Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of a kind of polypeptide in the preparation of medicine for treating enterovirus infection

A technology of enterovirus and medicine, which is applied in the field of preparation of polypeptides for the treatment of enterovirus infection, can solve problems such as the treatment of enterovirus infection that has not been seen, and achieve the promotion of ulcer healing, high safety and good effect Effect

Active Publication Date: 2020-08-14
ZHEJIANG ECHON BIOMEDICAL CO LTD
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The applicant discovered the polypeptide of the present invention in research, which is an antimicrobial peptide, and has applied for a number of patents on its antimicrobial and other properties before. The prior art only reports the antibacterial performance of the polypeptide, and no See its report on the treatment of enterovirus infection

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of a kind of polypeptide in the preparation of medicine for treating enterovirus infection
  • Application of a kind of polypeptide in the preparation of medicine for treating enterovirus infection
  • Application of a kind of polypeptide in the preparation of medicine for treating enterovirus infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1 Preparation of lyophilized formulation of the present invention

[0033] Dissolve the auxiliary materials mannitol and arginine, mix them with the polypeptide of the present invention, adjust the pH value to 7.2, and form a composition containing 1 mg of the polypeptide, 32 mg of mannitol, and 15 mg of arginine per milliliter of liquid. After filtering and sterilizing, freeze Drying is a freeze-dried preparation.

Embodiment 2

[0034] Embodiment 2 The preparation of spray according to the present invention

[0035] For the convenience of transportation and storage, the polypeptide of the present invention is prepared into a freeze-dried preparation, which can be prepared as a spray preparation according to the needs during use: the freeze-dried preparation is dissolved with physiological saline or a common medical solvent, and the concentration range of the polypeptide after dissolution is 0.01%, put it into a sprayer that meets the requirements, and it can be sprayed and used.

Embodiment 3

[0036] Embodiment 3 The preparation of lotion of the present invention

[0037] Stir 8% glycerin in purified water evenly, add 0.02% of the polypeptide, 0.5% arginine and 10% lysine to mix, stir evenly and adjust the pH to 7.2 to obtain the peptide lotion.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses application of polypeptide in preparing a medicine for treating enterovirus infection, belongs to the field of infectious disease prevention and treatment, further provides a medicinal composition for treating enterovirus infection, and in addition, provides a polypeptide preparation prepared from pharmaceutically acceptable auxiliary materials or auxiliary components. The medicinal composition comprises an effective dosage of the polypeptide as an active component. The polypeptide disclosed by the invention can be used for treating enterovirus infection, particularly for treating and preventing hand-foot-mouth diseases and herpetic herpangina, and is remarkable in effect and good in security.

Description

technical field [0001] The invention relates to the field of treatment of enterovirus infection, in particular to the use of a polypeptide in the preparation of medicines for treating enterovirus infection. Background technique [0002] Enteroviruses (Enteroviruses, EVs) are a class of pathogens that invade and multiply in intestinal cells, which can induce various inflammations in human intestinal epithelial cells. Enteroviruses belong to the genus Enterovirus of the family Picornaviridae, including poliovirus (PV), Echovirus (Echovirus), Coxsackievirus (CVA, CVB), and new enteroviruses, a total of 106 serum type. According to biological and genetic characteristics, it is divided into 4 groups (species) (Kenowles NJ, Hovi T, Hyypia T, et al. Classification and nomenclature of virus: ninth report of the international committee on taxonomy of viruses. San Diego: Elsevier, 2011): Enterovirus A (EV-A) includes 21 serotypes, Enterovirus B (EV-B) includes 60 serotypes, and Ente...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/10A61P1/00A61P31/12A61P31/14
CPCA61K38/10
Inventor 凌建群章殷捷
Owner ZHEJIANG ECHON BIOMEDICAL CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com