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Jaundice detection method and device thereof

A detection method and technology for jaundice, applied in the field of jaundice detection, can solve the problems of inability to accurately reflect serum bilirubin concentration, inability to achieve continuous monitoring, unfavorable continuous monitoring and the like

Active Publication Date: 2016-09-21
SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI +1
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Problems solved by technology

[0006] These devices from Minolta, although very convenient to use in a single measurement, are not conducive to continuous monitoring, especially for infants who are treated with blue light in a phototherapy box, these devices proposed by Minolta cannot do continuous monitoring
Moreover, after receiving blue light therapy, although the bilirubin in the skin is significantly decomposed, it cannot accurately reflect the concentration of serum bilirubin. Usually, the concentration of bilirubin in the skin can be better after 12 hours after the end of the phototherapy. reflect the concentration of bilirubin in the blood

Method used

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  • Jaundice detection method and device thereof
  • Jaundice detection method and device thereof
  • Jaundice detection method and device thereof

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Embodiment Construction

[0041] Below, the jaundice detection method and its device of the present invention will be described in detail with reference to the accompanying drawings.

[0042] The principle of this method is as follows:

[0043] Photons are absorbed and scattered when they travel in human tissue. When light is irradiated into human tissue, some photons will change the original transmission path through multiple scattering, and finally exit the tissue surface; the other part of photons will be absorbed by the tissue during the propagation process. Due to the pulsation of the arterial blood, the degree of absorption of the part of the photons passing through the arterial blood will change periodically with the pulsation of the arterial blood: when the heart contracts, the arterial blood is pumped into the peripheral blood vessels, and the blood vessels relax. The photons absorbed by the blood increase, and the outgoing light intensity becomes weaker; when the heart relaxes, the blood flo...

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Abstract

A method for detecting jaundice using an AC portion and a DC portion of a PPG signal, the bilirubin concentration being calculated according to the following equation: as shown in the picture. The jaundice detection method of the present invention applies an optical detection technique of photoelectric volume pulse waveography (PPG) Neonatal jaundice concentration detection, remove the melanin, hemoglobin and pulse wave on the detection of bilirubin concentration, can be newborns (especially in the phototherapy of newborns) to implement real-time, continuous monitoring.

Description

technical field [0001] The invention relates to jaundice detection, in particular to a method and device for jaundice detection. Background technique [0002] Jaundice is the most common clinical symptom in the neonatal period. The bilirubin produced by the decomposition of hemoglobin in red blood cells has not been eliminated from the living body due to some obstacles, and the concentration of bilirubin in the blood increases, which causes mental and developmental disorders. Sequelae of brain injury, including cerebral palsy, delayed development of motor function, audiovisual impairment, etc., is one of the important disabling factors in our country at present. According to statistics from the American Academy of Pediatrics (AAP), about 60% of newborns may have jaundice in varying degrees, and about 10% of newborns with jaundice need timely treatment. For the most severe form of kernicterus, the best available evidence suggests that at least 10% of confirmed infants will d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00
CPCA61B5/0059A61B5/0082A61B5/443A61B5/6803A61B5/6832A61B2503/04A61B2503/045
Inventor 张龙韩坤王沛沛石金龙胡敏露高静王卫东武晓东
Owner SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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