Naked mole rat microsatellite marker site, primer and application thereof

Abstract

The invention belongs to the field of biological technical detection, and particularly relates to a naked mole rat microsatellite marker site, a primer and application thereof. The number of the built naked mole rat microsatellite marker sites reaches 45; the naked mole rat microsatellite marker sites can be used for genetic polymorphism detection of naked mole rat colonies; firm foundation is laid for naked mole rat microsatellite polymorphism detection.

Description

technical field [0001] The invention belongs to the field of biotechnology detection, and in particular relates to naked mole rat microsatellite marker sites. The primers for the microsatellite marker sites lay a foundation for the identification of genetic polymorphisms in closed populations of naked mole rats. Background technique [0002] As a new type of experimental animal, the naked mole rat has received extensive international attention in recent years. It has been reported that 80% of the naked mole rats captured in the wild have a life span of more than 24 years. Even after the age of 16, the mortality rate has not increased significantly, and no cancer has been found. . Unlike most other mammals, there was no significant change in bone density in naked mole rats between the ages of 1 and 24. And during the period from 5 to 20 years old, the basic metabolism, gastrointestinal absorption, and body composition of naked mole rats did not change with age. The physiol...

AI Technical Summary

Problems solved by technology

However, there are few reports on the genetics of naked mole rats

So far, only 12 microsatellite loci have been reported in naked mole rats, which is far from meeting the needs of genetic polymorphism identification in naked mole rats

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