative effect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a preparation method of Niuhuangjingnao Tablets and a prepared product. technical background [0002] Niuhuangjingnao tablet has the functions of clearing away heat and detoxification, calming the nerves. It is used for dizziness, mania, dizziness, and sore throat embolism caused by excessive heat. It is also used for internal heat, convulsions and convulsions in children. As a kind of Chinese patent medicine, Niuhuangjingnao Tablet has good clinical effect and has been accepted by the majority of patients. At present, the preparation of Niuhuangjingnao Tablet still adopts the method of Niuhuangjingnao Tablet recorded in the second volume of Chinese medicine preparations of the Ministry of Health. , honeysuckle, forsythia, skullcap, berberine, gypsum, dandelion, pearl, cinnabar, calcined cassia, calcined magnet, ocher, pig gall past...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/28A61P25/00A61P11/04A61K35/413A61K35/618A61K33/06A61K33/28A61K33/26A61K33/36A61K31/045
Inventor 韩志强
Owner 韩志强
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