Pretreatment liquid manufacturing structure of tissue engineering micromodule
A pretreatment solution and tissue engineering technology, which is applied in the direction of biological material pretreatment, tissue cell/virus culture device, biomass post-treatment, etc., can solve the problems of ineffective proliferation and migration, and achieve the effect of increasing cell activity
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0053] Such as figure 1 , a pretreatment liquid manufacturing structure of tissue engineering micromodule, which comprises:
[0054] The first channel 14 is used to transport the cell solution;
[0055] The second channel 13 is used to transport the sheath fluid, and the first channel 14 and the second channel 13 are externally connected to a pressure source with adjustable pressure (usually a syringe pump or a vacuum pump, and a peristaltic pump is rarely used);
[0056] third channel 23;
[0057] Such as image 3 , 8 , the first channel 14 and the second channel 13 converge at one place (the third channel 23 is also connected to the junction), and at the junction, the pretreatment solution wrapped with the sheath fluid outside the cell solution is formed, from The third channel 23 flows out, and the intersection is a cavity 51, and the entrance of the first channel 14 at the cavity 51 is surrounded by the inner space of the cavity 51 ( Figure 8 The dotted line in the ...
Embodiment 2
[0065] Such as Figure 9 , the dotted line part is our cavity 51, as can be seen in the figure, in this embodiment, the exit of the cavity 51 and the first channel 14 is a smooth transition, in actual work, the sheath fluid is injected first, After the cavity is filled, the cell solution is injected again. In this embodiment, since the cavity 51 and the outlet of the first channel 14 are in a smooth transition, correspondingly, the caliber of the third channel 23 and the opening of the first channel 14 The caliber is the same, so after the cell solution is injected, it will be compressed by the sheath fluid to be thinner, so that it can be wrapped by the sheath fluid in the cavity to form a pretreatment solution, and the formed pretreatment solution flows out from the third channel 23, compared with Example 1 In the structure, the laminar flow structure of the pretreatment liquid needs to be adjusted for a period of time to maintain stability, forming a finer pretreatment liqu...
Embodiment 3
[0067] Such as Figure 5 In the first cross-sectional schematic diagram, in this embodiment, except for the same structure as in Embodiment 1, the cross-sections of the first channel 14, the second channel 13, and the third channel 23 are all circular;
[0068] The cross-sections of the first channel 14, the second channel 13, and the third channel 23 do not necessarily adopt the same shape, but can be a combination of different shapes, such as Figure 5 , the combination of different shapes can still form the structure of the pretreatment solution of the sodium alginate solution wrapping the cell solution, but the cross section is different, Figure 5 as followed:
[0069] The cross section of the third channel 23 is square, and the cross section of the first channel 14 is square;
[0070] The cross section of the third channel 23 is square, and the cross section of the first channel 14 is circular;
[0071] The cross section of the third channel 23 is circular, and the cr...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More