A Microparticle Separator Based on Negative Magnetophoresis Technology
A technology of microparticles and sorters, which is applied in the field of microfluidic systems, can solve the problems of poor sorting efficiency and difficulty in adapting the sorter to high-precision sorting of 1-20 micron particles, so as to ensure the sorting accuracy and avoid The integration of heater and control system ensures the effect of sorting efficiency
Inactive Publication Date: 2019-05-21
HANGZHOU DIANZI UNIV
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Problems solved by technology
[0006] Since the commonly used sorters are difficult to adapt to the high-precision sorting of 1-20 micron particles, and there are also shortcomings such as poor sorting efficiency, in order to strengthen the cross-streamline effect of fine particles, it is very meaningful to study particle sorting based on negative magnetophoresis technology
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Embodiment 1
[0028] Example 1, assuming that the magnetic fluid containing 3, 7, and 15 micron particles is introduced at the inlet 2, and the particle density is 1055 kg / m 3 , the entrance speed is 1-5mm / s, sorting after entering the sorting channel with a height of 600 microns, three permanent magnets (maximum magnetic strength 0.57T), can produce 488, 155, 25 microns in the straight channel part The lateral migration distance is derived at exit 10, exit 2 11 and exit 4 13 respectively.
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The invention belongs to the technical field of microfluidic systems and in particular relates to a particle separator based on a negative magnetophoresis technology. The particle separator based on the negative magnetophoresis technology is formed by bonding a substrate I and a substrate II, wherein an inlet used for importing liquid containing different particles and an outlet used for exporting the separated particles are formed in the substrate I; a separating channel connected with the inlet and the outlet of the substrate I is formed in the substrate II; the separating channel comprises a front wall surface and a rear wall surface; and a permanent magnet capable of driving the particles to make transverse negative magnetophoresis movement is embedded in the rear wall surface. The invention aims at providing a particle separator capable of performing particle separation according to the size by utilizing the negative magnetophoresis technology with the advantages of high separation efficiency and high precision.
Description
technical field [0001] The invention belongs to the technical field of microfluidic systems, in particular to a microparticle sorter based on negative magnetophoresis technology. technical background [0002] The microfluidic system is the main research direction of the lab-on-a-chip. It is a system that integrates sampling, dilution, mixing, reaction, detection, and separation. It can miniaturize complex biochemical analysis processes. It can reduce the consumption of sample liquid and detection liquid, and can also reduce energy consumption, and it can also improve the analysis speed and analysis accuracy. Therefore, microfluidic system technology has been widely used in environmental engineering, material engineering, medical testing and other fields. [0003] Particle sorting, such as biological cell sorting, particle separation in air, particle aggregation and sedimentation in water, etc., plays a very important role in materials engineering, medical engineering, and e...
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IPC IPC(8): B01L3/00
CPCB01L3/502761B01L2200/10B01L2300/0861B01L2300/0887
Inventor 王瑞金钱胜刘湘琪朱泽飞
Owner HANGZHOU DIANZI UNIV
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