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Compound hirudo ultramicro decoction piece and preparation method thereof

A leech and ultra-micro technology, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, and medical raw materials derived from leeches/helminths, etc., can solve the problems of waste of medicinal material resources and low bioavailability, and achieve safe and reliable use. , good curative effect, enhance the effect of autoimmune function

Inactive Publication Date: 2016-08-24
RUIAN PULUO BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Due to the above-mentioned shortcomings of the prior art, the present invention proposes a compound leech ultramicro decoction piece and its preparation method, which can effectively solve the shortcomings of the prior art's low bioavailability and waste of medicinal material resources

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0054] The invention also discloses a preparation method of compound leech ultrafine decoction pieces, the specific steps are as follows:

[0055] 1) Pretreatment: drying the raw materials of traditional Chinese medicines to obtain dried raw materials of traditional Chinese medicines;

[0056]2) Coarse crushing: coarsely crushing the dried traditional Chinese medicine raw materials obtained in step 1) with a pulverizer with a 100-mesh sieve to obtain a coarse powder of more than 100 mesh;

[0057] 3) Ultrafine wall breaking: the coarse powder obtained in step 2) is pulverized to 130-250 μm by an ultrafine pulverizer to obtain a broken wall fine powder;

[0058] 4) Ball milling to break the wall: the fine powder obtained in step 3) is added to a horizontal disc airflow mill, the speed of the horizontal disc airflow mill is 40-50 rpm, and after 2-8 hours ball milling is broken, Obtain airflow crushing broken wall powder;

[0059] 5) Sterilization by breaking the wall: placing ...

Embodiment 1

[0061] 1) Pretreatment: Mix the raw materials of traditional Chinese medicine according to the following weight ratio: 85 parts of leech, 3 parts of cornus, 3 parts of centipede, 3 parts of Chuanxiong, 1 part of paeonol, 1 part of mopancao, 1 part of golden plum grass, 1 part of Gynostemma pentaphyllum, 1 part of medlar and 1 part of Mopancao are dried to obtain dry raw materials of traditional Chinese medicine;

[0062] 2) Coarse crushing: coarsely crushing the dried traditional Chinese medicine raw materials obtained in step 1) with a pulverizer with a 100-mesh sieve to obtain a coarse powder of more than 100 mesh;

[0063] 3) Ultrafine wall breaking: the coarse powder obtained in step 2) is pulverized to 130-250 μm by an ultrafine pulverizer to obtain a broken wall fine powder;

[0064] 4) Ball milling to break the wall: the fine powder obtained in step 3) is added to a horizontal disc airflow mill, the speed of the horizontal disc airflow mill is 40-50 rpm, and after 2-8 h...

Embodiment 2

[0067] 1) Pretreatment: Mix the raw materials of traditional Chinese medicine according to the following weight ratio: 95 parts of leech, 5 parts of cornus, 5 parts of centipede, 5 parts of Chuanxiong, 2 parts of paeonol, 2 parts of Mopancao, 2 parts of Xiaojinmeicao, and Gynostemma pentaphyllum 2 parts, 2 parts of Lycium barbarum, and 2 parts of Mopancao, dried to obtain the raw material of dried Chinese medicine;

[0068] 2) Coarse crushing: coarsely crushing the dried traditional Chinese medicine raw materials obtained in step 1) with a pulverizer with a 100-mesh sieve to obtain a coarse powder of more than 100 mesh;

[0069] 3) Ultrafine wall breaking: the coarse powder obtained in step 2) is pulverized to 130-250 μm by an ultrafine pulverizer to obtain a broken wall fine powder;

[0070] 4) Ball milling to break the wall: the fine powder obtained in step 3) is added to a horizontal disc airflow mill, the speed of the horizontal disc airflow mill is 40-50 rpm, and after 2-...

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PUM

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Abstract

The invention discloses a compound hirudo ultramicro decoction piece, which comprises hirudo, pulp of cornus, centipede and ligusticum wallichii. The invention also discloses a preparation method of the compound hirudo ultramicro decoction piece. The preparation method comprises the following steps: pretreatment, coarse crushing, ultramicro cell wall breaking, ball-mill cell wall breaking, and cell wall breaking and sterilization. Through effective combination and mutual supporting of medicines, the product is prepared scientifically and is endowed with effects of activating blood to resolve stasis, activating meridians to stop pain and expelling wind and removing cold. By nursing body internal environment, immunity is enhanced. The compound hirudo ultramicro decoction piece is safe and reliable to use, has a good curative effect, and is effectively used for treating stroke.

Description

technical field [0001] The invention relates to an ultrafine decoction piece of compound leech and a preparation method thereof. Background technique [0002] Leeches, commonly known as leeches and horse turtles, belong to the phylum Annelids, class Hirudophylum, order Hirudidae, and family Hirudoceae. They grow and reproduce in inland freshwater waters. They are traditional special medicinal aquatic animals in my country. Hinders blood coagulation, thus has anticoagulant effect. Its dry products are processed and used as medicine in traditional Chinese medicine, which has the effects of treating stroke, high blood pressure, clearing blood stasis, amenorrhea, and traumatic injuries. [0003] Traditional Chinese medicine decoction pieces are processed in a conventional way, the active ingredients of the medicinal materials are lost or cannot be fully released, the cell wall breaking rate is extremely low, the bioavailability is low, and medicinal material resources are wasted...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K36/40A61K9/14A61P9/10A61K35/62A61K35/64
Inventor 杨钟华
Owner RUIAN PULUO BIOTECH