Western medicinal compound for treating idiopathic pulmonary fibrosis and applications of western medicinal compound

Abstract

The invention discloses a western medicinal compound for treating idiopathic pulmonary fibrosis and applications of the western medicinal compound. The western medicinal compound is prepared by mixing piperazine adipate and prenylamine, wherein the mass ratio of piperazine adipate to prenylamine is (8-12):1. When the western medicinal compound is used for treating idiopathic pulmonary fibrosis, the administration dosage for adults is 1.8-2.0 mg / kg / day. The western medicinal compound has good treatment effects for idiopathic pulmonary fibrosis at all stages including the acute stage, subacute stage, chronic stage and acute attack stage of chronic idiopathic pulmonary fibrosis, the clinical experiment proves that the total effective rate of the western medicinal compound for idiopathic pulmonary fibrosis is 90.0-97.5 %, the relapse seldom occurs after the idiopathic pulmonary fibrosis is completely treated, no toxic and side effects exist, and the western medicinal compound has the wide application value.

Description

technical field [0001] The invention relates to the technical field of western medicine, in particular to a western medicine compound for treating idiopathic pulmonary fibrosis and its use. Background technique [0002] Interstitial lung disease (ILD), also known as diffuse interstitial lung disease (diffuse parenchymal lung disease, DPLD), refers to a large group of lung diseases with different properties. Its histological feature is that the lesions are diffusely distributed in both lungs and mainly invade the surrounding lung tissues, such as alveoli, alveolar septa, small airways and small blood vessels, and pulmonary interstitial structures. In the acute stage, various cell infiltrations in the alveolar wall and protein exudation in the alveolar cavity are the main symptoms; in the subacute stage, granulomas are the main symptoms; in the chronic stage, diffuse interstitial fibrosis appears, and "honeycombing" occurs in severe cases. [0003] Idiopathic pulmonary fibros...

AI Technical Summary

Problems solved by technology

However, the above-mentioned drugs for the treatment of idiopathic pulmonary fibrosis have disadvantages such as poor therapeutic effect and relatively large toxic and side effects.

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