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Medicine composition for treating gastric mucosal lesion

A technology for gastric mucosal injury and composition, which is applied in the directions of drug combinations, antibacterial drugs, pharmaceutical formulations, etc., can solve the problems of high long-term recurrence rate, breeding of other diseases, large side effects, etc., achieves broad market prospects, and has no toxic and side effects. Effect

Active Publication Date: 2016-01-13
李毅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Simple western medicine treatment only focuses on inhibiting gastric acid secretion and protecting gastric mucosa. Although the short-term healing rate is good, the long-term recurrence rate is high, and most chemical drugs not only have the effect of treating diseases, but also stimulate the gastrointestinal tract. , make the original damaged gastrointestinal mucosa further damaged, side effects are large, long-term use can easily destroy the balance of the body, aggravate the condition, and may cause other diseases to breed

Method used

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  • Medicine composition for treating gastric mucosal lesion
  • Medicine composition for treating gastric mucosal lesion
  • Medicine composition for treating gastric mucosal lesion

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0025] Take the raw materials according to the following weight ratio:

[0026] Baiji 50g, Fritillaria 30g, Panax notoginseng 30g, Calcined oyster 20g, Red ginseng 10g

[0027] The preparation method is as follows:

[0028] a. Take Fritillaria japonicus, Panax notoginseng and red ginseng, grind them, pass through a 60-mesh sieve, add 8 times the amount of 70%-95% v / v ethanol to extract twice, each time for 1h, combine the extracts, and concentrate under reduced pressure to Extract, and collect the dregs, set aside.

[0029] b. Take Baiji and calcined oysters and combine them with the dregs of step a, add 10 times the amount of water to extract twice, each time for 1 hour, combine the extracts, concentrate under reduced pressure, add 50% v / v ethanol for precipitation, and take the supernatant The solution was concentrated under reduced pressure to an extract, and set aside;

[0030]...

Embodiment 2

[0032] The preparation of embodiment 2 pharmaceutical composition of the present invention

[0033] Take the raw materials according to the following weight ratio:

[0034] Baiji 42g, Fritillaria 22g, Panax notoginseng 22g, Calcined oyster 12g, Red ginseng 2g

[0035] The preparation method is as follows:

[0036] a. Take Fritillaria japonicus, Panax notoginseng and red ginseng, grind them, pass through a 60-mesh sieve, add 8 times the amount of 70%-95% v / v ethanol to extract twice, each time for 1h, combine the extracts, and concentrate under reduced pressure to Extract, and collect the dregs, set aside.

[0037] b. Take Baiji and calcined oysters and combine them with the dregs of step a, add 10 times the amount of water to extract twice, each time for 1 hour, combine the extracts, concentrate under reduced pressure, add 50% v / v ethanol for precipitation, and take the supernatant The solution was concentrated under reduced pressure to an extract, and set aside;

[0038] ...

Embodiment 3

[0040] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0041] Take the raw materials according to the following weight ratio:

[0042] Baiji 58g, Fritillaria 38g, Panax notoginseng 38g, Calcined oyster 28g, Red ginseng 18g

[0043] The preparation method is as follows:

[0044] a. Take Fritillaria japonicus, Panax notoginseng and red ginseng, grind them, pass through a 60-mesh sieve, add 8 times the amount of 70%-95% v / v ethanol to extract twice, each time for 1h, combine the extracts, and concentrate under reduced pressure to Extract, and collect the dregs, set aside.

[0045] b. Take Baiji and calcined oysters and combine them with the dregs of step a, add 10 times the amount of water to extract twice, each time for 1 hour, combine the extracts, concentrate under reduced pressure, add 50% v / v ethanol for precipitation, and take the supernatant The solution was concentrated under reduced pressure to an extract, and set aside;

[0046]...

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Abstract

The invention provides a medicine composition for treating gastric mucosal lesion. The medicine composition comprises preparations prepared from, by weight, 42-58 parts of rhizoma bletillae, 22-38 parts of thunberg fritillary bulbs, 22-38 parts of pseudo-ginseng, 12-28 parts of calcined oyster shells and 2-18 parts of red ginseng. The medicine composition is novel medicine for treating gastric mucosal lesion clinically, the novel medicine is efficient, safe, free of toxic or side effects and suitable for being taken for a long time, and wide market prospect is achieved.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating gastric mucosal injury, a preparation method and application thereof, and belongs to the field of medicines. Background technique [0002] Gastric mucosal injury is the main pathophysiological link leading to gastric ulcer and acute and chronic gastritis. At present, it is believed that the occurrence of its injury is closely related to the weakening or relative weakening of the gastric mucosal self-protection, that is, the imbalance of gastric mucosal aggressive factors and protective / defensive factors. In recent years, medical experts have found through a large number of investigations that only 47% of people between the ages of 20 and 40 have normal gastric mucosa, but this period is the period when the labor force is the strongest, and its impact on humans can be imagined. Therefore, gastric mucosal injury will become one of the main problems facing human health in the 21st century...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P1/04A61P1/00A61P31/04A61K35/618
Inventor 李毅
Owner 李毅
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