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Pharmaceutical composition for treating depression and preparation method thereof

A technology for depression and a composition is applied in the field of pharmaceutical compositions for the treatment of depression and the field of preparation thereof, which can solve the problems of high drug price, easy recurrence, and large toxic and side effects, and achieve the effects of simple operation and broad application prospects.

Inactive Publication Date: 2016-06-15
ZHEJIANG STRONG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] For the treatment of depression, 5-hydroxytryptamine reuptake inhibitors, monoamine oxidase inhibitors, phenylpyrazine derivatives, 5-hydroxytryptamine-norepinephrine reuptake inhibitors, aminoketones, tricyclics, tetracyclines, etc. There are 7 types of antidepressants such as cyclopiazine azepines, but most of the synthetic antidepressants have defects such as narrow antidepressant spectrum, large toxic and side effects, high drug price and easy relapse

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A pharmaceutical composition for treating depression, in terms of the following weight ratio, each component and content are: 2 parts of Guizhi, 2 parts of dried ginger, 2 parts of Schisandra chinensis, 2 parts of Suanzaoren, 2 parts of Codonopsis pilosula, 1 part of Chinese yam , 0.5 parts of Inula, 1 part of Zhuru, 1 part of Gualou, 1.5 parts of Shouwu vine, 1.5 parts of Ophiopogon japonicus, 2 parts of Rehmannia glutinosa, 1.5 parts of Moutan bark, 0.5 parts of fried gardenia, 0.5 parts of light bamboo leaves, 0.2 parts Senna. The pharmaceutical composition for treating depression is made into oral liquid.

[0025] The preparation method of the above-mentioned pharmaceutical composition for the treatment of depression, comprising the following steps,

[0026] A. The above sixteen medicinal materials are decocted with water, the quality of the water added is 7 times the mass of the sixteen medicinal materials, decocted 3 times, the first decoction is 1.5h, the second...

Embodiment 2

[0030] A pharmaceutical composition for treating depression. In terms of the following weight ratio, each component and its content are: 10 parts of cassia twig, 10 parts of dried ginger, 10 parts of Schisandra chinensis, 8 parts of fried jujube seed, 8 parts of Codonopsis pilosula, 3 parts of Chinese yam, 2.5 parts of inula, 3 parts of bamboo, 3 parts of melon, 4 parts of Shouwu vine, 4 parts of Ophiopogon japonicus, 8 parts of rehmannia glutinosa, 4 parts of Moutan bark, 2.5 parts of fried gardenia, 2.5 parts of light bamboo leaves, 1.5 parts of senna leaves. The pharmaceutical composition for treating depression is made into capsules.

[0031] The preparation method of the above-mentioned pharmaceutical composition for the treatment of depression, comprising the following steps,

[0032] A. The above sixteen medicinal materials are decocted with water, the quality of the water added is 10 times the mass of the sixteen medicinal materials, decocted 3 times, the first decoct...

Embodiment 3

[0038] A pharmaceutical composition for treating depression, in the following weight ratio, each component and its content are, in the following weight ratio, each component and its content are, 8 parts of cassia twig, 8 parts of dried ginger, 8 parts of Schisandra, 6 parts of Suanzaoren, 6 parts of Codonopsis pilosula, 2 parts of Chinese yam, 1.5 parts of Inula, 2 parts of Zhuru, 2 parts of Gualou, 3 parts of Shouwu vine, 3 parts of Ophiopogon japonicus, 6 parts of Rehmannia glutinosa, 3 parts of Moutan bark , 2 parts fried gardenia, 2 parts light bamboo leaves, 1 part senna leaf. The pharmaceutical composition for treating depression is made into tablets.

[0039] The preparation method of the above-mentioned pharmaceutical composition for the treatment of depression, comprising the following steps,

[0040] A. The above sixteen medicinal materials are decocted with water, the quality of the water added is 8 times the mass of the sixteen medicinal materials, decocted 3 time...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating depression. The composition is composed of the following components in parts by weight: 2 to 10 parts of cassia twig, 2 to 10 parts of dry ginger, 2 to 10 parts of Chinese magnoliavine, 2 to 8 parts of spine date seed, 2 to 8 parts of codonopsis pilosula, 1 to 3 parts of Chinese yam, 0.5 to 2.5 parts of inula flower, 1 to 3 parts of bamboo shaving, 1 to 3 parts of trichosanthes kirilowii Maxim, 1.5 to 4 parts of vine of multiflower knotweed, 1.5 to 4 parts of radix ophiopogonis, 2 to 8 parts of rhizoma rehmanniae, 1.5 to 4 parts of peony tree bark, 0.5 to 2.5 parts of fried cape jasmine, 0.5 to 2.5 parts of lophatherum gracile, and 0.2 to 1.5 parts of folium sennae.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound treatment agent, in particular to a pharmaceutical composition for treating depression and a preparation method thereof. Background technique [0002] Depression is a common affective mental disorder. It is a disease characterized by persistent low mood or mood, lack of interest, slow thinking, anorexia, sexual dysfunction, sleep disturbance and other physical symptoms. It can be caused by various reasons, with significant and persistent depression as the main clinical feature, and the depression is not commensurate with the situation. In severe cases, suicidal thoughts and behaviors may appear. Most cases have a tendency to relapse, and most of each attack can be relieved, and some may have residual symptoms or become chronic. Traditional Chinese medicine believes that depression belongs to the category of depression syndrome, which is a kind of disease caused by emotional discomfort an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P25/24
CPCA61K9/0053A61K9/08A61K9/4866A61K36/28A61K36/344A61K36/428A61K36/482A61K36/54A61K36/57A61K36/704A61K36/71A61K36/725A61K36/744A61K36/79A61K36/804A61K36/8945A61K36/8968A61K36/899A61K36/9068A61K2236/51A61K2236/39A61K2236/53A61K2236/331A61K2300/00A61P25/24A61K36/48A61K36/65A61K36/70A61K36/64
Inventor 虞陆平王文成
Owner ZHEJIANG STRONG PHARMA CO LTD