Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Solar dermatitis treating pharmaceutical composition and preparation method thereof

A technology of composition and medicine, which is applied in the field of pharmaceutical composition for treating solar dermatitis and its preparation, can solve the problems of inability to comprehensively prevent and treat solar dermatitis, skin organ damage, unsatisfactory, etc., and achieve better drug treatment effect , not easy to relapse, low side effects

Inactive Publication Date: 2016-01-13
临沂草之美医药科技有限公司
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of these drugs are hormonal drugs. Long-term use will not only cause certain damage to the skin or other organs, but also cannot fundamentally change the skin quality sensitive to sunlight.
In addition, there are a small amount of traditional Chinese medicine compositions used for the treatment of solar dermatitis, which have achieved therapeutic effects to varying degrees, but are not ideal
[0005] Chinese patent application 201410113112.8 discloses a traditional Chinese medicine composition for treating solar dermatitis, which is prepared from the following raw materials in parts by weight: 10-50 parts of purslane, 10-20 parts of notopterygium, 5-20 parts of Sophora japonica 5-15 parts of Scutellaria baicalensis, 5-10 parts of rehmannia glutinosa, 5-15 parts of lily, 5-15 parts of honeysuckle, 1-10 parts of dandelion, 5-15 parts of wolfberry, 9-15 parts of Scutellaria barbata, 9-15 parts of Chuanxiong 5-15 parts of Angelica dahurica, 0.2-9 parts of berberine, 5.5-15 parts of white peony, 6-9 parts of dried ginger, and 10-15 parts of licorice. , but it cannot comprehensively prevent and treat solar dermatitis

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Solar dermatitis treating pharmaceutical composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] The raw materials were weighed according to the following parts by weight: 5 parts of Caulis Spatholobus, 10 parts of Rehmannia glutinosa, 4 parts of chrysanthemum, 4 parts of dandelion, 5 parts of white fresh skin, 3 parts of Houttuynia cordata, 8 parts of red peony, 3 parts of honeysuckle, gardenia 4 parts of Rhizoma chinensis, 4 parts of Notopterygium, 5 parts of Scutellaria baicalensis, 9 parts of Chuanxiong, 4 parts of Angelica dahurica, 4 parts of Schizonepeta, 4 parts of Fangfeng, 5 parts of Sophora flavescens, 3 parts of Scrophulariaceae and 8 parts of licorice.

[0048] The preparation method is as follows:

[0049] (1): Take Mildew Spatholobus, wash away impurities, crush after drying, pass through a 100-mesh sieve, add 3 times the total weight of Mildew Spatholobus powder, and add ethanol with a volume fraction of 75%, and then add the total amount of Mildew Spatholobus powder 0.8% cellulase, leaching at 38°C for 1 hour, then reflux extraction at 65°C for 1 h...

Embodiment 2

[0053] The raw materials were weighed according to the following parts by weight: 15 parts of Caulis Spatholobus, 16 parts of Rehmannia glutinosa, 10 parts of chrysanthemum, 10 parts of dandelion, 9 parts of white fresh skin, 6 parts of Houttuynia cordata, 12 parts of red peony, 9 parts of honeysuckle, gardenia 8 parts of Chinese herb, 8 parts of Notopterygium, 17 parts of Scutellaria baicalensis, 15 parts of Chuanxiong, 14 parts of Angelica dahurica, 9 parts of Schizonepeta, 12 parts of Fangfeng, 10 parts of Sophora flavescens, 6 parts of Scrophulariaceae and 16 parts of licorice.

[0054] The preparation method is as follows:

[0055] (1): Take Mildew Spatholobus, wash away impurities, crush after drying, pass through a 120-mesh sieve, add 80% ethanol in an amount 4 times the total weight of Mildew Spatholobus, then add the total amount of Mildew Spatholobus coarse powder 1.0% cellulase, leaching at 40°C for 1 hour, then reflux extraction at 70°C for 1 hour, filtering and re...

Embodiment 3

[0059] The raw materials were weighed according to the following parts by weight: 12 parts of Caulis Spatholobus, 14 parts of Rehmannia glutinosa, 6 parts of chrysanthemum, 8 parts of dandelion, 7 parts of white fresh skin, 5 parts of Houttuynia cordata, 10 parts of red peony, 6 parts of honeysuckle, gardenia 6 parts of Chinese herb, 6 parts of Notopterygium, 13 parts of Scutellaria baicalensis, 12 parts of Chuanxiong, 10 parts of Angelica dahurica, 6 parts of Schizonepeta, 10 parts of Fangfeng, 6 parts of Sophora flavescens, 4 parts of Scrophulariaceae and 14 parts of licorice.

[0060] The preparation method is as follows:

[0061] (1): Take Mildew Spatholobus, wash away impurities, crush after drying, pass through a 140-mesh sieve, add 6 times the total weight of Mildew Spatholobus powder, and add ethanol with a volume fraction of 80%, and then add the total amount of Mildew Spatholobus powder 1.2% cellulase, leaching at 45°C for 2 hours, then reflux extraction at 75°C for ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a solar dermatitis treating pharmaceutical composition and a preparation method thereof and belongs to the technical field of traditional Chinese medicine. The pharmaceutical composition is prepared from suberect spatholobus stem, dried rehmannia root, chrysanthemum, dandelion, densefruit pittany root-bark, heartleaf gouttuymia gerb, radix paeoniae rubra, goneysuckle flower, cape jasmine fruit, rhizome or root of incised notopterygium, baical skullcap root, szechuan lovage rhizome, dahuricae angelica root, fineleaf schizonepeta herb, divaricate saposhnikovia root, light yellow sophora root, radix scrophulariae and radix glycyrrhiza. The pharmaceutical composition has efficacy of clearing heat and detoxicating, curing skin and protecting skin against allergy, dispersing stagnation and dredging the collaterals, reducing inflammation and relieving itching, clearing damp and rheumatism, and further has the advantages of good efficacy, low side effect, low recurrence rate, easiness in promotion and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a medicinal composition for treating solar dermatitis and a preparation method thereof. Background technique [0002] Solar dermatitis is a sun-related skin disease, commonly known as sunburn. It is an allergic skin disease caused by light that occurs in exposed areas. The principle is: normal skin is irradiated by ultraviolet rays to cause various cells in the dermis to release inflammatory mediators such as histamine, 5-hydroxytryptamine, and kinin, so that the blood vessels in the dermis expand and the permeability increases. In spring and summer, the active spectrum of this disease is mainly UVB. Normal skin is irradiated by ultraviolet rays to make various cells in the dermis release inflammatory mediators such as histamine, 5-hydroxytryptamine, and kinin, which causes the blood vessels in the dermis to expand and increase their permeabilit...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/808A61P17/00A61P37/08
CPCA61K36/232A61K36/236A61K36/237A61K36/238A61K36/287A61K36/288A61K36/355A61K36/484A61K36/486A61K36/489A61K36/538A61K36/539A61K36/65A61K36/71A61K36/744A61K36/75A61K36/78A61K36/804A61K36/808A61K2236/19A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 李晓明刘谦
Owner 临沂草之美医药科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products