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Application of semen astragali complanati in preparing nootropic drugs

A kind of technology of Fructus Sinensis and medicine, which is applied in the field of application of Fructus Sinensis or its extracts in the preparation of nootropic drugs or food, which can solve the problems of no nootropic, no dementia and other disease treatments, and achieve the effect of promoting learning and memory

Inactive Publication Date: 2016-08-24
NANJING HAIHENG MEDICINE SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] There is no report about its nootropic aspect in the prior art and literature, nor is there any record of its use in the treatment of diseases such as dementia

Method used

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  • Application of semen astragali complanati in preparing nootropic drugs
  • Application of semen astragali complanati in preparing nootropic drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Take 500g of Shayuanzi coarse powder, add petroleum ether and reflux twice, each time for 2h, add 4L of petroleum ether each time, combine the extracts to recover petroleum ether under reduced pressure, add 50% ethanol to the dregs, and heat reflux for 3 times, each time reflux Flow for 2 hours, the amount of solvent is 5L each time, combine the extracts, concentrate under reduced pressure, add water to stir and dilute, add to the treated 1kgHPD100 column, wash with water until the collected solution is colorless, and then elute with 60% ethanol until it is colorless Or very shallow, combined, concentrated and dried to obtain the extract. Among them, sarcoside is 14.6%, and the total flavonoid content is 65.0%.

Embodiment 2

[0030] Take 500g of Shayuanzi coarse powder, add petroleum ether for ultrasonication 2 times, 2 hours each time, add 4L petroleum ether each time, combine the extracts to recover petroleum ether under reduced pressure, add 60% ethanol to the dregs and heat reflux twice, reflux 2 hours each time , the amount of solvent is 4L each time, the extracts are combined, concentrated under reduced pressure, stirred and diluted with water, added to the treated 1kgHPD100 column, washed with water until the collected solution is colorless, and then eluted with 70% ethanol until colorless or very shallow, combined, concentrated and dried to obtain the extract. Among them, sarcoside is 12.8%, and the total flavonoid content is 63.9%.

Embodiment 3

[0032] Take 500g of Shayuanzi coarse powder, add petroleum ether and reflux twice, each time for 2h, add 4L of petroleum ether each time, combine the extracts to recover petroleum ether under reduced pressure, and add 50% ethanol to the dregs for ultrasonic extraction 3 times, each time 2h, the amount of solvent is 4L each time, combine the extracts, concentrate under reduced pressure, add water to stir and dilute, add to the treated 1kgHPD100 column, wash with water until the collected solution is colorless, and then elute with 60% ethanol until colorless or Very shallow, combined, concentrated and dried to obtain the extract. Among them, sarcoside is 14.1%, and the total flavonoid content is 64.8%.

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PUM

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Abstract

The invention relates to an application of semen astragali complanati or an extract thereof in preparing nootropic drugs or food. Experiments prove that the semen astragali complanati and the extract thereof, which have an activity of promoting learning memory, can serve as raw materials of the nootropic drugs and food; therefore, the semen astragali complanati and the extract thereof are suitable for preparing nootropic drugs or food.

Description

technical field [0001] The present invention relates to the application of Semen Cinnamon, in particular to the application of Semen Cinnamon or its extract in the preparation of nootropic medicine or food. Background technique [0002] Shayuanzi is the dry mature seed of the leguminous plant Astragalus complanatus R.Brown. In late autumn and early winter, when the fruit is ripe and has not yet cracked, the plants are harvested, dried in the sun, the seeds are planted, impurities are removed, and dried in the sun. This product is slightly kidney-shaped and slightly flat, 2-2.5mm long, 1.5-2mm wide, and about 1mm thick. The surface is smooth, brown-green or taupe, with a round hilum on one side of the edge. The quality is hard and not easy to break. Cotyledon 2, light yellow, radicle curved, about 1mm long. Odorless, light taste, beany smell when chewed. [0003] Sha Yuan is also known as Tong Tribulus, Sha Yuan Tribulus, Tong Sha Yuan and so on. Shayuanzi is a commonly...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61P25/28A61P25/00A23L1/29
Inventor 钱世祥
Owner NANJING HAIHENG MEDICINE SCI & TECH CO LTD