Rhizoma alismatis granules with efficacies of removing and preventing urinary calculus used for preventing and treating urinary calculus as well as preparation method and quality detection method

Abstract

The invention provides rhizoma alismatis granules with the efficacies of removing and preventing urinary calculus used for preventing and treating urinary calculus. A preparation method of the rhizoma alismatis granules comprises the following steps: taking the five medicinal materials, including rhizoma alismatis, herba plantaginis, herba desmodii styracifolii, poria cocos and cassia twig as the raw materials, adding with 8-fold amount of water, decocting the medicinal materials for twice, wherein each time is 2h, mixing the decoctions, filtering the obtained mixed decoction, concentrating the filtrate to obtain extract, adding with 1.5-fold amount of dextrin and 0.004-fold amount of steviosin, carrying out uniform mixing by adopting 80% alcohol as a wetting agent (the use amount of alcohol is 10% of that of the extract), and preparing the granules by adopting a conventional method. A quality detection method is characterized in that a thin-layer chromatography of herba desmodii styracifolii and cassia twig in the medicinal materials is adopted as an identification method, specifically, the contents of two active ingredients, namely, plantamajoside and schaftoside in the medicinal materials are measured by adopting a high performance liquid chromatography. The product is used for preventing and treating urinary calculus, and an extraction process is simple, stable and feasible; a quality standard detection method of the rhizoma alismatis granules with the efficacies of removing and preventing urinary calculus is sensitive and reliable and is strong in specificity.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a medicine for treating calculi in the urinary system, a preparation method and a quality detection method thereof. Background technique [0002] Urinary system calculus is a common urinary system disease, also known as urolithiasis, including kidney, ureter, bladder and urethral stones, of which kidney and ureteral stones are the most common. There are many factors that affect stone formation, mainly gender, age, race, genetics, dietary habits, environmental factors, and occupation, etc. [1] . The incidence of urinary calculi in human life is about 10%-15%, and some Middle Eastern countries even reach 20%-25%, and the prevalence rate is increasing year by year [2] . Urolithiasis is also very common in our country, which occurs in young adults, and the incidence rate has gradually increased in recent years. According to literature reports, the incidence rate of urinary calculi in my cou...

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Currently, extracorporeal shock wave lithotripsy (ESWL) and endourology can cure most patients wi

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