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Phosphorous reducing osteoprastics and preparing method thereof

A bone-replenishing medicine and phosphorus-lowering technology, which is applied in the fields of medical formula, bone disease, drug combination, etc., can solve the problems of many side effects, elevated blood calcium, and increased calcium-phosphorus product, achieving good preventive and therapeutic effects with few side effects , cheap effect

Inactive Publication Date: 2016-10-12
张春花
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Existing phosphorus binders such as calcium carbonate contain 40% calcium, and calcium acetate contains 25% calcium. These two phosphorus binders increase blood calcium while reducing phosphorus, and increase the calcium-phosphorus product, which is not conducive to secondary thyroid disease. Control of hyperparathyroidism; lanthanum carbonate, mostly imported or a Sino-foreign joint venture, is expensive and cannot be used by the public; cinacalcet, high cost, with many side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A bone-reducing medicine for reducing phosphorus, made from the following raw materials:

[0037] Rehmannia glutinosa 3kg, astragalus 7kg, yam 8kg, curculigo 25kg, epimedium 15kg, Atractylodes macrocephala 7kg, sea octopus 12kg, salvia miltiorrhiza 8kg, angelica 6kg, calcined oyster 35kg.

[0038] Its preparation method comprises the following steps:

[0039] (1) Decoction: Grind Rehmannia glutinosa, Astragalus membranaceus, Chinese yam, curculigo, Epimedium, Atractylodes macrocephala, cuttlebone octopus, Salvia miltiorrhiza and Angelica into particles with a particle size of 500-1000 microns, and then decoct. After the liquid is filtered respectively, the filtrate is obtained, and all the filtrates are mixed to form a premix for subsequent use;

[0040] (2) Drying: After the premix is ​​concentrated, then dried to make a mixed dry powder for subsequent use;

[0041] (3) Preparation of calcined oyster powder: add water to the calcined oyster, grind it into calcined oy...

Embodiment 2

[0044] A bone-reducing medicine for reducing phosphorus, made from the following raw materials:

[0045] Rehmannia glutinosa 7kg, astragalus 3kg, yam 12kg, curculigo 15kg, epimedium 25kg, Atractylodes macrocephala 3kg, sea octopus 8kg, salvia miltiorrhiza 12kg, angelica 4kg, calcined oyster 25kg.

[0046] Its preparation method comprises the following steps:

[0047](1) Decoction: Pulverize Rehmannia glutinosa, Astragalus, Chinese yam, Curcuma, Epimedium, Atractylodes, octopus, Salvia and Angelica into particles with a particle size of 500-1000 microns, and then add 5 times their weight. water, then boil the water for 30 minutes respectively, adopt the 200-mesh sieve to filter the decoction liquid to obtain a filtrate, and mix all the filtrates to form a premix for subsequent use;

[0048] (2) drying: the premix is ​​concentrated to 1 / 3 of the weight of the premix after being concentrated for 40 minutes, and then spray-dried to make the mixed dry powder for subsequent use;

...

Embodiment 3

[0052] A phosphate-lowering and bone-reinforcing medicine is prepared from the following raw materials:

[0053] Rehmannia glutinosa 5kg, Astragalus 5kg, Chinese yam 10kg, Curcuma 20kg, Epimedium 20kg, Atractylodes Rhizoma 5kg, Sea octopus 10kg, Salvia 10kg, Angelica 5kg, Calcined oyster 30kg.

[0054] Its preparation method comprises the following steps:

[0055] (1) Decoction: Smash Rehmannia glutinosa, Astragalus, Chinese yam, Curcuma, Epimedium, Atractylodes, octopus, Salvia and Angelica respectively, then add 10 times the weight of water, and then boil the water respectively. Cook for 50 minutes, use 300 mesh sieves to filter the decoction liquid to obtain a filtrate, and mix all the filtrates to form a premix for subsequent use;

[0056] (2) drying: after the premix is ​​concentrated at 65°C for 60 minutes, concentrated to 1 / 3 of the weight of the premix, and then spray-dried to make a mixed dry powder for subsequent use;

[0057] (3) the preparation of calcined oyster...

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Abstract

The invention relates to phosphorous reducing osteoprastics and a preparing method thereof. The phosphorous reducing osteoprastics is prepared from prepared rehmannia root, radix astragali, Chinese yam, rhizoma curculiginis, herba epimedii, calcined oyster shell and the like through the process of decocting, drying, mixing and the like. The phosphorous reducing osteoprastics has the advantages of obviously reducing plasma phosphate, supplementing plasma calcium, reducing parathyroid hormone in plasma and having good preventing and treating effect on renal osteopathy caused by chronic renal failure and being good in curative effect, small in side effect, convenient to take, low in price and capable of being accepted by the majority of patients.

Description

technical field [0001] The invention belongs to the field of food processing, and in particular relates to a phosphorus-reducing and bone-tonifying medicine and a preparation method thereof. Background technique [0002] Existing phosphorus binders such as calcium carbonate contain 40% calcium, and calcium acetate contains 25% calcium. These two phosphorus binders increase blood calcium while reducing phosphorus, and increase the calcium-phosphorus product, which is not conducive to secondary thyroid disease. Control of hyperparathyroidism; lanthanum carbonate, mostly imported or a Sino-foreign joint venture, is expensive and cannot be used by the public; cinacalcet is expensive and has many side effects. After entering renal failure, the following pathological changes appear: ①Reduced phosphorus excretion by the kidneys, leading to hyperphosphatemia, high phosphorus inhibits the activity and synthesis of hydroxylase, promotes calcium deposition in bone, reduces intestinal a...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P39/02A61P3/02A61P5/20A61P13/12A61P19/08A23L33/00A61K35/618
CPCA61K36/8945A23V2002/00A61K35/618A61K36/232A61K36/284A61K36/296A61K36/481A61K36/537A61K36/804A61K36/88A61K2236/331A61K2236/51A61K2300/00A23V2200/306A23V2250/21
Inventor 张春花汲广成郁丽丹胡亮于欣
Owner 张春花
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