Medicine for treating dental ulcer and stomatitis, as well as preparation method and application thereof

A technology for oral ulcers and stomatitis, applied in the field of medicine, can solve the problems of analgesia, astringency of wounds, anti-inflammatory and detumescence effects, long course of disease, etc. Good results

Inactive Publication Date: 2017-06-23
JIAMUSI UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned medicines have been through the clinical treatment of many patients, and the effects of pain relief, astringent wound surface, anti-inflammatory and detumescence are not satisfactory, especially there are shortcomings of repeated medication and long course of disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] In an embodiment of the present invention, a medicine for treating oral ulcer and stomatitis is composed of the following raw materials: 10 kg of bay leaf, 1 kg of cicada slough, 28 kg of hemp, 23 kg of eclipta, and 15 kg of peppermint. Weigh the fragrant leaves, cicada slough, jiji, eclipta, and mint respectively. Firstly, the leaves and fenugreek are crushed to 40 meshes, and after adding water to extract, the filtrate is combined and concentrated to a water content of 28% to obtain mixed material A; the method of adding water to extract is: adding water 7 times the mass of the two for the first time Decoct for 1.8h, add water 5 times the mass of the two for the second time and decoct for 1.2h, and add water 3 times the mass of the two for 0.8h for the third time. The cicada slough is superfinely pulverized and passed through a 700-mesh sieve to obtain the cicada slough powder for later use. Crush eclipta and mint, pass through a 200-mesh sieve, add to water 12 times...

Embodiment 2

[0031] In an embodiment of the present invention, a medicine for treating oral ulcer and stomatitis is composed of the following raw materials: 20 kg of bay leaf, 5 kg of cicada slough, 36 kg of hemp, 31 kg of eclipta, and 25 kg of peppermint. Weigh the fragrant leaves, cicada slough, jiji, eclipta, and mint respectively. Grind the leaves and fenugreek to 60 mesh first, add water to extract and then combine the filtrate and concentrate to a water content of 30% to obtain the mixed material A; the method of adding water to extract is: add water 7 times the mass of the two for the first time Decoct for 2 hours, add water 5 times the mass of the two for the second time and decoct for 1.5 hours, and add water 3 times the mass of the two for 0.8 hours for the third time. The cicada slough is superfinely pulverized and passed through a 700-mesh sieve to obtain the cicada slough powder for later use. Crush Eclipta and mint, pass through a 200-mesh sieve, add to water 12 times the ma...

Embodiment 3

[0033] In an embodiment of the present invention, a medicine for treating oral ulcer and stomatitis is composed of the following raw materials: 12kg of bay leaf, 2kg of cicada slough, 30kg of hemp, 25kg of eclipta, and 18kg of peppermint. Weigh the fragrant leaves, cicada slough, jiji, eclipta, and mint respectively. Firstly, the leaves and fenugreek are crushed to 60 mesh, and after adding water to extract, the filtrate is combined and concentrated to a water content of 29% to obtain mixed material A; the method of adding water to extract is: adding water 7 times the mass of the two for the first time Decoct for 1.9 hours, add water 5 times the mass of the two for the second time and decoct for 1.3 hours, and add water 3 times the mass of the two for 0.8 hours for the third time. The cicada slough is superfinely pulverized and passed through a 700-mesh sieve to obtain the cicada slough powder for later use. Crush Eclipta and mint, pass through a 200-mesh sieve, add to water ...

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PUM

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Abstract

The invention discloses a medicine for treating dental ulcer and stomatitis, as well as a preparation method and application thereof. The medicine is prepared from the following raw materials in parts by weight: 10 to 20 parts of myrcia, 1 to 5 parts of periostracum cicada, 28 to 36 parts of radix chloranthi serrati, 23 to 31 parts of herba ecliptae and 15 to 25 parts of mint. The preparation method comprises the following steps: smashing the myrcia and the radix chloranthi serrati, adding water for extraction, and carrying out concentration, thus obtaining a mixed material A; carrying out ultrafine smashing on the periostracum cicada, thus obtaining periostracum cicada powder; smashing the herba ecliptae and the mint, adding water for soaking, boiling and centrifugation, and taking supernate; carrying out reduced pressure distillation and concentration, thus obtaining a mixed material B; mixing the mixed material A, the periostracum cicada powder and the mixed material B, slowly adding ethyl alcohol for heating stirring, standing and centrifugation, and taking precipitates; adding water into the precipitates for dissolving, heating to remove the ethyl alcohol, and drying the precipitates, thus obtaining the medicine. The medicine disclosed by the invention is good in pain relieving effect when treating the dental ulcer and stomatitis and high in wound convergence speed, can quickly diminish inflammation and swelling, has short treatment time, does not have toxic or side effects, and further can be used for preventing and treating the dental ulcer, the stomatitis and the like formed damage to the mouth mucosa caused by chemotherapy.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a medicine for treating oral ulcer and stomatitis, a preparation method and application thereof. Background technique [0002] Oral ulcer, commonly known as "oral sore", is a common ulcerative injury disease that occurs in the oral mucosa. It is more common in the inner lip, tongue, tongue belly, buccal mucosa, vestibular groove, soft palate and other parts. The mucosa in these parts lacks stratum corneum. or poor keratosis. Tongue ulcers refer to oral ulcers that occur on the tongue and the abdomen of the tongue. When oral ulcers attack, the pain is severe, and the local burning pain is obvious. In severe cases, it will also affect eating and speaking, causing great inconvenience to daily life; Symptoms such as swollen lymph nodes. Stomatitis is one of the most common complications during chemotherapy for malignant tumor patients. It not only affects the patient's eating, bu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61P1/02A61K35/64
Inventor 赵玥薛钢李冬梅王佳琦戴辛鹏
Owner JIAMUSI UNIVERSITY
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