Probiotics fermentation traditional Chinese medicine composition for treating infantile fever as well as preparation method and application thereof

A technology for children's fever and composition, applied in the field of traditional Chinese medicine, can solve the problems of infants' physical function failure, leftovers from antibiotic use, abnormal organ development, etc., and achieve the effects of improving human intestinal environment, reducing intestinal burden, and having good taste.

Inactive Publication Date: 2016-07-13
SANZHU FUER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Drug treatment is divided into western medicine treatment and traditional Chinese medicine treatment. The medicines for western medicine treatment mainly include acetylsalicylic acid (aspirin), lysampirin, ibuprofen (ibuprofen), compound zinc cloth granules, compound aminopyrine , acetaminophen (paracetamol), adrenocortical hormone (dexamethasone), and analgin (disabled). Although the above-mentioned medicines for treating fever in children with western medicine are effective, they have adverse reactions such as gastrointestinal irritation in children. The problem left over from the use of antibiotics is serious, which can lead to flora imbalance. While eliminating bacteria, the normal flora of the human body is also killed, resulting in double infection, resulting in ineffective use of antibiotics and a high mortality rate. At the same time, the abuse of antibiotics can reduce The body's resistance to bacteria, that is, as the amount of antibiotics increases, people become dependent on antibiotics, and their own resistance to the environment decreases, which affects their health. If antibiotics are used improperly, it will cause damage to body organs and cause double damage , especially the abuse of antibiotics in children, will lead to abnormal development of various organs, and even lead to the baby's physical failure and death; the medicines for traditional Chinese medicine treatment mainly include Bupleurum injection and prescriptions prescribed by Chinese medicine (including decoction, lotion, enema, etc.) Among them, the published related patents of traditional Chinese medicine for treating fever in children include: a traditional Chinese medicine composition for treating fever in children and its preparation method and application (CN103191282), a traditional Chinese medicine composition for treating fever in children (CN104688882), Medicine for children with fever (CN105213864), a traditional Chinese medicine for treating children with fever (CN104998090), etc. The above-mentioned Chinese medicine preparations are all processed and produced according to traditional preparation methods, the process is simple, the utilization rate of raw materials is low, the taste is extremely poor, and the effect is slow. It brings great pain to children and seriously hinders the promotion of traditional Chinese medicine products.

Method used

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  • Probiotics fermentation traditional Chinese medicine composition for treating infantile fever as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1: Preparation of probiotic fermented Chinese medicine composition A for treating fever in children

[0035] Each pair of traditional Chinese medicine is made of the following medicinal materials: Nepeta 4g, Fangfeng 4g, Honeysuckle 9g, Forsythia 4g, Bupleurum 7g, Pueraria 6g, Perilla leaves 7g, Arctium 3g, Gypsum 12g, Scutellaria baicalensis 3g, Reed root 7g , bellflower 3g, Folium 9g, peppermint 4g, licorice 1g, the specific preparation method is as follows:

[0036] (1) Medicinal material treatment: add 12 times the weight of medicinal materials to gypsum, soak for 60 minutes, extract with high-pressure water at 115-121°C for 60 minutes, filter, and reserve the filtrate; add 12 times the weight of medicinal materials to mint, soak for 60 minutes, Extract with high-pressure water at 115°C for 30 minutes, filter, and use the filtrate for later use; add 12 times the weight of medicinal materials to the nepeta and perilla leaves, soak for 60 minutes, then distill...

Embodiment 2

[0040] Example 2: Preparation of probiotic fermented Chinese medicine composition B for treating fever in children

[0041] Each pair of traditional Chinese medicine is made of the following medicinal materials: Nepeta 4g, Fangfeng 10g, Honeysuckle 6g, Forsythia 15g, Bupleurum 6g, Pueraria 6g, Perilla leaf 10g, Arctium 3g, Gypsum 30g, Scutellaria baicalensis 10g, Reed root 7g , bellflower 10g, Folium 9g, peppermint 6g, licorice 5g, the specific preparation method is as follows:

[0042] (1) Medicinal material treatment: add 10 times the weight of medicinal materials to gypsum, soak for 60 minutes, extract with high-pressure water at 115°C for 60 minutes, filter, and use the filtrate for later use; add 10 times the weight of medicinal materials to mint, soak for 60 minutes, Extract with high-pressure water for 30 minutes, filter, and use the filtrate for later use; add water 10 times the weight of medicinal materials to nepeta and perilla leaves, soak for 60 minutes, then disti...

Embodiment 3

[0046] Example 3: Preparation of probiotic fermented Chinese medicine composition C for treating fever in children

[0047] Each pair of traditional Chinese medicine is made of the following medicinal materials: Nepeta 10g, Fangfeng 4g, Honeysuckle 15g, Forsythia 4g, Bupleurum 10g, Pueraria 6g, Perilla leaf 10g, Arctium 6g, Gypsum 12g, Scutellaria baicalensis 10g, Reed root 7g , bellflower 10g, Folium 12g, peppermint 3g, licorice 10g, the specific preparation method is as follows:

[0048] (1) Medicinal material treatment: Add 8 times the weight of medicinal materials to gypsum, soak for 40 minutes, extract with high-pressure water at 121°C for 50 minutes, filter, and use the filtrate for later use; add 8 times the weight of medicinal materials to mint, soak for 40 minutes, Extract with high-pressure water for 30 minutes, filter, and use the filtrate for later use; add 8 times the weight of medicinal materials to the nepeta and perilla leaves, soak for 40 minutes, then distill...

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Abstract

The invention discloses a probiotics fermentation traditional Chinese medicine composition for treating infantile fever as well as a preparation method and application thereof. The fermentation traditional Chinese medicine composition is prepared by performing water extraction or distillation on fineleaf schizonepeta herb, divaricate saposhnikovia root, honeysuckle flower, weeping forsythia capsule, Chinese thorowax root, kudzuvine root, perilla leaf, great burdock achene, gypsum, baical skullcap root, reed rhizome, platycodon root, indigowoad leaf, peppermint, and licorice root, and inoculating probiotics for fermentation. According to the preparation method disclosed by the invention, the medicinal materials are extracted by different processes, so that the utilization rate of the medicinal materials is improved. The fermentation traditional Chinese medicine composition prepared by the method disclosed by the invention can be used for treating infantile fever, regulating the balance of intestinal flora, and improving the gastrointestinal function. Experiments show that the fermentation traditional Chinese medicine composition disclosed by the invention is good in effect of treating the infantile fever, quick in response and good in mouthfeel, does not have toxic or side effects, and is safe in clinical medication.

Description

technical field [0001] The invention relates to a probiotic fermented traditional Chinese medicinal composition for treating fever in children and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Fever is the most common symptom in pediatrics. It is an important pathological process and clinical manifestation of febrile diseases. The normal body temperature of children is measured by axillary temperature of 36-37°C. According to the degree of temperature rise in children, fever can be divided into the following four types: Low fever (below 37.5-38°C), moderate heat (38-39°C), high heat (39-40°C) and ultra-high heat (above 40°C). [0003] Fever has both positive and negative effects on the human body. Fever within a certain limit is the physiological defense response of the human body against diseases. At this time, the number of white blood cells increases, the production of antibodies is active, t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P29/00A61P1/00A61K33/06
CPCA61K36/538A61K33/06A61K36/195A61K36/233A61K36/238A61K36/28A61K36/315A61K36/346A61K36/355A61K36/484A61K36/488A61K36/534A61K36/535A61K36/539A61K36/634A61K36/704A61K36/855A61K36/899A61K2236/19A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 吴炳新陆继臣甄宗武牛纪江孙筱林
Owner SANZHU FUER PHARMA
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