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Medicine composition for treating chronic hepatitis and preparing method thereof

A technology for chronic hepatitis and composition, which is applied in the field of traditional Chinese medicine composition for treating chronic hepatitis and its preparation field, can solve the problems of toxic and side effects, difficult to treat, strong infectivity and the like, and achieves the effects of less toxic and side effects and good curative effect.

Inactive Publication Date: 2016-05-25
JILIN ZIXIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many drugs for the treatment of chronic hepatitis, but it is difficult to treat due to drug resistance and side effects. There is no ideal drug for the treatment of this disease. Because chronic hepatitis is a common clinical disease, it is highly contagious and endangers the health of patients.

Method used

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  • Medicine composition for treating chronic hepatitis and preparing method thereof
  • Medicine composition for treating chronic hepatitis and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Made from the following raw materials in parts by weight: 30 parts of bupleurum, 30 parts of capillary, 30 parts of isatidis, 25 parts of schisandra, 5 parts of pig gall powder, and 20 parts of mung beans;

[0021] The preparation method of active substance of the present invention comprises the following steps:

[0022] (1) Weigh Bupleurum bupleurum powder in proportion, ethanol reflux extraction 2 times, 1 hour each time, add 4 times the amount of 60% ethanol for the first time, add 3 times the amount of 60% ethanol for the second time, filter under reduced pressure, and combine The filtrate was decompressed to recover ethanol to a paste, the extract was dissolved in an equivalent amount of n-butanol saturated water, and extracted 4 times with an equivalent amount of water-saturated n-butanol, the extracts were combined, and concentrated to obtain saikosaponin;

[0023] (2) Weighing capillary wormwood in proportion, using supercritical CO 2 Extraction, put it into th...

Embodiment 2

[0029] Made from the following raw materials in parts by weight:

[0030] 40 parts of Bupleurum, 40 parts of Yin Chen, 40 parts of Banlangen, 32.5 parts of Schisandra, 7.5 parts of pig gall powder, 25 parts of mung beans;

[0031] The preparation method of active substance of the present invention comprises the following steps:

[0032] (1) Weigh Bupleurum bupleurum powder in proportion, ethanol reflux extraction twice, 1 hour each time, add 6 times the amount of 70% ethanol for the first time, add 5 times the amount of 70% ethanol for the second time, filter under reduced pressure, and combine The filtrate was decompressed to recover ethanol to a paste, the extract was dissolved in an equivalent amount of n-butanol saturated water, and extracted 4 times with an equivalent amount of water-saturated n-butanol, the extracts were combined, and concentrated to obtain saikosaponin;

[0033] (2) Weighing capillary wormwood in proportion, using supercritical CO 2 Extraction, put it...

Embodiment 3

[0039] Made from the following raw materials in parts by weight:

[0040] 50 parts of bupleurum, 50 parts of capillary, 50 parts of isatidis, 40 parts of schisandra, 10 parts of pig gall powder, 30 parts of mung beans;

[0041] The preparation method of active substance of the present invention comprises the following steps:

[0042] (1) Weigh Bupleurum bupleurum powder in proportion, extract with ethanol reflux twice, each time for 1 hour, add 8 times the amount of 80% ethanol for the first time, add 6 times the amount of 80% ethanol for the second time, filter under reduced pressure, and combine The filtrate was decompressed to recover ethanol to a paste, the extract was dissolved in an equivalent amount of n-butanol saturated water, and extracted 4 times with an equivalent amount of water-saturated n-butanol, the extracts were combined, and concentrated to obtain saikosaponin;

[0043] (2) Weighing capillary wormwood in proportion, using supercritical CO 2 Extraction, put i...

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Abstract

The invention relates to a medicine composition for treating chronic hepatitis and a preparing method thereof, and belongs to the field of traditional Chinese medicines. The medicine composition comprises 30-50 parts of radix bupleuri, 30-50 parts of capillary wormwood herbs, 30-50 parts of isatis roots, 25-40 parts of the fruits of Chinese magnoliavine, 5-10 parts of pig gallbladder powder and 20-30 parts of mung beans. According to the medicine composition, the theory of traditional Chinese medicine is applied, the advanced treatment technology means is adopted, and the medicine composition is used for soothing the liver, regulating qi, invigorating the spleen, promoting digestion and treating chronic hepatitis, and has the advantages of being good in curative effect and small in toxic and side effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for soothing the liver and regulating qi, invigorating the spleen and eliminating food, and treating chronic hepatitis and a preparation method thereof. Background technique [0002] Chronic hepatitis is the most common frequently-occurring disease in my country. There are about 20 million patients with chronic hepatitis in my country, and 1.5 million new cases each year. About 200,000 people die from hepatitis and diseases caused by hepatitis (such as liver cirrhosis, severe hepatitis and liver cancer) every year. It is an infectious disease that seriously endangers people's health. Chronic hepatitis is inflammation of the liver caused by viruses, drugs, alcohol, autoimmunity, etc., or the original history of hepatitis B, C, D or HBsAg, and this time the symptoms and signs of hepatitis reappear due to the same pathogen An...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K36/57A61P1/16A61K35/413
CPCA61K36/233A61K35/413A61K36/195A61K36/282A61K36/315A61K36/48A61K36/57A61K36/79A61K2236/331A61K2236/333A61K2236/37A61K2236/39A61K2236/53
Inventor 李男男殷金龙郭春生鲁敏荣梓清
Owner JILIN ZIXIN PHARMA
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