Preparation method of Lanqin oral liquid (oral liquid containing radix isatidis and radix scutellariae)

Abstract

The invention discloses a preparation method of Lanqin oral liquid (oral liquid containing radix isatidis and radix scutellariae). A major technological process comprises the following steps: 1, keeping a plurality of traditional Chinese medicines including Lanqin (a compound of radix isatidis and radix scutellariae), radix isatidis, fructus gardeniae and the like in a beaker, decocting the traditional Chinese medicines with the addition of a proper amount of water for 3-5 times, and filtering an obtained decoction; 2, combining filtrates obtained from 3-5 times of decocting, adding the combined filtrates to a designated container and concentrating the combined filtrates to a certain concentration; 3, preparing a chitosan clarifying agent: weighing chitosan, adding water and glacial acetic acid, uniformly stirring all materials, heating an obtained mixture to 70-90 DEG C, adding water to a certain volume and preserving heat for 40-60min for later use; 4, adding the prepared chitosan clarifying agent, conducting heating in a water bath at a constant temperature of 70-90 DEG C and simultaneously conducting stirring for 15-30min, taking out an obtained solution and keeping the solution at 0-5 DEG C; and 5, reserving supernatant liquid, blending the supernatant liquid with a proper amount of purified water to a certain volume, and conducting filling and sterilizing so as to obtain the finished product (the Lanqin oral liquid). The preparation method can protect active ingredients of traditional Chinese medicines from being damaged and can reserve the active ingredients to the greatest extent; the preparation method can effectively remove such unstable ingredients as phenol substances, protein, colloid and the like in Chinese herbal medicines; the preparation method is economic and practicable and is capable of saving a great amount of expenses; and the preparation method has a certain application prospect and is applicable to industrial production.

Description

technical field [0001] The invention relates to the technical field of oral liquid and its preparation method, in particular to a preparation method of Lanqin oral liquid. Background technique [0002] Lanqin oral liquid is mainly extracted from Radix Isatidis, Scutellaria baicalensis, Gardenia, etc. It has the effects of clearing away heat and purging fire, detoxifying and reducing swelling, relieving sore throat and relieving pain. [0003] The traditional method of preparing the oral liquid is the water extraction and alcohol precipitation method. The process is to weigh the various medicinal materials according to the prescription, add an appropriate amount of water to decoct 3 times, combine the decoction liquid, concentrate to a relative density of 1.10, add ethanol, and make the ethanol The volume is about 60%, stand at 0-5°C for more than 24 hours, take the supernatant, recover the ethanol under reduced pressure until it is exhausted, concentrate to a relative densit...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a preparation method of Lanqin Oral Liquid under the circumstances that a large amount of ethanol is required for the current preparation of Lanqin Oral Liquid, the process cycle is long, and the operation is cumbersome