Coherent self-adaptive optical aberration correction system

A technology of adaptive optics and aberration correction, which is applied in optics, optical components, instruments, etc., can solve the problems of poor imaging quality of living cells and achieve the effect of fast speed and aberration correction

Inactive Publication Date: 2016-01-13
SHENZHEN UNIV
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[0003] Aiming at the defects of the prior art, the present invention provides a coherent adaptive optical aberration correction system, the purpose of which is to realize the coherence enhancement and coherence of the two beams of coherent light by adjus

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[0019] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0020] The invention provides a method and system for correcting coherent adaptive optical aberrations, aiming at solving the problem of imaging aberrations of deep tissue cells in vivo. It is especially suitable for in vivo microscopic imaging of deep biological cells.

[0021] An embodiment of the present invention provides a coherent adaptive optical aberration correction system, including:

[0022] Laser light source, used to generate laser, the laser wavelength is 633nm;

[0023] Neutral density filter (Neutraldensity filter, NDF), used to receive the laser and control the light intensity of...

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Abstract

The invention discloses a coherent self-adaptive optical aberration correction system. The system comprises a laser light source, a reflective mirror, a spatial light modulator, and a neutral density filter, a half-wave plate and a beam expanding lens that are sequentially disposed in an incident light path of the reflective mirror. The reflected light of the reflective mirror serves as incident light of the spatial light modulator, and an angle between the incident light and the reflected light of the spatial light modulator is controlled by means of the reflective mirror. The control over coherent emphasis and coherent weakening of two light beams, regulation and control on the phase position of one of the two light beams can be achieved, so aberration correction of a microscopic system is achieved. A reference light source needs not to be implanted in sample, and the aberration correction speed is fast, so the system is quite suitable for deep aberration correction imaging of an in vivo sample.

Description

technical field [0001] The invention belongs to the technical field of optical microscopic imaging, and more specifically relates to a coherent adaptive optical aberration correction system. Background technique [0002] We know that when performing in vivo imaging of biological cells, the system often introduces large aberrations due to the unevenness of the surface of the biological sample and the inhomogeneity of the refractive index distribution inside the sample, which eventually leads to poor image quality. At present, the existing aberration correction method is adaptive optics aberration correction, which is a traditional aberration correction method. It needs to implant a reference light source (usually a fluorescent material such as fluorescent beads) in a biological sample. Biological samples are more harmful and limit the application of this method to in vivo imaging. Contents of the invention [0003] Aiming at the defects of the prior art, the present invent...

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Application Information

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IPC IPC(8): G02B27/00
CPCG02B27/0025G02B27/0062G02B27/0068
Inventor 屈军乐严伟邵永红叶彤田蜜
Owner SHENZHEN UNIV
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