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Medicine composition for treating insomnia and preparation method thereof

The technology of a composition and medicine is applied in the field of pharmaceutical composition for treating insomnia and its preparation, and can solve the problems of large toxic and side effects and the like

Inactive Publication Date: 2017-05-31
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chemical medicines improve sleep quickly, but have severe side effects. Some traditional Chinese medicines are effective and non-dependent in improving sleep, which is the current and future development trend of sleep-improving medicines.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: the pharmaceutical composition for the treatment of insomnia and its preparation method

[0038] The composition and parts by weight of the raw material of the pharmaceutical composition for treating insomnia are: betulinic acid 10g, mulberry snails 264g, oyster vegetables 224g, burnet saponin II 15g, betrine 8g, and asiatic acid 4g;

[0039] Preparation:

[0040] (1) According to the ratio of raw materials, take betulinic acid, mulberry snails, oysters, burnet saponin II, benzine, and asiatic acid, mix them evenly, use ethanol with a concentration of 22% by weight as a solvent, and mix them at 35 ℃ warm immersion extraction, the number of extractions is 12 times, each extraction time is 6 hours, and the amount of solvent used each time is 28 times the total weight of the crude drug, and filtered to obtain medicinal residue A and extract A, and the extract A reclaims ethanol, Concentrate to a relative density of 1.11, filter, and the drug solution passes ...

Embodiment 2

[0043] Embodiment 2: the pharmaceutical composition for the treatment of insomnia and preparation method thereof

[0044] The composition and parts by weight of the raw material of the pharmaceutical composition for treating insomnia are: betulinic acid 5g, mulberry snails 268g, oyster vegetables 222g, burnet saponin II 16g, benzine 7g, asiatic acid 5g;

[0045] Preparation:

[0046] (1) According to the ratio of raw materials, take betulinic acid, mulberry snails, oysters, burnet saponin II, benzine, and asiatic acid, mix them evenly, use ethanol with a concentration of 22% by weight as a solvent, and mix them at 35 ℃ warm immersion extraction, the number of extractions is 12 times, each extraction time is 6 hours, and the amount of solvent used each time is 28 times the total weight of the crude drug, and filtered to obtain medicinal residue A and extract A, and the extract A reclaims ethanol, Concentrate to a relative density of 1.11, filter, and the drug solution passes t...

Embodiment 3

[0049] Embodiment 3: the pharmaceutical composition for the treatment of insomnia and its preparation method

[0050] The composition and parts by weight of the raw material of the pharmaceutical composition for treating insomnia are: betulinic acid 15g, mulberry snails 262g, oyster vegetables 226g, burnet saponin II 13g, benzine 9g, asiatic acid 3g;

[0051] Preparation:

[0052] (1) According to the ratio of raw materials, take betulinic acid, mulberry snails, oysters, burnet saponin II, benzine, and asiatic acid, mix them evenly, use ethanol with a concentration of 22% by weight as a solvent, and mix them at 35 ℃ warm immersion extraction, the number of extractions is 12 times, each extraction time is 6 hours, and the amount of solvent used each time is 28 times the total weight of the crude drug, and filtered to obtain medicinal residue A and extract A, and the extract A reclaims ethanol, Concentrate to a relative density of 1.11, filter, and the drug solution passes thro...

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PUM

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Abstract

The invention discloses a medicine composition for treating insomnia and a preparation method thereof. The medicine composition is prepared by taking betulinic acid, succinea erythrophana ancey, ulva conglobata kjellm, ziyuglycoside II, adlumidine and asiatic acid as crude drugs through matching. The medicine composition disclosed by the invention can be prepared into various preparation forms according to a conventional preparation technology, and the treatment effect in treating the insomnia is remarkable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a medicinal composition for treating insomnia and a preparation method thereof. Background technique [0002] Sleep is one of the most basic physiological behaviors and an important condition for ensuring physical and mental health. Sleep disorders are common diseases and accompanying symptoms of various diseases. Long-term insomnia will bring huge physical and mental damage to patients and seriously affect people's life and work. Insomnia is a class of illnesses characterized by lack of nourishment or restlessness due to internal injuries from emotions, diet, or after illness and old age, insufficient endowment, guilty conscience and timidity, resulting in the inability to obtain normal sleep. The main manifestations are insufficient sleep time and depth and inability to eliminate fatigue and restore physical strength and energy. In mild cases,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/02A61P25/20A61K35/618A61K31/704A61K31/56A61K31/4741
CPCA61K31/4741A61K31/56A61K31/7048A61K35/618A61K36/02A61K2236/331A61K2236/39A61K2236/55A61K2300/00
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD