Maca extract product preparation method and purpose thereof

A technology of maca extract and water extract, applied in the field of preparation of maca extract, can solve the problems of poor effect, low retention rate of maca amide, etc., to enhance sexual behavior, improve the level of testosterone, and widely The effect of the application foreground

Inactive Publication Date: 2017-04-26
SUN YAT SEN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Aiming at the problems of low retention rate of fat-soluble active ingredients such as macamide in maca and poor effect in the above background, the present invention provides a preparation method and application of maca extract

Method used

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  • Maca extract product preparation method and purpose thereof
  • Maca extract product preparation method and purpose thereof
  • Maca extract product preparation method and purpose thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0011] Embodiment 1: the preparation method of a kind of maca supercritical extract of the present invention

[0012] A kind of preparation method of Maca extract, after Maca medical material is pulverized, carry out supercritical CO 2 Extraction, the supercritical extraction conditions are: the volume fraction is 95% ethanol as entrainer, the solid-liquid ratio of medicinal material and entrainer is 1:1-1:3 (g / ml), extraction temperature is 40-55°C, extraction pressure is 30 -45MPa, extraction time 1-3 hours, supercritical CO 2 The supercritical extract is obtained after extraction, the residue is extracted with water, the extraction temperature is 60-80°C, the number of extractions is 1-2 times, and the extraction time is 0.5-1.5 hours each time. Alcohol precipitation at high temperature for 6-12 hours, after concentration, spray drying under the conditions of inlet air temperature 190°C, outlet air temperature 120°C, and feed rate 300mL / h to obtain water extract, and combi...

Embodiment 2

[0013] Embodiment 2: the purposes of a kind of maca supercritical extract of the present invention

[0014] Select SPF grade Kunming mice, male, 9-11 weeks old, 40 mice, and randomly divide them into blank group, supercritical group, water extract group, and maca extract group, 10 mice in each group. Wherein, supercritical group is the supercritical extract in the embodiment 1 of 24mg / kg dosage every day, and water extract group is the water extract in the embodiment 1 of 24mg / kg every day dosage, Maca extract The Maca extract in Example 1 was administered to the group every day at a dosage of 24 mg / kg, and the blank group was replaced with an equal amount of distilled water. Oral administration once a day for 14 consecutive days. Another selection of SPF Kunming mice, female, aged 9 to 10 weeks, 80 mice, subcutaneously injected estradiol benzoate (0.02 mg / mouse) 48 hours before the observation of sexual behavior, and statistical indicators captured latency, mating latency, a...

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Abstract

The invention relates to a maca extract product preparation method and a purpose thereof. According to the method, a maca medical material is extracted by super CO2 to obtain a supercritical carbon dioxide extract, the residue is subjected to water extraction and alcohol precipitation as well as spray drying to obtain an aqueous extract, and the material and the aqueous extract are merged and uniformly stirred to obtain the maca extract having sexual function improving function. Compared with the prior art, the maca extract increases the level of testosterone, and concentration of factor cGMP and NO related with penile erection, enhances the sexual behavior of mice, and can be taken as a health product for improving sexual function.

Description

technical field [0001] In particular, the present invention relates to a preparation method and application of maca extract. Background technique [0002] Male sexual activity mainly includes five aspects: sexual desire, penile erection, sexual intercourse, ejaculation and orgasm. With the acceleration of the pace of life, various factors such as physical illness, family, and society lead to loss of libido and erectile dysfunction. Maca is an annual or biennial herbaceous plant belonging to the genus Brassicaceae. It has the reputation of "South American ginseng", and its main medicinal part is its root. Maca is not only rich in carbohydrates, protein, fat and potassium, calcium, magnesium, copper and other minerals, but also contains trace amounts of macamide, macaene, glucosinolate and benzyl isothiocyanate, etc. active ingredient. A large number of animal experiments have proved that Maca has the functions of enhancing sexual function, improving fertility, improving hu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/31A61P15/08
CPCA61K36/31A61K2236/53A61K2236/37A61K2236/39A61K2236/51A61K2236/331
Inventor 葛发欢周飞贤张易史庆龙马晋芳段明慧蒋华壮范彩虹
Owner SUN YAT SEN UNIV
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