Cervical/vaginal cast-off cell self-harvesting device

A technique of exfoliating cells and vagina, applied in the direction of trocars, etc., can solve the problems of reduced sensitivity and low number of cells, and achieve the effect of improving sensitivity, small size, and volume can be sent

Active Publication Date: 2016-03-16
PEKING UNIV SHENZHEN HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing method is to simply apply the sampler to the solid filter paper and then discard the sampler, so that only a small amount of cells can be transferred to the filter paper, and 90% of the...

Method used

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  • Cervical/vaginal cast-off cell self-harvesting device
  • Cervical/vaginal cast-off cell self-harvesting device
  • Cervical/vaginal cast-off cell self-harvesting device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] See figure 1 with figure 2 The device for self-collecting cervicovaginal exfoliated cells includes a sample bottle 1 and a sampler 2 .

[0024] The sample bottle 1 includes a bottle cap 11, a bottle body 12 and a solid filter paper 13. The sample bottle 1 is made of medical non-toxic hard plastic or other hard materials. The wall thickness of the bottle body 12 is 1 mm, and the solid filter paper 13 is about 1 mm, the lower part of the bottle body 12 is set as a cone portion 121, the cone portion 121 is conical, the solid filter paper 13 profile is matched with the cone portion 121 and the lining is attached to the cone portion 121; the inner diameter of the bottle cap 11 is the same as that of the bottle body The outer diameter of the bottleneck of 12 coincides, and bottle cap 11 has internal thread, and the bottleneck outer wall of bottle body 12 has external thread, and bottle cap 11 is threadedly connected with bottle body 12.

[0025] The sampler 2 is a sampling...

Embodiment 2

[0029] See image 3 with Figure 4 , the difference from Example 1 is that the sample bottle 1 in this embodiment is square, the bottle cap 11 is square, the cone part 121 is flat tapered, the bottle cap 11 and the bottle body 12 are snap-fitted, other structural features and The method of use is the same as that of Embodiment 1, and will not be repeated in addition.

Embodiment 3

[0031] See Figure 5 , Figure 5The schematic diagram of the sampler 2 provided for the embodiment of the present invention is different from the sampler 2 in the embodiment 1 and the embodiment 2 in that the sampler 2 is a sampling rod, and the head 22 is set as a rod head, and the rod head 22 is an egg round.

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PUM

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Abstract

The invention discloses a cervical/vaginal cast-off cell self-harvesting device. The device comprises a sample bottle and a sampler. The sample bottle comprises a bottle cap, a bottle body and solid-state filter paper. A cone part is arranged on the inner lower portion of the bottle body, and the solid-state filter paper is matched with the cone part in appearance and attached to the cone part in a lining mode. After the sampler harvests cervical/vaginal cast-off cells, the sampler is placed inside the sample bottle, the head portion of the sampler is placed inside the cone part, and the head portion of the sampler makes tight contact with the periphery of the solid-state filter paper. By means of the cervical/vaginal cast-off cell self-harvesting device, the DNA/RNA of the harvested cells can be reserved to the maximum degree, hence, HPV detection sensibility is greatly improved, and the screening mode that 'cervical/vaginal cell self-sampling high-risk HPV detection is turned into cervical cancer preliminary screening' can be improved; in addition, the cervical/vaginal cast-off cell self-harvesting device can also be used for storing the DNA/RNA of the cells at an indoor temperature, the self-harvesting device is small in size and can be sent, and thus central detection is facilitated.

Description

technical field [0001] The invention relates to a device for self-collecting exfoliated cells of the human body, in particular to a device for self-collecting and preserving exfoliated cells of the cervix and vagina. Background technique [0002] Endometrial cervical cancer is caused by human papillomavirus (Human PapillomaVirus, HPV). It is the only cancer with a clear etiology, which seriously threatens women's lives. Large-scale population screening is the most important preventive measure. The high cost of screening and insufficient medical resources have seriously restricted the screening of the entire population. Especially in poor areas where medical resources are scarce, the contradictions are more prominent and need to be resolved urgently. We have explored new technologies for cervical cancer screening and established a program of "preliminary screening of cervical cancer by detection of high-risk HPV in self-collected cervical and vaginal cells". This new screeni...

Claims

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Application Information

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IPC IPC(8): A61B10/02
Inventor 吴瑞芳杜辉张礼婕林金丽
Owner PEKING UNIV SHENZHEN HOSPITAL
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