Real-time fusion of anatomical ultrasound information with radiation delivery information for radiation therapy
A technology of radiation therapy and radiation therapy system, which is applied in the fields of therapy, radiation therapy, ultrasound/sonic wave/infrasonic wave diagnosis, etc., and can solve problems such as OAR damage and incomplete dose coverage of tumors
Active Publication Date: 2019-03-26
KONINKLJIJKE PHILIPS NV
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Problems solved by technology
In other words, a challenge is to register dosimetry and anatomical information in a common coordinate system during delivery
The second challenge is to accurately measure motion in substantially real time so that adjustments can be made to correct for position and / or motion during delivery
In the absence of precise anatomical information in the common and external beam coordinates during delivery of radiation, incomplete dose coverage to the tumor and significant damage to the OAR may result
Method used
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[0038] refer to figure 1 , schematically illustrates an embodiment of real-time fusion of anatomical ultrasound information with a radiation delivery information system 10 configured for EBRT. The system is shown using a radiation therapy configuration for EBRT with EBRT device 12 directed at prostate 14 of subject 16 . The radiation therapy planning unit 18 images the subject and stores the planning images of the subject as part of the radiation therapy plan 20 . Planning images can be obtained from CT images, MR images, and the like. The planning images are used to construct a radiation therapy plan 20 that includes instructions for placing radiation delivery to the anatomy of the subject. The planning image can include internal or implant fiducials 22 that are present in the planning image and facilitate registration of the planning image to radiation delivery and real-time anatomical information.
[0039] The radiation therapy planning unit 18 maintains a radiation ther...
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A radiation therapy delivery system (10) comprising: an ultrasound imaging unit (26), a radiation therapy delivery mechanism (12, 56, 70, 88), a plurality of fiducials (22, 90) located inside the subject, an image A fusion unit (40) and a delivery assessment unit (38). The ultrasound imaging unit (26) includes a transducer (30) that emits ultrasound to image an anatomical portion of the subject (16) in real time in a first coordinate system. A radiation therapy delivery mechanism (12, 56, 70, 88) delivers an amount of therapeutic radiation in the anatomical portion of the subject in a second coordinate system. The fiducials (22, 90) include implants or transrectal ultrasound probes (80). An image fusion unit (40) registers the locations of the plurality of fiducials to at least one of the first and second coordinate systems and tracks the locations of the fiducials in real time. A delivery evaluation unit (38) identifies the location and amount of delivered therapeutic radiation relative to the real-time imaged anatomical portion of the subject.
Description
technical field [0001] The following generally relates to medical imaging and radiation therapy. The present invention is particularly suited for use in connection with real-time imaging of anatomical information using ultrasound and delivery of radiation therapy, and will be described with particular reference thereto. However, it should be understood that the present invention is also applicable to other use cases and is not necessarily limited to the applications described above. Background technique [0002] Radiation therapy is a procedure that uses radiation to treat a patient, often to kill or destroy harmful tissue, such as a tumor. Radiation therapy is applied to the subject's tissue to minimize radiation to healthy tissue. Healthy tissue may include organs at risk (OARs) such as the heart, liver, kidneys, urethra, rectum, bladder, etc., which may be in close proximity to or include unhealthy tissue. Precise placement of radiation during delivery is important to ...
Claims
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IPC IPC(8): A61N5/10A61B90/00
CPCA61N5/1038A61N5/1067A61N2005/1051A61N2005/1058A61N2005/1061A61B2090/3929A61B6/032A61B8/0833A61B8/4483A61B8/483A61N5/1039
Inventor S·巴拉特E·德赫甘马尔瓦斯特A·K·贾殷A·M·塔赫玛塞比马拉古奥施F·G·G·M·维尼翁
Owner KONINKLJIJKE PHILIPS NV