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Obstructive sleep respiratory disorder disease animal model preparation system

A technology of sleep-disordered breathing and animal models, which is applied in the field of medical experiments, can solve the problems of airway obstruction, inability to provide real and reliable evidence for treatment, and incomplete simulation of obstructive sleep-disordered breathing diseases, so as to improve understanding and treatment Effect

Active Publication Date: 2016-07-06
于兆衍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this model cannot completely simulate obstructive sleep-disordered breathing disease, that is, the model cannot simulate two important pathological factors: one is airway obstruction, and the other is negative inspiratory pressure.
Without these two factors, it is impossible to simulate the pathophysiological process of humans suffering from obstructive sleep-disordered breathing disease, so that it cannot provide a true and reliable basis for future treatment
[0004] No suitable animal modeling method has been found so far, which seriously restricts the understanding and treatment of obstructive sleep disordered breathing disease

Method used

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  • Obstructive sleep respiratory disorder disease animal model preparation system
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  • Obstructive sleep respiratory disorder disease animal model preparation system

Examples

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Embodiment

[0049] see Figure 1-Figure 3 As shown, this embodiment provides a system for preparing an animal model of obstructive sleep-disordered breathing; Figure 1-Figure 3 The first to third schematic diagrams of the system for preparing an animal model of obstructive sleep-disordered breathing provided in this example.

[0050] see Figure 1-Figure 3As shown, the obstructive sleep-disordered breathing animal model preparation system (hereinafter referred to as the model preparation system) provided in this embodiment includes a head mask 1 and a simulated container device 2 . The simulated container device 2 may be, for example, a piping system, a sealable container, or the like. The material of the simulated container device 2 can be plastic, glass, metal, etc., for example.

[0051] The first end of the simulated container device 2 communicates with the inside of the hood 1, and the corresponding second end of the simulated container device 2 is used to connect to the gas sour...

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Abstract

The invention relates to the technical field of medical experiment, in particular to an obstructive sleep respiratory disorder disease animal model preparation system. The obstructive sleep respiratory disorder disease animal model preparation system comprises a head cap and a simulation container device, wherein the first end of the simulation container device is communicated with the inside of the head cap; the corresponding second end of the simulation container device is used for connecting an air source; a first valve is arranged between the simulation container device and the air source; one end of the head cap is open; the head cap is used for externally sleeving on a target animal; the opening of the head cap can be connected with the neck part of the target animal in a sealed way; a pressure stabilization device is connected onto the simulation container device; the pressure stabilization device presets a pressure threshold value and is used for controlling the on-off state of an air path inside and outside the simulation container device. The invention aims at providing the obstructive sleep respiratory disorder disease animal model preparation system for improving the knowing and treatment on an obstructive sleep respiratory disorder disease.

Description

technical field [0001] The invention relates to the technical field of medical experiments, in particular to a system for preparing animal models of obstructive sleep-disordered breathing. Background technique [0002] With the development of social and economic conditions, the medical industry has gradually attracted widespread attention, and people have paid more and more attention to the research of sleep-related diseases. A large number of epidemiological statistics show that obstructive sleep-disordered breathing is a disease that affects human sleep quality and even physical health. Since the 1980s, scholars at home and abroad have been exploring and establishing animal models of this disease so that people can understand, study, and treat obstructive sleep-disordered breathing. [0003] In the prior art, animal models of intermittent hypoxia have been gradually applied since the 1990s; this type of model preparation system is to keep experimental animals in airtight c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D7/00
CPCA61D7/00
Inventor 于兆衍
Owner 于兆衍
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