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Light stream vortex array based material distributed control platform and control method

A distributed control and control method technology, applied in chemical instruments and methods, laboratory containers, laboratory stools/lab benches, etc., can solve problems such as limited range of action, distributed capture of difficult materials, etc., to achieve application Wide range of occasions, low cost, and simple system architecture

Active Publication Date: 2017-05-10
SOUTH CHINA NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, using one laser beam for excitation can only control the material located in the laser spot, and the range of action is limited. If you want to capture materials in multiple areas at the same time, you need to use multiple laser beams, which also means more experimental equipment and operations. To be done
Therefore, the current laser optical tweezers technology is difficult to realize the distributed capture of materials.

Method used

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  • Light stream vortex array based material distributed control platform and control method
  • Light stream vortex array based material distributed control platform and control method
  • Light stream vortex array based material distributed control platform and control method

Examples

Experimental program
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Effect test

Embodiment 1

[0057] This embodiment shows a distributed optical flow capture technology based on an optical flow vortex array. Such as image 3 As shown in a, the micro-nano materials near the vortex will be affected by two forces. The first force is a viscous force and its direction is along the vortex flow direction. The second force is a lift force whose direction is perpendicular to the vortex flow direction and points to the vortex center. Under the action of viscous force and lift force, the micro-nano materials will enter the center of the vortex in a spiral trajectory. Therefore, the center of the vortex can be used as a stable point for capturing material. Magrini convection can provide four vortex centers, which means that four capture positions can be provided, thus realizing the distributed capture technology based on the optical flow vortex array. image 3 Shown in b-d is the overall process of vortex 1 and vortex 3 respectively capturing two polystyrene microspheres. At t=0s...

Embodiment 2

[0059] This embodiment shows an optical flow manipulation technique by tuning the power of a light source. Such as Figure 4 As shown in a, as the light input power increases, the photothermal heat source on the surface of the microfluid absorbs more light energy, releases more heat energy, and the temperature also increases. In this process, the microfluid spreads the thermal energy farther, so that the resulting Marangoni convection has a larger range and faster speed. The increase of the convection range affects the movement of the center of the vortex, and finally guides the capture material away from the light and heat source. Conversely, the reduction in power can also guide the capture material closer to the photothermal heat source. Figure 4 Shown in b-d is the experimental process of realizing optical flow control by tuning the light source power. Under the input power of 10mW, two polystyrene microspheres were captured by the vortex 2 and the vortex 4 and stopped at...

Embodiment 3

[0061] This embodiment shows the optical flow control technology by tuning the position of the photothermal heat source. Such as Figure 5 As shown in (a), under the control of the micro adjustment frame, the photothermal heat source moves from the old position to the new position on the surface of the microfluid. The disappearance of the photothermal heat source in the old position leads to the disappearance of Marangoni convection, while the new position The emergence of light and heat sources led to the emergence of Marangoni convection. In this process, the center of the vortex also moves from the old position to the new position, and finally guides the capture material to move from the old position to the new position. Figure 5 (b)-(d) shows the experimental process of realizing optical flow control by tuning the position of the photothermal heat source. When t=0s, under the input power of 10mW, four polystyrene microspheres are captured by the vortex 1-4 and stopped at t...

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Abstract

The invention discloses a light stream vortex array based material distributed control platform and a control method. An optothermal heat source on the surface of a microfluid is excited to produce Marangoni convection, the Marangoni convection comprises four vortexes, each vortex rotates in a certain direction, and the speed at the center is the lowest. The center of each vortex provides a stable potential barrier used for capturing a material. Once the material is captured to the center of the vortex, the rotation flow direction of the vortex provides a torque to drive the material to rotate (clockwise or anticlockwise). The vortex array moves along with the movement of micro-nano waveguide in a chip, so that a target is controlled to move directionally in the microfluid. On the basis that particles are captured and rotated through the vortex, the various particles, biological cells and the like, which are originally scattered in the microfluid and are not mutually contacted, are captured in the same vortex through attraction, the rotation of the various materials in the vortex promotes the mutual actions of the materials, so that the materials are induced to achieve the functions of automated assembly, etc.

Description

Technical field [0001] The invention belongs to the field of material manipulation, and specifically relates to a multifunctional control platform and control that realizes distributed capture, targeted manipulation, self-rotation, and automatic assembly of micro-nano materials, biological cells and their molecules based on optical flow vortex arrays method. Background technique [0002] In the microfluidic system, the realization of the capture, movement, and arrangement of various materials in the fluid is the basic means of material synthesis and analysis. It has a wide range of applications in the field of microsystems and biomedicine. In the past, the operation technology mainly realized the contact operation through the probe of the atomic force microscope. For the biochemical environment, such direct contact easily caused mechanical damage and pollution to the sample. Therefore, the use of external equipment to stimulate various fields to achieve remote control operation...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L9/02B01L3/00
CPCB01L3/5027B01L3/502707B01L9/02B01L2200/10
Inventor 邢晓波郑嘉鹏周瑞雪张俊优何赛灵杨剑鑫史可樟
Owner SOUTH CHINA NORMAL UNIVERSITY
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