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Endogenous gas nose expiration sampling and analyzing device

An analysis device and endogenous technology, applied in the field of endogenous gas signal molecular nasal exhalation sampling and analysis devices, can solve the problem of no control of upper respiratory tract gas test results, achieve stable and effective measurement results, and constant sampling flow rate Effect

Active Publication Date: 2016-12-07
SUNVOU MEDICAL ELECTRONICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method does not have any control over whether the environment and lower airway gases enter and affect the upper airway gas test results

Method used

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  • Endogenous gas nose expiration sampling and analyzing device
  • Endogenous gas nose expiration sampling and analyzing device
  • Endogenous gas nose expiration sampling and analyzing device

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0022] This embodiment uses figure 1 The device shown collects and analyzes nasal breath samples according to preset sampling flow and emptying requirements.

[0023] The following details the entire collection and analysis process:

[0024] 1) Sampling preparation stage: The subjects are required to not eat, smoke or exercise one hour before the test; before the test, the medical staff will input the sampling flow rate used in this test and the subject’s age, gender, height, and For parameters such as weight, the algorithm in the software will automatically calculate the volume that the subject needs to be emptied during sampling, and calculate the required emptying time and sampling time based on the sampling flow and sampling volume; The air outlet port (202) is connected to the nasal exhalation head made of silicone material. The nasal exhalation head is in the shape of an olive. The head and mouthpiece are dedicated consumables to avoid cross-infection.

[0025] 2) The nasal s...

specific Embodiment 2

[0029] This embodiment uses figure 2 The device shown collects and analyzes nasal breath samples according to preset sampling flow and emptying requirements.

[0030] After setting the sampling flow rate, first turn on the variable flow sampling module (400), three-way valve one (204) and three-way valve two (205) to collect the ambient gas after the environmental filter (207) into the air chamber (206) ; After the acquisition is completed, the subject is prompted to start exhaling, and the pressure sensor (102) monitors the exhalation pressure in real time; 5cmH 2 Start the variable flow sampling module (400) to pump air at 0, the ambient air enters the nasal cavity through the environmental filter (207), the three-way valve one (204) and the nasal air inlet (201), and then exits from the nasal air outlet (202) After passing through the three-way valve two (205) and variable flow sampling module (400), after the physiological dead space gas is discharged as required, open the th...

specific Embodiment 3

[0032] This embodiment uses image 3 The shown device collects samples of nasal breath and filtered ambient air according to preset sampling flow and emptying requirements, and sends them to an electrochemical analyzer for analysis.

[0033] The subject breathes out through the oral expiratory interface (101), and the pressure sensor (102) connected to the airway will monitor the expiratory pressure in real time; when the oral expiratory pressure meets> 5cmH 2 Start the variable flow sampling module (400) to pump air at 0, the ambient air enters the nasal cavity through the environmental filter (207), the three-way valve one (204) and the nasal air inlet (201), and then exits from the nasal air outlet (202) After passing through three-way valve two (205) and variable flow sampling module (400), after the physiological dead space gas is discharged as required, open three-way valve three (208), so that the sample that meets the requirements flows into the sampling air bag (500), Th...

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Abstract

The invention relates to an endogenous gas nose expiration sampling and analyzing device. The endogenous gas nose expiration sampling and analyzing device is composed of an expiration pressure monitoring module (100), a nose sampling module (200) and an analysis module (300), wherein the expiration pressure monitoring module (100) is composed of a mouth expiration connector (101) and a resistance part (103) which are connected in series, and a gas circuit is connected with a pressure sensor (102); the nose sampling module (200) is composed of a nose inspiration connector (201), a nose expiration connector (202), a bacterial filter (203), a three-way valve I (204), a three-way valve II (205), an air chamber (206), an environment filter (207) and a variable flow sampling module (400); the three-way valve I (204) and the three-way valve II (205) are used for switching collected nose sample gas or filtered environmental gas; and the analysis module (300) is composed of an analysis pump (301), a gas humidity regulator (302) and a NO sensor (303) which are connected in series.

Description

Technical field [0001] The invention relates to an endogenous gas signal molecule nasal breath sampling and analysis device. Background technique [0002] The endogenous gas signal molecules include NO, CO and H2S. They are secreted by cells in the body, significantly increase inflammation or cancer and other diseases, and are discharged from the body as breath. Therefore, by collecting and analyzing the concentration of these gases in the breath, the occurrence and development of diseases such as inflammation or cancer can be detected. The American Thoracic Society (ATS) and the European Respiratory Society (ERS) formulated international technical standards for the sampling and analysis of endogenous NO oral or nasal breath in 2005. It is recommended that (1) NO must be inhaled before testing. Gas <5ppb, to avoid the influence of high-concentration environmental NO on the test results; (2) During the test, the oral expiratory pressure must exceed 5cmH2O, and the soft palate ...

Claims

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Application Information

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IPC IPC(8): G01N1/22G01N33/48
CPCG01N1/2247G01N33/48
Inventor 韩益苹金俊奇韩杰
Owner SUNVOU MEDICAL ELECTRONICS
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