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Stable montelukast oral rapidly disintegrating film as well as preparation method and application thereof

An oral instant film and film-forming material technology, applied in the field of medicine, can solve the problems of low mechanical strength, low hardness of orally disintegrating tablets, difficulty in packaging and transportation of finished products, and achieve the effect of outstanding stability and high stability

Inactive Publication Date: 2016-08-24
天津康鸿医药科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Orally disintegrating tablets usually have low hardness and low mechanical strength, which brings difficulties to the packaging and transportation of finished products

Method used

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  • Stable montelukast oral rapidly disintegrating film as well as preparation method and application thereof
  • Stable montelukast oral rapidly disintegrating film as well as preparation method and application thereof
  • Stable montelukast oral rapidly disintegrating film as well as preparation method and application thereof

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Embodiment 1

[0038]

Embodiment 2

[0040]

Embodiment 3

[0042]

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Abstract

The invention belongs to the technical field of medicine, and in particular relates to a stable oral instant montelukast film and its preparation method and application, wherein the film-forming material is a mixture of sodium hydroxypropyl methylcellulose and polyvinyl alcohol in a certain proportion . The product has high stability and is suitable for large-scale industrial production.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an oral instant film with montelukast as an active ingredient, a preparation method and application thereof. Background technique [0002] Montelukast sodium is an oral leukotriene receptor antagonist developed by Merck & Co. (known as Merck in the United States and Canada) that specifically inhibits the cysteinyl leukotriene (CysLT1) receptor in the airways , so as to improve airway inflammation and effectively control asthma symptoms. Montelukast sodium is a non-hormonal anti-inflammatory drug, suitable for the prevention and long-term treatment of asthma and the treatment of allergic rhinitis in adults and children over 1 year old, with three different specifications. Leukotriene modulators are the only long-term control drugs that can be used alone in addition to inhaled hormones. They can be used as an alternative treatment drug for mild asthma and a combined t...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K31/404A61P11/06A61P11/02
Inventor 吴疆孙歆慧王成港邹美香刘欢刘钫王安宋爱丽
Owner 天津康鸿医药科技发展有限公司
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