A method to rapidly improve the resolution of ophthalmic optical coherence tomography imaging equipment
An optical coherence tomography, scanning imaging equipment technology, used in eye testing equipment, medical science, diagnosis, etc., can solve problems such as early diagnosis and treatment of unfavorable diseases, difficult observation, and difficulty in high-resolution imaging, to avoid images Blur or offset and the effect of low image resolution, increasing hardware cost
Inactive Publication Date: 2017-10-20
苏州轩睿医疗科技有限公司
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[0002] In recent years, optical coherence tomography imaging equipment has been widely used in ophthalmology, and in many cases, optical coherence tomography imaging equipment can provide ophthalmologists with images of layered structures, and can see the layers of each layer inside the eye (such as the retina). situation, but it is difficult to quickly see the details of a certain part of each layer (such as the optic nerve)
[0003] This is because the distance from the human eye lens (pupil) to the fundus is relatively long (about 2cm, slightly different for different people), and the size of the human eye lens is about 2-2.4mm. Therefore, when the optical coherence tomography imaging equipment is used to examine the human eye, the structural details (micron level) of the fundus imaging are difficult to observe, which is not conducive to the early diagnosis and treatment of diseases
The existing method of optical coherence tomography imaging equipment to improve the resolution is through phase adjustment. This method requires a phase adjustment for each scan during ophthalmic examination. The speed is relatively slow, and it is difficult to achieve fast high-resolution imaging.
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[0021] Below in conjunction with embodiment the present invention will be further described.
[0022] The specific implementation process is as follows figure 1 shown, including the following steps:
[0023] Step 1: Input a low-resolution image polluted by distortion, blur, jitter, electrical and additive noise;
[0024] Second step: judge the quantity of input image, and total image frame number is expressed with N;
[0025] Step 3: Divide N frames of low-resolution images Yi(x, y) into several grids of the same size and size, and the image information contained in each grid is described mathematically by a matrix; use the K-SVD model Perform image mutual information fusion to obtain a non-deconvolution high-resolution image Z(x,y).
[0026] Step 4: Use the gradient algorithm to establish a sub-pixel offset model, construct an offset function G, and obtain the image pixel value of each grid by solving the offset function G, to finally obtain a high-resolution image X(x,y)....
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The invention discloses a method of fast increasing definition of optical coherence tomography imaging device for ophthalmology application. The method applies the super resolution reconstruction of sub-pixel offset to the optical coherence tomography imaging device for ophthalmology application. The method comprises the following steps: using image mutual information fusion to the low resolution image Yi(x,y) to eliminate the noise through K-SVD model, then using gradient algorithm to construct sub-pixel offset model to acquire high resolution image X(x,y). The method can solve the problems of blurry image, deviation, low image resolution and slow imaging speed of high resolution images caused by the shaking of patients in the diagnosis process. The method has no hardware cost increase.
Description
technical field [0001] The invention relates to the field of optical medical equipment, in particular to a method for rapidly improving the resolution of ophthalmic optical coherence tomography imaging equipment. Background technique [0002] In recent years, optical coherence tomography imaging equipment has been widely used in ophthalmology, and in many cases, optical coherence tomography imaging equipment can provide ophthalmologists with images of layered structures, and can see the layers of each layer inside the eye (such as the retina). situation, but it is difficult to quickly see the details of a certain part of each layer (such as the optic nerve). [0003] This is because the distance from the human eye lens (pupil) to the fundus is relatively long (about 2cm, slightly different for different people), and the size of the human eye lens is about 2-2.4mm. Therefore, when the optical coherence tomography imaging equipment is used to examine the human eye, the struct...
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IPC IPC(8): A61B3/10
CPCA61B3/0016A61B3/102
Inventor 王兆宏王仁薰
Owner 苏州轩睿医疗科技有限公司