Method and apparatus for obtaining values of characteristic quantification parameters of fibrosis

Abstract

Embodiments of the invention provide a method and an apparatus for obtaining values of characteristic quantification parameters of fibrosis. A detection sample image of a biological slice is analyzed by taking a characteristic database as a unified objective standard, the values, capable of describing causes of the fibrosis of the biological slice, of the characteristic quantification parameters are output, the characteristic quantification parameters obtained through large amounts of data verification are parameters remarkably influenced by the causes of the fibrosis, and different values of the characteristic quantification parameters can reflect different causes of the fibrosis, so that a pathologist can assess the causes of the fibrosis according to the values of the characteristic quantification parameters, the assessment difference of the causes of the fibrosis caused by individual difference of pathologists is avoided, and the adverse influence of a dye on the biological slice in a conventional method is avoided.

Description

technical field [0001] The present invention relates to the technical field of image processing, in particular to a method and device for obtaining the value of a fibrosis characteristic quantification parameter. Background technique [0002] Biological tissue fibrosis is caused by many chronic diseases, which will seriously harm the lesions, such as liver, lung and other organs. The fibrosis of biological tissue is mainly reflected indirectly by the content and specific morphological characteristics of specific types of collagen in the extracellular matrix (Extracellular Cell Matrix, ECM). Taking liver fibrosis as an example, there are many causes of liver fibrosis, such as viral hepatitis, alcoholic fatty liver, liver cirrhosis caused by abnormal metabolism, etc. For liver fibrosis caused by different etiologies, different drugs need to be targeted for treatment. If the etiology of fibrosis is uncertain, multiple drugs are used directly to treat fibrosis, which not only ...

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Problems solved by technology

[0004] The above method of analyzing the etiology of liver fibrosis mainly depends on the subjective judgment of pathologists. Due to the individual differences in ability and experience among different pathologists, the etiology of fibrosis evaluated is not the same, sometimes Estimated etiology varies greatly, and is affected by the dye of the patient's liver tissue section, which may also lead to incorrect etiology assessed by the pathologist

At present, there is no method in the prior art that can provide pathologists with the values ​​of the characteristic quantification parameters of fibrosis that can reflect the etiology of fibrosis, so that pathologists can determine Efficient assessment of etiology leading to liver fibrosis

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