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Medicine composition for treating esophagus cancer at middle and late stages

A composition and technology for esophageal cancer, which can be used in drug combinations, active ingredients of heterocyclic compounds, anti-tumor drugs, etc., and can solve problems such as unsatisfactory curative effects

Inactive Publication Date: 2016-04-20
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine has a certain therapeutic effect, but the curative effect is not satisfactory

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1: Pharmaceutical composition for treating advanced esophageal cancer and its preparation method

[0035] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating middle-advanced esophageal cancer are: 7280g of Pitia japonica 4400g, 380g of mulberry furan C380g, 60g of isofennel coumarin;

[0036] Preparation:

[0037] (1) According to the ratio of raw materials, take Pitia japonica, Echinocarpus, Sangfuran C, and isoanescoumarin, mix well, use ethanol with a concentration of 31% by weight as a solvent, and extract by warm soaking at 33°C. The number of extractions 13 times, each extraction time is 18 hours, each solvent consumption is 34 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.17, and filters After that, the medicinal solution passes through the XDA-8 macroporous adsorption resin column,...

Embodiment 2

[0040] Example 2: Medicinal composition for treating advanced esophageal cancer and its preparation method

[0041] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating middle and advanced esophageal cancer are: 7260g Pitia chinensis prisma 4500g Sorfuran C360g Isofeniscoumarin 80g;

[0042] Preparation:

[0043] (1) According to the ratio of raw materials, take Pitia japonica, Echinocarpus, Sangfuran C, and isoanescoumarin, mix well, use ethanol with a concentration of 31% by weight as a solvent, and extract by warm soaking at 33°C. The number of extractions 13 times, each extraction time is 18 hours, each solvent consumption is 34 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.17, and filters After that, the medicinal solution passes through the XDA-8 macroporous adsorption resin column, and is first elute...

Embodiment 3

[0046] Embodiment 3: The pharmaceutical composition and its preparation method for the treatment of advanced esophageal cancer

[0047] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating middle and advanced esophageal cancer are: 7300g of Pitia japonica 4300g, 4300g of mulberry furan C390g, 50g of isofennel coumarin;

[0048] Preparation:

[0049] (1) According to the ratio of raw materials, take Pitia japonica, Echinocarpus, Sangfuran C, and isoanescoumarin, mix well, use ethanol with a concentration of 31% by weight as a solvent, and extract by warm soaking at 33°C. The number of extractions 13 times, each extraction time is 18 hours, each solvent consumption is 34 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.17, and filters After that, the medicinal solution passes through the XDA-8 macroporous ad...

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PUM

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Abstract

The invention discloses a medicine composition for treating esophagus cancer at middle and late stages and a preparation method thereof. The medicine composition is prepared from pittosporum trigonocarpum seeds, neotorularia humilis, mulberrofuran C and isopimpinellin and can be prepared into various dosage forms according to a conventional preparation process, and the curative effect on the esophagus cancer at middle and late stages is remarkable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating middle-advanced esophageal cancer and a preparation method thereof. Background technique [0002] Esophageal cancer belongs to the category of "choking diaphragm" disease in traditional Chinese medicine. "Lingshu. Evil Qi Viscera Disease Form" contains a description of "spleen pulse is slightly urgent, it is in the diaphragm, food and drink enter and then exit, and then fertilization ends", which is similar to the symptoms of this disease. In the Yuan Dynasty, Zhu Danxi said that "it is on the top, and it is close to the bottom of the throat...", and clearly pointed out the location of the lesion. Qing. Wu Jutong thought: "Generally, choking is due to half a hundred years of yang decline and yin knot." Yang deficiency is inevitable for aging, and yang deficiency and cold accumulation are important pathog...

Claims

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Application Information

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IPC IPC(8): A61K36/31A61P35/00A61K31/343A61K31/37
CPCA61K36/185A61K9/2031A61K9/2054A61K9/4858A61K31/343A61K31/37A61K36/31A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH