Application and preparation method of ceramic membrane with chiral Salen catalysis function

A technology of functional ceramics and ceramic membranes, applied in catalytic reactions, chemical instruments and methods, organic compound/hydride/coordination complex catalysts, etc., can solve the problem of low immobilization rate, insufficient reaction, conversion rate and ee value low level problem

Inactive Publication Date: 2016-12-21
BEIJING INSTITUTE OF TECHNOLOGYGY
View PDF9 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a preparation method and application of a ceramic membrane with chiral Salen catalytic function in order to solve the problems of insufficient reaction and low conversion rate and ee value caused by low immobilization rate in the prior art

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application and preparation method of ceramic membrane with chiral Salen catalysis function
  • Application and preparation method of ceramic membrane with chiral Salen catalysis function
  • Application and preparation method of ceramic membrane with chiral Salen catalysis function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A kind of preparation method with chiral Salen catalytic function ceramic membrane, such as figure 2 As shown, the specific steps are as follows:

[0037] Step 1, mono-CH 2 Synthesis of Cl-Salen-Mn(Ⅲ) catalyst:

[0038] 3-tert-butyl salicylaldehyde (product 1) is synthesized from 2-tert-butylphenol, and 3-tert-butyl salicylaldehyde is chloromethylated to synthesize 3-tert-butyl-5-chloromethyl salicylaldehyde ( Product 2); Synthesis of 3,5-di-tert-butyl salicylaldehyde (product 3) from 2,4-di-tert-butylphenol via Duff reaction, product 3 and (1R,2R)-(-)-cyclohexanedi Amine reaction to obtain (R,R)-N-3,5-di-tert-butyl salicylaldehyde-1,2-cyclohexanediamine (product 4); reaction of product 4 with product 2 to obtain (R,R)- N-(3,5-di-tert-butylsalicylaldehyde)-N-(3'-tert-butyl-5'-chloromethylsalicylaldehyde)-1,2-cyclohexanediamine (product 5), Product 5 and Mn(OAc) 2 .4H 2 O reflux reaction makes (R, R)-N-(3,5-di-tert-butyl salicylaldehyde)-N-(3'-tert-butyl-5'-chloro...

Embodiment 2

[0051] A method for preparing a ceramic membrane with chiral Salen catalytic function, the specific steps are as follows:

[0052] Step 1, mono-CH 2 Synthesis of Cl-Salen-Co(Ⅲ) catalyst:

[0053] 3-tert-butyl salicylaldehyde (product 1) is synthesized from 2-tert-butylphenol, and 3-tert-butyl salicylaldehyde is chloromethylated to synthesize 3-tert-butyl-5-chloromethyl salicylaldehyde ( Product 2); Synthesis of 3,5-di-tert-butyl salicylaldehyde (product 3) from 2,4-di-tert-butylphenol via Duff reaction, product 3 and (1R,2R)-(-)-cyclohexanedi Amine reaction to obtain (R,R)-N-3,5-di-tert-butyl salicylaldehyde-1,2-cyclohexanediamine (product 4); reaction of product 4 with product 2 to obtain (R,R)- N-(3,5-di-tert-butylsalicylaldehyde)-N-(3'-tert-butyl-5'-chloromethylsalicylaldehyde)-1,2-cyclohexanediamine (product 5), Product 5 and Co(OAc) 2 .4H 2 O reflux reaction makes (R, R)-N-(3,5-di-tert-butyl salicylaldehyde)-N-(3'-tert-butyl-5'-chloromethyl salicylaldehyde)-1, 2-cyc...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention belongs to the field of chiral catalysis and the technical field of membranes and relates to application and a preparation method of a ceramic membrane with a chiral Salen catalysis function. Grafted modified nano SiO2 particles with a Salen catalyst supported are filled into the ceramic membrane to obtain the ceramic membrane with the chiral Salen catalysis function. A reactor comprises an infusion pump, a feed liquid tank, a flow control valve, a liquid inlet, a liquid outlet, a sample taking port, an air inlet, an exhaust port, a stainless steel reaction vessel, a rubber seal ring and the like. According to the method, the grafted Salen catalyst supporting nano particles are filled into the ceramic membrane to construct a ceramic membrane reactor, immobilization rate of the Salen catalyst is increased, conversion rate and ee value of a chiral catalysis reaction are increased, a catalyst recycling process is simplified, and possibility is provided for continuous production.

Description

technical field [0001] The invention relates to a preparation method and application of a ceramic membrane with chiral Salen catalytic function, belonging to the field of chiral catalysis and the field of membrane technology. Background technique [0002] Asymmetric catalytic reactions can provide important intermediates for the synthesis of many natural products, optical materials, and optically active drugs, such as optically active epoxides, chiral alcohols or chiral aminoalcohols. Chiral Salen catalysts are excellent catalysts for asymmetric catalytic reactions. For example, in reactions such as kinetic resolution of aromatic alcohols, asymmetric catalytic epoxidation, aziridine, and hydrolytic kinetic resolution of epoxy compounds, Salen- Chiral Salen catalysts such as Mn, Salen-Co, and Salen-Cr all exhibit good asymmetry-inducing effects. The research and development of Salen catalysts have broad application prospects in the field of scientific research and industrial...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): B01J31/22B01J35/00B01J19/24
CPCB01J31/2217B01J19/2475B01J35/065B01J2231/72B01J2531/0252B01J2531/72B01J2540/40
Inventor 赵之平刘敏汪明鲁鹏
Owner BEIJING INSTITUTE OF TECHNOLOGYGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap