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Drug composition capable of treating liver injury

A liver injury and composition technology, which is applied in the field of pharmaceutical compositions for the treatment of liver injury, can solve the problems of backward preparation process and dosage form, many ineffective ingredients and impurities, and large dosage, so as to improve curative effect, improve immunity, and take The effect of a small dose

Inactive Publication Date: 2017-06-13
呼伦贝尔欣验芳民间医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the existing traditional Chinese medicines have complex ingredients, inaccurate curative effects, large blessing effects, backward preparation technology and dosage forms, many ineffective ingredients and impurities, and large dosages. For patients with liver damage, taking a large amount of drugs will often aggravate the condition , and even have serious side effects

Method used

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  • Drug composition capable of treating liver injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A pharmaceutical composition for treating liver damage, the ingredients are as follows:

[0019] Huhuanglian 100g

[0020] blue pot flower 100g

[0021] Sophora japonica 100g

[0022] The preparation method is as follows: the above medicines are mixed, pulverized into fine powder, sterilized, packaged and made into powder.

[0023] Usage and dosage: Take after boiling water, 2 times a day, 15g each time.

Embodiment 2

[0025] A pharmaceutical composition for treating liver damage, the ingredients are as follows:

[0026] Huhuanglian 500g

[0027] blue pot flower 100g

[0028] Sophora japonica 100g

[0029] The preparation method is as follows: after mixing the above medicines, add water to decoct and extract for 3 times, each time for 1 hour, combine the extracts and concentrate them into extracts, granulate with powdered sugar to make granules.

[0030] Usage and dosage: Take it with boiling water, 2 times a day, 10g each time (equivalent to 12g of medicinal materials).

Embodiment 3

[0032] A pharmaceutical composition for treating liver damage, the ingredients are as follows:

[0033] Huhuanglian 300g

[0034] Blue Pot Flower 200g

[0035] Sophora japonica 100g

[0036] The preparation method is as follows: take Huhuanglian and Lanpenhua, extract twice with 60% ethanol under reflux, each time for 2 hours, combine the extracts and concentrate them into an extract; crush Sophora japonica into fine powder, mix the extract with the fine powder, Soft materials, granulated, made into granules.

[0037] Usage and dosage: Take it with boiling water, 2 times a day, 8g each time (equivalent to 10.5g of medicinal materials).

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Abstract

The invention discloses a drug composition capable of treating liver injury. The drug composition is prepared from the following raw materials in parts by weight: 1-5 parts of rhizoma picrorhizae, 1-5 part of flos scabiosa tschiliensis and 1-5 parts of flos sophorae immaturus. The invention also discloses a preparation method for traditional Chinese medicines. According to the drug composition, the contents of AST (Aspartate Transaminase) and ALT (Alanine AminoTransferase) in serum can be lowered, the contents of ALB (serum albumin) are improved, the contents of triglyceride in the serum are lowered, the contents of TP (Total Protein) in the serum are improved, and the contents of bilirubin and alkaline phosphatase in the serum are lowered. The drug composition is disclosed to own obvious functions of protecting liver, lowering transaminase and improving immunity, and can be used for preventing and treating hepatocyte damage and hepatic fibrosis caused by chronic hepatitis, viral hepatitis, alcoholic hepatitis, drugs and the like.

Description

technical field [0001] The invention belongs to the field of pharmacy, and in particular relates to a pharmaceutical composition for treating liver damage. Background technique [0002] The function of the liver in the human body is very important. Once damaged, it will affect the functions of metabolism, detoxification, immunity and antimicrobial. Hepatocytes in the normal adult liver are long-lived cells that rarely divide and proliferate. However, after liver damage, especially after partial hepatectomy, the remaining hepatocytes rapidly undergo active division and proliferation. Liver cell regeneration is a highly compensatory response to viral, chemical, ischemic and immune injuries and after partial hepatectomy. Animal experiments have shown that 70-80% of the normal liver can be resected, and normal physiology can still be maintained. Features. [0003] After liver injury, the active regeneration of liver cells is the key to the maintenance of liver function. There...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/80A61P1/16
CPCA61K36/185A61K36/489A61K36/80A61K2236/15A61K2236/333A61K2300/00
Inventor 黄晓华
Owner 呼伦贝尔欣验芳民间医药研究院
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