Refining and purification method of N-acylamino acid

Abstract

The invention belongs to the field of fine chemical industry, and particularly relates to a novel refining and purification method of N-acylamino acid. The method comprises the following steps that 1, the N-acylamino acid is synthesized through a conventional condensation reaction; 2, most of ethyl alcohol in liquid subjected to the condensation reaction is removed through vacuum distillation; 3, an organic phase is separated from a water phase through acidification, and by means of cooling, the N-acylamino acid and water are made to form dispersion liquid; 4, water in the dispersion liquid is removed through a diaphragm filter press, dispersing and washing are conducted through water of which the mass is equal to that of materials, filtration is conducted through a filter, dispersing and washing are repeatedly conducted in this way for 3-5 times, drying is conducted, and high-purity N-acylamino acid solid powder is obtained. According to the novel refining and purification method of the N-acylamino acid, the problems that in the prior art, the purification effect is poor, the efficiency is poor, products are prone to yellowing, and by-products can be produced through part products and solvent can be effectively solved.

Description

technical field [0001] The invention belongs to the field of fine chemical industry, and specifically relates to a new method for refining and purifying N-acyl amino acids. Background technique [0002] In recent years, amino acid series surfactants have attracted people's attention because of their safety, biodegradability and excellent surface activity. N-acyl amino acid is an anionic surfactant formed by condensation of lauric acid and cocoic acid with amino acids, and has been widely used in daily chemicals, such as cleansing cream, toothpaste and shaving cream. [0003] At present, the industrial production of N-acyl amino acids is through condensation reaction, acidification and liquid separation, and then neutralization to form salts. This method uses liquid separation and purification to purify N-acyl amino acids. The purification effect is poor, and the product contains a lot of impurities. Usually for To improve the purification effect, a second liquid separation ...

AI Technical Summary

Problems solved by technology

[0004] Aiming at the above problems, the present invention provides a new method for refining and purifying N-acyl amino acids, which can effectively solve the problem of poor purification effect, low efficiency, and easy-to-produce products in the prior art. Yellow and some products will form by-products with solvents, etc.