Application of fine-leaf schizonepeta herb extract in preparation of antidepressant drugs

An extract and anti-depressant technology, applied in the field of medicine, can solve the problems of undiscovered nepeta extract and other public reports, and achieve the effect of developing application value, rich raw materials, and simple preparation method

Inactive Publication Date: 2017-07-21
HENAN UNIV OF CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, so far, no public reports on the antidepressant effect of Nepeta extract have been found.

Method used

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  • Application of fine-leaf schizonepeta herb extract in preparation of antidepressant drugs
  • Application of fine-leaf schizonepeta herb extract in preparation of antidepressant drugs
  • Application of fine-leaf schizonepeta herb extract in preparation of antidepressant drugs

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Embodiment Construction

[0009] The specific embodiments of the present invention will be described in detail below in combination with specific circumstances.

[0010] In the specific implementation of the present invention, the application of the Nepeta extract in the preparation of antidepressant drugs, the Nepeta extract is a Nepeta water extract or a Nepeta alcohol extract, and the Nepeta water extract is the Nepeta must be crushed through a 40-mesh sieve to form Chinese medicine powder. Add 100g of Chinese medicine powder to every 1000ml of water, soak for 30 minutes, boil for 30 minutes under high fire, filter to obtain the first medicinal liquid, and add 5 times the weight of Chinese medicine powder to the residue. , boiled for 30min, filtered to obtain the second medicinal liquid, combined the two medicinal liquids, concentrated to a concentrated solution equivalent to 1 g / ml of crude drug, and heated to dryness to obtain a dry product;

[0011] The alcohol extract of Nepeta must be pulverize...

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Abstract

The invention aims to provide application of a fine-leaf schizonepeta herb extract in preparation of antidepressant drugs. The fine-leaf schizonepeta herb extract is a fine-leaf schizonepeta herb water extract or a fine-leaf schizonepeta herb alcohol extract, wherein the fine-leaf schizonepeta herb water extract is a dried substance obtained by smashing a fine-leaf schizonepeta herb into traditional Chinese medicine powder, adding water for soaking, boiling the powder twice, mixing two medicinal liquids and performing concentration and drying, and the fine-leaf schizonepeta herb alcohol extract is a dried substance obtained by smashing the fine-leaf schizonepeta herb into traditional Chinese medicine powder, adding ethyl alcohol for soaking, reflux extraction is performed twice, mixing two extracting liquids and performing concentration and drying. The raw materials are rich, a preparation method is simple, the prepared fine-leaf schizonepeta herb extract has an antidepressant effect and is effectively used for preparing the antidepressant drugs, application of the fine-leaf schizonepeta herb extract in drug preparation is achieved, the application value of the fine-leaf schizonepeta herb is increased, and the fine-leaf schizonepeta herb extract is the innovation in traditional Chinese medicine and has good economic and social benefits.

Description

technical field [0001] The invention relates to medicine, in particular to the application of a Nepeta japonicus extract in the preparation of antidepressant medicines. Background technique [0002] As the pace of modern life continues to accelerate, people are increasingly stressed, and the incidence of depression is increasing year by year. At present, depression has become a mental disease that seriously endangers the physical and mental health of human beings. According to the statistics of the World Health Organization, depression has become the fourth largest disease in the world, and it is estimated that by 2020, it may become the second largest disease after coronary heart disease. Depression is a chronic, recurring brain disorder characterized by depression, feelings of emptiness, helplessness, sadness, and inexplicable impatience; disinterest in things, changes in diet and weight, insomnia or lethargy, emotional agitation or unresponsiveness , fatigue, listlessne...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/538A61P25/24
Inventor 栗俞程李寒冰马素珍李伟石宁张骆琪张娜李小洁唐维维
Owner HENAN UNIV OF CHINESE MEDICINE
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