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Standard extract of chemical components of fraxinus rhynchophylla hance seeds as well as preparation method thereof and application thereof

A technology for the chemical composition of the large-leaf white wax tree, which is applied in the field of medicine, and can solve the problems that the chemical composition and pharmacological activity of the big-leaf white wax tree seeds have not yet been reported.

Inactive Publication Date: 2016-07-13
NORTHWEST UNIV(CN)
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] In recent years, most of the researches on the chemical constituents and pharmacological effects of A. japonicus are on its bark, but the chemical constituents and pharmacological activities of the seeds of A. echinacea have not been reported yet.

Method used

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  • Standard extract of chemical components of fraxinus rhynchophylla hance seeds as well as preparation method thereof and application thereof
  • Standard extract of chemical components of fraxinus rhynchophylla hance seeds as well as preparation method thereof and application thereof
  • Standard extract of chemical components of fraxinus rhynchophylla hance seeds as well as preparation method thereof and application thereof

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Embodiment Construction

[0021] In order to make the objects and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0022] Such as figure 1 As shown, the embodiment of the present invention provides a kind of EtOH-Water extract of the standardization of the chemical composition of the seeds of Ashwagandha japonicus, comprising the composition of the following mass percentages:

[0023] Iridoid monoglycoside oleoside methyl ester (1) 2.25mg / g, iridoid monoglycoside oleoside p-hydroxyethyl ester (2) 2.93mg / g, iridoid diglycoside oleoside glucoside (3 ) 377.28mg / g, hydroxyiridoid monoglycoside oleoside methyl ester (4) 11.24mg / g, iridoid triglucoside (5) 330.96mg / g, iridoid diglucoside (6) 27.37mg / g, p-hydroxyethyl glucoside (7) 26.06mg / g.

[0024] In the emb...

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Abstract

The invention discloses standard extract of chemical components of fraxinus rhynchophylla hance seeds as well as a preparation method thereof and application thereof. The extract comprises the following components in percentage by mass: 2.25mg / g of iridoid monoside glucosinolate methyl ester, 2.93mg / g of iridoid monoside glucosinolate p-hydroxyl ethyl ester, 377.28mg / g of iridoid bisglycoside glucosinolate glucose ester, 11.24mg / g of hydroxyl iridoid monoside glucosinolate methyl ester, 330.96mg / g of iridoid triglucoside, 27.37mg / g of iridoid bisglucoside and 26.06mg / g of p-hydroxyl ethyl glucoside. The EtOH-Water extract obtained in the invention can be used for preparing drugs for preventing and treating liver injuries, so that the research blank is filled.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to an extract with standardized chemical components of the seeds of A. japonicus and its preparation method and application. Background technique [0002] Fraxinus rhynchophylla Hance, also known as Fraxinus rhynchophylla Hance, is also known as Fraxinus rhynchophylla Hance. It is a large deciduous tree of the genus Fraxinus rhynchophylla Hance. Its bark is taupe or dark gray. It is a good tree species for embankment protection, sand fixation and urban greening. It is mainly distributed in the Northeast and the provinces of the Yellow River Basin. In addition, it is also distributed in the Soviet Union and North Korea. Its root bark, Qinpi, is commonly used as a traditional Chinese medicine. It has the effects of clearing away heat and dampness, improving eyesight, and reducing astringency. Modern pharmacological studies have shown that Qinpi has anti-tumor, anti-diabetic, and li...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K31/7032A61P1/16
CPCA61K31/7032A61K31/7048A61K2300/00
Inventor 白乃生郭森刘庆超张云婷张丽白璐张鑫鑫田潇
Owner NORTHWEST UNIV(CN)
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