A kind of oral ulcer patch and preparation method thereof
A technology for oral ulcers and filming, which is applied in the field of medicine, can solve the problems of drug dependence, side effects, and restrict the promotion and application of drugs, and achieve the effects of promoting contraction, prolonging shelf life, and accelerating swelling and healing.
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Embodiment 1
[0034] Embodiment 1, a kind of oral ulcer patch
[0035] The oral ulcer patch consists of the following components and parts by weight thereof:
[0036] 5 parts of oleanolic acid, 8 parts of sodium alginate, vitamin B 6 2 parts, 3 parts of chitosan, 40 parts of film-forming agent, 10 parts of lauryl glucoside, 16 parts of tributyl citrate and 400 parts of distilled water; The composition of element and citric acid is 4:4:1.2 by weight.
[0037] Preparation:
[0038]S1 Take half of the amount of distilled water and heat it to 75°C, add half of the amount of film-forming agent and stir until it is completely dissolved, filter while it is hot, take the filtrate, add tributyl citrate to the filtrate, and stir evenly to obtain a glue solution;
[0039] S2 Cool the mucilage solution obtained in step S1 to 35°C and add oleanolic acid, sodium alginate diester, vitamin B 6 , stir evenly, then add chitosan and glucoside, mix evenly, remove air bubbles, spread the film, and dry at 62...
Embodiment 2
[0042] Embodiment 2, a kind of oral ulcer patch
[0043] The oral ulcer patch consists of the following components and parts by weight thereof:
[0044] 8 parts of oleanolic acid, 14 parts of sodium alginate diester, vitamin B 6 3 parts, 6 parts of chitosan, 56 parts of film-forming agent, 15 parts of lauryl glucoside, 24 parts of tributyl citrate and 480 parts of distilled water; The composition of element and citric acid is 5:3:0.8 by weight.
[0045] Preparation:
[0046] S1 Take half of the amount of distilled water and heat it to 80°C, add half of the amount of film-forming agent and stir until it is completely dissolved, filter while it is hot, take the filtrate, add tributyl citrate to the filtrate, and stir evenly to obtain a glue solution;
[0047] S2 Cool the mucilage solution obtained in step S1 to 40°C and add oleanolic acid, sodium alginate diester, and vitamin B 6 , stir evenly, then add chitosan and glucoside, mix evenly, remove air bubbles, lay a film, and ...
Embodiment 3
[0050] Embodiment 3, a kind of oral ulcer patch
[0051] The oral ulcer patch consists of the following components and parts by weight thereof:
[0052] 10 parts of oleanolic acid, 18 parts of sodium alginate diester, vitamin B 6 4 parts, 8 parts of chitosan, 60 parts of film-forming agent, 18 parts of lauryl glucoside, 30 parts of tributyl citrate and 500 parts of distilled water; Described film-forming agent is made of sodium alginate, hydroxypropyl cellulose Vegetarian and citric acid are composed of 6:2:0.5 by weight.
[0053] Preparation:
[0054] S1 Take half of the amount of distilled water and heat it to 85°C, add half of the amount of film-forming agent and stir until it is completely dissolved, filter while it is hot, take the filtrate, add tributyl citrate to the filtrate, and stir evenly to obtain a glue solution;
[0055] S2 Cool the mucilage solution obtained in step S1 to 45°C and add oleanolic acid, sodium alginate diester, and vitamin B 6 , stir evenly, th...
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