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A kind of application of amaranth extract

An extract and technology of Amaranthus amaranthus, which is applied in the field of new application of Amaranth amaranth extract, can solve the problems of high incidence, unreported anti-cancer effect of Amaranth amaranthus, and high mortality, and achieve good anticancer activity and inhibitory effect Obvious, simple and practical preparation process

Active Publication Date: 2019-02-05
KUNMING UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, so far, no research on the anticancer effect of Amaranth has been reported.
Cancer is a chronic disease with high morbidity and high mortality in today's society, and there is no drug report with a high cure rate

Method used

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  • A kind of application of amaranth extract
  • A kind of application of amaranth extract
  • A kind of application of amaranth extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1: the application of amaranth extract

[0021] 1. Preparation of Amaranth extract

[0022] (1) immerse 100 g of fresh Amaranthus rhizome in 200 g of ethanol solution with a mass percentage concentration of 95% for ultrasonic extraction, filter, add 200 g of ethanol solution to the filter residue for ultrasonic extraction for 30 minutes, repeat the extraction 3 times, and combine the filtrates to obtain the extract;

[0023] (2) The extract is distilled and concentrated under reduced pressure at 45°C and a vacuum of 0.05Mpa until it has no alcohol smell;

[0024] (3) Add distilled water to the concentrated extract according to the mass ratio of 1:1, mix evenly, add petroleum ether to the mixed solution for extraction according to the volume ratio of the mixed solution and petroleum ether at a ratio of 1:2, and collect Petroleum ether extract phase, repeated extraction 3 times, combined petroleum ether extract phase; reduced pressure distillation concentrated...

Embodiment 2

[0042] Embodiment 2: the application of amaranth extract

[0043] 1. Preparation of Amaranth extract

[0044] (1) immerse 100g of dried Amaranth branches and leaves in 500g of ethanol solution with a mass percentage concentration of 80% for ultrasonic extraction, filter, add 500g of ethanol solution to the filter residue for ultrasonic extraction for 60min, repeat the extraction twice, and combine the filtrates to obtain the extract;

[0045] (2) The extract is distilled and concentrated under reduced pressure at 43°C and a vacuum of 0.04Mpa until it has no alcohol smell;

[0046](3) Add distilled water to the concentrated extract according to the mass ratio of 1:2, mix evenly, add petroleum ether to the mixed solution for extraction according to the volume ratio of the mixed solution and petroleum ether at a ratio of 1:1, and collect The petroleum ether extract phase was extracted 4 times repeatedly, and the petroleum ether extract phases were combined; the petroleum ether e...

Embodiment 3

[0052] Embodiment 3: the application of amaranth extract

[0053] 1. Preparation of Amaranth extract

[0054] (1) immerse 100g of fresh Amaranthus rhizome and fruit in 300g mass percentage concentration of absolute ethanol solution for ultrasonic extraction, filter, add 300g of ethanol solution to the filter residue for ultrasonic extraction for 0.8h, repeat the extraction 4 times, and combine the filtrate to obtain the extract;

[0055] (2) The extract is distilled and concentrated under reduced pressure at 48°C and a vacuum of 0.05Mpa until it has no alcohol smell;

[0056] (3) Add distilled water to the concentrated extract according to the mass ratio of 1:1.5, mix evenly, add petroleum ether to the mixed solution according to the volume ratio of the mixed solution and petroleum ether at a ratio of 1:1.5 for extraction, and collect The petroleum ether extract phase was extracted repeatedly 3 times, and the petroleum ether extract phases were combined; the petroleum ether e...

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Abstract

The invention discloses application of an amaranthus spinosus extract in preparing anti-cancer drugs; amaranthus spinosus, as a conventional medicinal plant, has functions of clearing away heat and toxic materials, relieving swelling and pain, clearing liver and improving vision and the like; modern pharmacological researches show that the plant has pharmacological actions of analgesia and anti-inflammation, diuresis, abatement of fever, immunity, liver protection, blood glucose lowering, anti-malaria, anti-bacterium, anti-oxidation and the like; the inventor, in the process of searching for anti-tumor active ingredients of Chinese herbal medicines, discovers that the amaranthus spinosus extract has an excellent anti-tumor activity; and a preparation process of the amaranthus spinosus extract disclosed by the invention is simple and practical and the prepared extract is relatively good in anti-tumor activity, so as to lay a certain foundation for later researches on anti-cancer or adjuvant therapy effect of the plant extract.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a new application of amaranth extract. Background technique [0002] Amaranth (Amaranthus spinosus.L), also known as amaranth, amaranth, etc., is a plant in the family Amaranthaceae. It is distributed in most provinces of my country and Japan, India, Indochina Peninsula, Malaysia, Philippines, America and other places. It likes to grow in dry wasteland, and its habitat is in grass, riverside wasteland, wasteland, open land, hillside, etc. The young leaves of amaranth are used as wild vegetables among the people, and they are also used for detoxification and swelling, diuresis and pain relief, liver clearing and eyesight, dispersing wind and itching, killing insects and healing injuries. Studies have found that the plant contains free alkanes, sterols, flavonoids, triterpenoid saponins and other compounds. Modern pharmacological studies have shown that the plant ha...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/21A61P35/00
CPCY02A50/30
Inventor 冯阳陈军李拓潘卉赵扬
Owner KUNMING UNIV OF SCI & TECH