Unlock instant, AI-driven research and patent intelligence for your innovation.

An integrated system of column chromatography and membrane filtration

An integrated system, column chromatography technology, applied in membrane technology, semi-permeable membrane separation, chemical instruments and methods, etc., can solve the problem of high cost, achieve the effect of saving cost, shortening process time, increasing processing capacity and speed

Active Publication Date: 2017-10-03
宁波艾纯生物科技有限公司
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This type of system only simply integrates several different modules through pipelines, and can only realize that all modules work in sequence according to the pipeline connection sequence, and the cost is relatively high

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • An integrated system of column chromatography and membrane filtration
  • An integrated system of column chromatography and membrane filtration
  • An integrated system of column chromatography and membrane filtration

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Such as figure 2 Shown are the flow connections where the mobile phase first passes through the membrane module for purification.

[0058] 1) Add the raw materials to be separated into the first liquid storage tank FR1-1, open the first liquid storage tank inlet valve IV1, the membrane module selection valve CV1, the first circuit outlet valve OV4, the first exhaust outlet valve OV6, The second exhaust outlet valve OV8 and the second circuit outlet valve OV9, the quantitative raw material liquid is drawn by the pump P1, and the sample is filtered through the membrane module MM1, the concentrated liquid enters the first liquid collection tank BT1, and the permeate enters the second liquid collection tank bt2.

[0059] 2) After the liquid in the liquid collection tank reaches a certain amount, close the inlet valve IV1-1 of the first liquid storage tank, open the inlet valve IV6 of the first liquid collection tank, and carry out further circulation, concentration and fi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a bioengineering product separation and purification device and particularly relates to a column chromatography and membrane filtration integration system. The column chromatography and membrane filtration integration system comprises a column chromatography unit and a membrane filtration unit, wherein the two units use one pump and one detector. By virtue of switching the valve, an operation mode of sequentially performing membrane filtration and column chromatography and an operation mode of sequentially performing column chromatography and membrane filtration are realized, switching of the valve can be controlled by virtue of a computer, and automatic and full-closed operation of the device is realized.

Description

technical field [0001] The invention relates to separation and purification equipment for bioengineering products, in particular to an integrated system of column chromatography and membrane filtration to achieve the purpose of high-efficiency separation and purification. Background technique [0002] Column chromatography is a unit operation often used in modern chemical engineering and biochemical separation processes. For protein mixtures with complex components (such as plasma and enzymes), it is difficult to separate the active components, the process is complex, time-consuming, the resolution is poor, and the efficiency is low. In the separation process, the complementary separation and purification mode of chromatography column and membrane filtration is usually used. [0003] Traditional separation and purification methods require manual switching in the stages of sample pretreatment, column chromatography purification, membrane filtration, etc., and have to be oper...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): B01D15/10B01D63/08B01D63/02B01D63/00
CPCB01D15/10B01D63/00B01D63/02B01D63/08
Inventor 李秀男陈超赵大伟苏志国
Owner 宁波艾纯生物科技有限公司