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Xiaotangling capsules and preparing method thereof

A technology of Xiaotangling and capsule, applied in the field of Xiaotangling capsule and its preparation, can solve the problems of unsatisfactory curative effect, low curative effect, slow disintegration and the like

Inactive Publication Date: 2016-02-24
HEILONGJIANG JIANGHENG PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The commercially available Xiaotangling Capsules have unsatisfactory curative effect due to the composition and process, and the preparation is prepared by traditional technology, which has the disadvantages of slow disintegration and low curative effect

Method used

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  • Xiaotangling capsules and preparing method thereof
  • Xiaotangling capsules and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Take 192g of agarwood, 96g of poria cocos, 19.2g of hemp seed, 30g of coptis, 490g of trichosanthemi, 88g of Eucommia, 512g of astragalus, 180g of salvia miltiorrhiza, 128g of medlar, 160g of sarcocarpus, crush them into 60 mesh coarse powder, and extract them by carbon dioxide supercritical extraction method , the extraction pressure is 24Mpa, the extraction temperature is 16°C, the separator pressure is 11Mpa, the separator temperature is 42°C, the separation time is 1.7 hours, the carbon dioxide flow rate is 26L per hour, and the extract is obtained; the extract is dried under reduced pressure at 62°C to obtain a dry paste; Add 150g of mannitol to the dry paste, and use a high-energy nano-impact mill to pulverize it into a mixed dry paste powder with a particle size of 200-300nm; take the mixed dry paste powder, 45g of microcrystalline cellulose, 45g of cross-linked polyvinylpyrrolidone, and cross-linked carboxymethyl fiber Sodium plain 35g, mixed evenly, wet granulat...

specific Embodiment 2

[0030] Take 192g of agarwood, 96g of poria cocos, 19.2g of hemp seed, 30g of coptis, 490g of trichosanthemi, 88g of Eucommia, 512g of astragalus, 180g of salvia miltiorrhiza, 128g of medlar, 160g of sarcocarpus, crush them into 60 mesh coarse powder, and extract them by carbon dioxide supercritical extraction method , the extraction pressure is 35Mpa, the extraction temperature is 43°C, the separator pressure is 19Mpa, the separator temperature is 58°C, the separation time is 3.3 hours, the carbon dioxide flow rate is 33L per hour, and the extract is obtained; the extract is dried under reduced pressure at 78°C to obtain a dry paste; Add 200g of mannitol to the dry paste, and use a high-energy nano-impact mill to pulverize it into a mixed dry paste powder with a particle size of 200-300nm; take the mixed dry paste powder, 55g of microcrystalline cellulose, 55g of cross-linked polyvinylpyrrolidone, and cross-linked carboxymethyl fiber Sodium plain 45g, mixed evenly, wet granulat...

Embodiment 3

[0032] Take 192g of agarwood, 96g of poria cocos, 19.2g of hemp seed, 30g of coptis, 490g of trichosanthemi, 88g of Eucommia, 512g of astragalus, 180g of salvia miltiorrhiza, 128g of medlar, 160g of sarcocarpus, crush them into 60 mesh coarse powder, and extract them by carbon dioxide supercritical extraction method , the extraction pressure is 30Mpa, the extraction temperature is 30°C, the separator pressure is 15Mpa, the separator temperature is 50°C, the separation time is 2.5 hours, the carbon dioxide flow rate is 30L per hour, and the extract is obtained; the extract is dried under reduced pressure at 70°C to obtain a dry paste; Add 175g of mannitol to the dry paste, and use a high-energy nano-impact mill to pulverize it into a mixed dry paste powder with a particle size of 200-300nm; take the mixed dry paste powder, 50g of microcrystalline cellulose, 50g of cross-linked polyvinylpyrrolidone, and cross-linked carboxymethyl fiber Sodium plain 40g, mix well, wet granulate wi...

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Abstract

The invention discloses xiaotangling capsules and a preparing method thereof. The preparing method is characterized in that 192 g of agilawood, 96 g of poria cocos, 19.2 g of hemp seeds, 30 g of coptis chinensis, 490 g of radices trichosanthis, 88 g of eucommia ulmoides, 512 g of radix astragali, 180 g of salvia miltiorrhiza, 128 g of fructus lycii and 160 g of flatstem milkvetch seeds are taken and extracted through a carbon dioxide supercritical extraction method, the extract is dried under reduced pressure and smashed into nanometer dry paste through high-energy nanometer impact grinding, and a functional auxiliary material is added to prepare the xiaotangling capsules. The disintegration time is remarkably shortened, the treatment effect is remarkably better than commercially available xiaotangling capsules, and a positive effect is achieved.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a Xiaotangling capsule and a preparation method thereof. Background technique [0002] Xiaotangling Capsule nourishes qi and nourishes yin, clears away heat and fire, nourishes kidney and reduces urination. For diabetes. The commercially available Xiaotangling Capsules have unsatisfactory curative effect due to the composition and process, and the preparation is prepared by traditional technology, which has the disadvantages of slow disintegration and low curative effect. Contents of the invention [0003] In order to overcome the above disadvantages, the present invention provides a Xiaotangling capsule with fast disintegration speed and high curative effect and a preparation method thereof. [0004] Invention embodiment is as follows: [0005] Take 192g of agarwood, 96g of poria cocos, 19.2g of hemp seed, 30g of coptis, 490g of trichosanthemi, 88g of Eucommia, 5...

Claims

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Application Information

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IPC IPC(8): A61K36/835A61K9/48A61P3/10
CPCA61K36/835A61K9/1652A61K36/076A61K36/428A61K36/46A61K36/481A61K36/537A61K36/60A61K36/718A61K36/815A61K47/10A61K47/12A61K47/32A61K47/36A61K47/38A61K2236/37A61K2236/51
Inventor 不公告发明人
Owner HEILONGJIANG JIANGHENG PHARMA TECH CO LTD
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