Preparation method of caulis spatholobi extract and application

A technology for extracts and Scutellaria chinensis is applied in the field of preparation of extracts, which can solve the problems of complex traditional Chinese medicine ingredients, side effects of human body that cannot be ignored, etc., and achieves the effects of less pollution, simple and easy extraction and preparation methods, and convenient and easy-to-obtain raw material sources.

Inactive Publication Date: 2017-08-11
GUANGXI INST OF CHINESE MEDICINE & PHARMA SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, "the drug is three-point poisonous". After a variety of Chinese medicinal materials are combined to make antidepressant drugs, although the disadvantages of western medicine are solved, the ingredients of traditional Chinese medicine are complex, and they need to be taken for a long time, and the side effects on the human body cannot be ignored.

Method used

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  • Preparation method of caulis spatholobi extract and application
  • Preparation method of caulis spatholobi extract and application
  • Preparation method of caulis spatholobi extract and application

Examples

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Effect test

Embodiment 1

[0018] Example 1 Preparation of Spatholobus Spatholobus Extract

[0019] Take 1000g of the coarse powder of Mildew Spathifolia medicinal material, add 50% ethanol and heat it for extraction 3 times, 8L each time, combine the extracts, concentrate under reduced pressure to a certain concentration; add ethanol with a volume fraction of 85%, place in 4 Precipitate at ℃ for 12 hours, filter the filtrate, concentrate under reduced pressure, and dry at low temperature to obtain the extract.

Embodiment 2

[0020] Example 2 Preparation of Spatholobus Spatholobus Extract

[0021] Take 1000g of the crude powder of Mildew Spathifolia, add ethanol with a volume fraction of 80% and heat and extract 3 times, 10 L each time, combine the extracts, concentrate under reduced pressure to a certain concentration, add ethanol with a volume fraction of 65%, and place in 4 ℃ for 12 hours, and the filtrate was collected by filtration, concentrated under reduced pressure, and dried to obtain the extract.

Embodiment 3

[0022] Example 3 Preparation of Spatholobus Spatholobus Extract

[0023] Take 1000g of the crude powder of Mildew Spathifolia, add ethanol with a volume fraction of 100%, heat and extract 3 times, 12L each time, combine the extracts, concentrate under reduced pressure to a certain concentration; add ethyl acetate, place at 4°C for precipitation for 12h, The filtrate was collected by filtration, concentrated under reduced pressure, and dried to obtain the extract.

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Abstract

The invention discloses a preparation method of caulis spatholobi extract and an application. The preparation method comprises the following detailed steps of: taking crude caulis-spatholobi powder, adding into a solvent, heating for extraction, and after vacuum concentration to certain concentration, adding an organic solvent for precipitation; and filtering, taking filtrate, performing vacuum concentration, drying and obtaining the caulis spatholobi extract. The preparation method and the application disclosed by the invention have the advantages that the medicine taking resource is rich, the extract preparation method is simple and easy, the material is convenient and easy to obtain, and the preparation method can be used for large-scale preparation of the caulis spatholobi extract; and the cost is low, the pollution is less, the benefit for large-scale production under the conditions of saving energy and reducing emission is achieved and the industrial prospect is very clear. The caulis spatholobi extract can be used for multiple purposes from foods and health-care products to preparation of medicines for special diseases so as to have scientific basis for clinic application in the aspect of preventing or treating depression.

Description

technical field [0001] The invention belongs to the technical field of natural extracts, and in particular relates to a preparation method and application of an extract of Spatholobus Spatholobus. Background technique [0002] Depression is an affective mental disorder, and its main clinical features are significant and persistent negative mood, loss of interest, unpleasant experience, sleep disturbance, and repeated suicidal thoughts. And often accompanied by cognitive, mental and motor impairment. It has the characteristics of high morbidity rate, high disability rate and high recurrence rate, and seriously endangers human health. According to statistics from the World Health Organization, the incidence of depression has been increasing year by year in recent years. About one-fifth of the people have different degrees of depressive symptoms, and about one-third of them suffer from major depression. It is the second most common disease in humans after heart disease. Howe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/486A61P25/24
CPCA61K36/486A61K2236/331A61K2236/333A61K2236/39A61K2236/53
Inventor 农志欢李冬梅曹斌韦桂宁苏华何飞曾宪彪卢文杰陆国寿黄周峰
Owner GUANGXI INST OF CHINESE MEDICINE & PHARMA SCI
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