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Externally-used traditional Chinese medicine preparation for treating eczema and psoriasis and preparation method thereof

An external preparation, a technology for psoriasis, applied in the field of traditional Chinese medicine, can solve the problems of immediate recurrence, canceration, and increased difficulty in treatment

Active Publication Date: 2017-05-31
张颖
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the main oral drugs include anti-tumor and immunosuppressive drugs, immunomodulators, adrenal glucocorticoid drugs, cytostatic agents, reducing agents, antibiotics, and keratin exfoliants. External drugs include coal tar, salicylic acid, Anthralin, corticosteroid hormones and vitamin D3 derivatives, etc., although the treatment with these drugs has a very significant effect on the disappearance of skin lesions in a short period of time, after long-term use, not only the patient will become dependent on the drugs, but once the drugs are stopped, the condition will worsen. It will relapse immediately, which will increase the difficulty of later treatment, and it is expensive, with high toxicity and side effects. Long-term use will cause skin aging or canceration. Long-term use will damage the liver function, kidney function, and hematopoietic system to varying degrees.
[0005] With the development of traditional Chinese medicine, traditional Chinese medicine occupies an important position in the modern treatment of eczema and psoriasis, has relatively rich treatment experience, has been recognized by more and more people, and won praise from many patients. There are also many traditional Chinese medicines for external use in the treatment of eczema and psoriasis, such as Pulian ointment, Jinghongfen ointment, Douqing ointment, Yuhuang ointment, Hongfen ointment, camptothecin ointment, Binghuangfule ointment, etc. Although these drugs are toxic The side effects are small, but these traditional Chinese medicines for external use often contain heavy metal drugs, which are greatly limited in safety. Among them, camptothecin ointment is developed according to the mechanism of anti-tumor cell proliferation in Western medicine, and the effect is good. It is mainly used for scalp psoriasis disease, but it is very irritating to the skin, so it cannot be used in the progressive period, nor can it be used on a large area; In the process of application, it is still found that there is strong irritation, and it cannot effectively eradicate eczema and psoriasis. Generally speaking, there is no ideal and exact traditional Chinese medicine treatment for eczema and psoriasis that does not need to be taken orally.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The Chinese medicine external preparation and preparation method thereof for the treatment of eczema, psoriasis described in present embodiment 1, its preparation method is as follows:

[0017] ①Material preparation: Weigh various raw materials according to the following parts by weight, 25 parts of Sophora flavescens, 25 parts of Kochia chinensis, 20 parts of white fresh skin, 20 parts of raw rhubarb, 20 parts of purslane, 10 parts of windproof, 1 part of nepeta, 5 parts of alum, 8 parts of Cnidium, 20 parts of Burnet, 5 parts of Gardenia, and 20 parts of Herba Cnidium; Rhubarb, white fresh skin, purslane, windproof, nepeta, cnidium, burnet, gardenia and scorpion grass are sliced ​​and mixed for later use. The powder particle size of raw rhubarb powder is all less than 24 mesh, and the powder of ≤50 mesh is not more than 40%, the purslane and Nepeta are dried stems and leaves, the white fresh bark is the dried root bark, the Kochia scoparia and Fructus Gardenia Cnidii ...

Embodiment 2

[0022] The Chinese medicine external preparation and preparation method thereof for the treatment of eczema, psoriasis described in present embodiment 2, its preparation method is as follows:

[0023] ① Raw material preparation: Weigh various raw materials according to the following parts by weight, 30 parts of Sophora flavescens, 30 parts of Kochia chinensis, 30 parts of white fresh skin, 30 parts of raw rhubarb, 30 parts of purslane, 20 parts of windproof, 20 parts of nepeta, 10 parts of alum, 10 parts of cnidium, 30 parts of burnet, 10 parts of gardenia and 30 parts of scorpion. Herba oleracea, white fresh skin, purslane, windproof, nepeta, cnidium, burnt elm, gardenia and pigtail grass are sliced ​​and mixed for later use. The purslane and nepeta are dried stems and leaves, and the white fresh The skin is the dried root bark, the Kochia scoparia and Fructus Gardenia Cnidii are dried mature fruits, the Burnet, Radix Radix and Sophora flavescens are dried roots, and the rhub...

Embodiment 3

[0028] The Chinese medicine external preparation for the treatment of eczema, psoriasis described in present embodiment 3 and preparation method thereof, its preparation method is as follows:

[0029] ①Material preparation: Weigh various raw materials according to the following parts by weight, 50 parts of Sophora flavescens, 50 parts of Kochia scoparia, 40 parts of white fresh skin, 40 parts of raw rhubarb, 20 parts of purslane, 30 parts of windproof, 10 parts of nepeta, 20 parts of alum, 15 parts of cnidium, 40 parts of burnet, 20 parts of gardenia and 40 parts of scorpion grass. Fructus Rhizoma Rhubarb, Fresh Peel, Purslane, Fangfeng, Schizonepeta, Cnidium Fructus, Burnet, Gardenia, and Scutellaria chinensis are sliced ​​and mixed for later use. The powder particle size of the raw rhubarb powder is all less than 24 mesh, and the powder of ≤50 mesh No more than 40%, the purslane and Nepeta are dried stems and leaves, the white fresh bark is the dried root bark, the Kochia sc...

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PUM

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Abstract

The invention discloses an externally-used traditional Chinese medicine preparation for treating eczema and psoriasis and a preparation method thereof. The externally-used traditional Chinese medicine preparation is prepared from the following raw materials: 25 to 50 parts of lightyellow sophora root, 25 to 50 parts of fructus kochiae, 20 to 40 parts of cortex dictamni, 20 to 40 parts of radix et rhizoma rhei, 20 to 40 parts of herba portulacae, 10 to 30 parts of radix saposhnikoviae, 10 to 30 parts of herba schizonepetae, 5 to 20 parts of alumen, 8 to 15 parts of fructus cnidii, 20 to 40 parts of radix sanguisorbae, 5 to 20 parts of fructus gardeniae and 20 to 40 parts of siegesbeckia orientalis. The preparation method comprises the following steps: putting and soaking smashed radix et rhizoma rhei into cold water, then adding the alumen and hot water, and carrying out percolation after dissolving the alumen into the hot water, thus obtaining percolate; then carrying out twice decocting on a mixture of other slices, and standing and filtering two filter solutions after decocting, thus obtaining a concentrated solution; finally, after uniformly mixing the prepared percolation with the concentrated solution, adding sodium benzoate, thus preparing the externally-used traditional Chinese medicine preparation for treating the eczema and the psoriasis. The externally-used traditional Chinese medicine preparation disclosed by the invention not only is high in recovery rate, low in recurrence rate and small in irritation, but also has no any toxic and side effects after long-term use.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicinal preparation for treating eczema and psoriasis and a preparation method thereof. Background technique [0002] Eczema is a common skin disease with complex etiology and severe itching clinically. In the acute phase, it is dominated by papules and has a tendency to exudate. In the chronic phase, it is dominated by lichenification, which is prone to repeated attacks. Eczema-like dermatitis is also a common and frequently-occurring disease in dermatology. It is an allergic skin disease caused by complex internal and external stimulating factors. It is not only dominated by genetic factors, but also affected by health status and environmental factors. , the surrounding skin is eroded, the patient has a long course of disease, severe itching, and strong relapse, and the surface of the patient's rash is often accompanied b...

Claims

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Application Information

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IPC IPC(8): A61K36/75A61P17/00A61P17/06A61K33/06
CPCA61K9/0014A61K33/06A61K36/185A61K36/234A61K36/238A61K36/28A61K36/489A61K36/538A61K36/708A61K36/739A61K36/744A61K36/75A61K47/12A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 张颖
Owner 张颖
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