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Oral medicine capable of effectively treating localized scleroderma and preparation method thereof

A technology for effective treatment of localized scleroderma, applied to medical preparations containing active ingredients, skin diseases, drug combinations, etc.

Inactive Publication Date: 2015-12-02
CHENGDU BEIJIATE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a kind of oral medicine that can effectively treat localized scleroderma and its preparation method, so as to solve the problem of early recovery of health of localized scleroderma patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Select 15 grams of high-quality and clean first-class Codonopsis pilosula, 9 grams of whole angelica, 9 grams of Chuanxiong, 30 grams of Astragalus, 15 grams of Atractylodes macrocephala, 9 grams of Fushen, 15 grams of longan meat, 9 grams of cassia twig, and 9 grams of polygala, and remove impurities and After dusting, put it into a cloth bag and tie it up for use; soak the medicines in cold boiled water for half an hour, then put the soaked medicines and the clarified solution of soaked medicines into the decoction machine, and inject 35mm of cold water into the decoction machine. Boil water for the first decoction for 40 minutes, filter the medicinal liquid, inject 30mm of medicine into lukewarm boiling water for the second decoction for 35 minutes, mix and concentrate into 1080 ml of 50% traditional Chinese medicine liquid, pack it in a bag and seal it for later use . When taking, the prepared Chinese medicinal liquid is divided into two days and taken, one dose per...

Embodiment 2

[0045] Select 16 grams of high-quality and clean first-class Codonopsis pilosula, 10 grams of whole angelica, 10 grams of Chuanxiong, 32 grams of Astragalus, 16 grams of Atractylodes macrocephala, 10 grams of Fushen, 16 grams of longan meat, 10 grams of cassia twig, and 10 grams of polygala, and remove impurities and After dusting, put it into a cloth bag and tie it up for use; soak the medicines in cold boiled water for half an hour, then put the soaked medicines and the clarified solution of soaked medicines into the decoction machine, and inject 35mm of cold water into the decoction machine. Boil water for the first decoction for 40 minutes, filter the medicinal liquid, inject 30mm of medicine into lukewarm water for the second decoction for 35 minutes, mix and concentrate to 1080ml of 50% traditional Chinese medicine liquid, pack in sealed bags for backup use. When taking, the prepared Chinese medicinal liquid is divided into two days and taken, one dose per day, once in t...

Embodiment 3

[0047] Select 15 grams of high-quality and clean first-class Codonopsis pilosula, 9 grams of whole angelica, 9 grams of Chuanxiong, 30 grams of Astragalus, 15 grams of Atractylodes macrocephala, 9 grams of Fushen, 15 grams of longan meat, 9 grams of cassia twig, and 9 grams of polygala, and remove impurities and After dusting, put it into a cloth bag and tie it up for use; put the medicines into cold boiled water and soak for half an hour, then put the soaked medicines and the clear solution of soaked medicines into the decoction machine, and inject 35mm of cold water Boil water for the first decoction for 40 minutes, filter the medicinal liquid, inject 30mm of medicine into lukewarm boiling water for the second decoction for 35 minutes, mix and concentrate into 1080 ml of 50% traditional Chinese medicine liquid, pack it in a bag and seal it for later use . When taking, the prepared Chinese medicinal liquid is divided into two days and taken, one dose per day, once in the morn...

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PUM

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Abstract

The invention relates to an oral medicine capable of effectively treating localized scleroderma and a preparation method thereof. The medicine is prepared from the following components in parts by mass: 1 to 3 parts of dangshen, 1 to 3 parts of root of angelica sinensis, 1 to 3 parts of ligusticum wallichii, 1 to 3 parts of astragalus membranaceus, 1 to 3 parts of rhizoma atractylodis macrocephalae, 1 to 3 parts of fushen, 1 to 3 parts of longan aril, 1 to 3 parts of cassia twig and 1 to 3 parts of polygala tenuifolia. The preparation method of the medicine comprises the following steps: choosing the high quality and clean first-level dangshen, root of angelica sinensis, ligusticum wallichii, astragalus membranaceus, rhizoma atractylodis macrocephalae, fushen, longan aril, 1cassia twig and polygala tenuifolia according to the parts by mass, respectively removing impurities and dust, then putting into a cloth bag and tying for later use; soaking the materials in cooled boiled water for half an hour, then putting the soaked medicine and supernatant liquid for soaking the medicine together into a drug-decocting machine, injecting cooled boiled water higher than the medicine by 35mm, decocting for 40 minutes for the first time, filtering to obtain medicine liquid, then injecting slightly warm boiled water higher than the medicine by 30mm, decocting for 35 minutes for the second time, mixing and concentrating to form 50 percent of 1080-milliliter traditional Chinese medicine liquid, bagging and sealing for later use.

Description

technical field [0001] The invention relates to the technical field of Chinese herbal medicines, in particular to an oral medicine that can effectively treat localized scleroderma, in particular to the field of oral medicine for localized scleroderma patients and a preparation method thereof. Background technique [0002] Localized scleroderma (LS), also known as morphea, is a disease characterized by localized skin and subcutaneous tissue fibrosis. The etiology is unknown, and it may be related to many factors. Its pathogenesis involves vascular alterations, immune system activation and dysregulation, fibroblast activation and fibrosis, associated with vascular endothelial cell damage, autoimmunity, microchimerism, transforming growth factor beta, connective tissue growth factor, insulin-like growth factor , matrix metalloproteinases and their tissue inhibitors, reactive oxygen species and so on. The disease lacks a unified condition assessment standard, and there is no s...

Claims

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Application Information

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IPC IPC(8): A61K36/77A61P17/00A61P19/04
Inventor 罗倩茹
Owner CHENGDU BEIJIATE BIOTECH
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