Use of a composition containing a long-chain polyol as a base for e-liquids
A technology of long-chain polyols and polyols, applied in medical preparations containing active ingredients, medical preparations with non-active ingredients, organic active ingredients, etc.
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Embodiment 1
[0070] Example 1 : Preparation and analysis of 1,3-butanediol-based and glycerol-based compositions
[0071] Precisely 10.00 kg of 1,3-butanediol (sold for example by the company Kyowa under the name 1,3-butanediol, cosmetic grade), 1.00 kg of vegetable glycerin (sold by the company Oleon under the number Glycérine 4810, USP and PE pharmacopoeia grade), 450.0g of apple fruit flavor (sold by Safisis under the code PT 128) and 114.50g of plant nicotine (sold by Alchem International under the code Nicotine Free Base, pharmaceutical grade nicotine >99%) in a Mix precisely in a mechanically stirred glass mixture. Stirring of the mixture (50 rpm) was maintained for 20 minutes. A 500 g sample was taken for analysis. The measurement of the kinematic viscosity is then carried out at 25° C. by means of a Houillon viscometer tube m 943 with a coefficient of 0.35051.
[0072] result :
[0073] The viscosity at 20°C is equal to 65.2mm 2 / s.
Embodiment 2
[0074] Example 2 Preparation and analysis of glycerol-free compositions
[0075] The same procedure as Example 1 was followed, but 1 kg of 1,3-butanediol (supplied by Kyowa) according to Example 1 was used instead of glycerin of vegetable origin. Viscosity measurement was then performed under the same conditions as in Example 1.
[0076] result :
[0077] The viscosity at 20°C is equal to 101.2mm 2 / s.
Embodiment 3
[0078] Example 3 (Comparison): Evaluation of the effectiveness of different e-liquids
[0079] According to the same step as in Example 1, but with the synthetic propylene glycol (No. Propylene glycol, USP grade) instead of 1,3-butanediol. Viscosity measurements were then carried out at 20°C.
[0080] result :
[0081] The viscosity at 20°C is equal to 59.2mm 2 / s.
[0082] In conclusion, it can be determined that e-liquids based on 1,3-butanediol and associated or not with glycerol (Examples 1 and 2) have comparable viscosities to conventional e-liquids (Example 3).
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