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Traditional Chinese medicinal composition for preventing and treating acute mastitis of nursing sows

A technology for sucking sows and compositions, which is applied in the field of traditional Chinese medicine compositions, can solve problems affecting the growth performance of whole litter piglets, regurgitation, and reduced milk production of sows, so as to achieve no drug resistance, rapid onset, and The effect of promoting milk secretion

Inactive Publication Date: 2017-08-29
SHENYANG VICA ANIMAL HUSBANDRY TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, most domestic farmers use antibiotics combined with antipyretic and analgesic drugs for treatment, which treats the symptoms but not the root cause, and often causes milk regurgitation, and the milk production of sows is significantly reduced, which in turn affects the growth performance of the whole litter of piglets

Method used

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  • Traditional Chinese medicinal composition for preventing and treating acute mastitis of nursing sows

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Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0019] Specific embodiment 1 The proportioning of traditional Chinese medicine composition

[0020] Formula 1: Honeysuckle 15kg, Leulu 5kg, Prunella vulgaris 10kg, Dandelion 14kg, Boluohui 5kg, Astragalus 25kg, Angelica 8kg, Trichosanthes 8kg, Licorice 10kg.

[0021] Formula 2: Honeysuckle 5kg, Leulu 7kg, Prunella vulgaris 14kg, Dandelion 20kg, Boluohui 7kg, Astragalus 28kg, Angelica 7kg, Trichosanthes 5kg, Licorice 7kg.

[0022] Formula 3: Honeysuckle 10kg, Leulu 9kg, Prunella vulgaris 18kg, Dandelion 10kg, Boluohui 10kg, Astragalus 10kg, Angelica 15kg, Trichosanthes 9kg, Licorice 9kg.

[0023] Formula 4: Honeysuckle 8kg, Leulu 13kg, Prunella vulgaris 11kg, Dandelion 10kg, Bo Luohui 9kg, Astragalus 14kg, Angelica 15kg, Trichosanthes 12kg, Licorice 8kg.

[0024] Formula 5: Honeysuckle 12kg, Leulu 15kg, Prunella vulgaris 12kg, Dandelion 11kg, Boluohui 6kg, Astragalus 19kg, Angelica 5kg, Trichosanthes 15kg, Licorice 5kg.

specific Embodiment approach 2

[0025] Specific embodiment 2 Preparation of different dosage forms of traditional Chinese medicine composition

[0026] The preparation method of the powder: weigh various raw medicinal materials according to the formula ratio, pulverize them through an 80-mesh sieve with an ultrafine pulverizer, mix them evenly, and pot them to obtain the powder.

[0027] Oral liquid preparation method: remove impurities and wash, add 8 times, 6 times, and 6 times the volume of the total weight of medicinal materials, reflux extraction 3 times, the temperature is 100 ° C, each extraction time is 60 minutes, combine the three extracts and transfer into the concentration tank, and concentrated to the equivalent of 1g of crude drug per milliliter of liquid medicine. Fill and seal.

[0028] Preparation method of granules: remove impurities and wash, add 8 times, 6 times, and 6 times the volume of the total weight of medicinal materials, reflux extraction 3 times, the temperature is 100 ° C, and ...

specific Embodiment approach 3

[0030] Specific implementation mode 3: Pharmacodynamic research

[0031] In vitro antibacterial test (drug sensitive tablet method)

[0032] Test drug: Chinese medicine oral liquid prepared according to formula 1 in embodiment 1

[0033] Test strains: standard bacteria CVCC1882 third generation of Staphylococcus aureus slant culture on nutrient agar

[0034] Preparation of Drug Sensitive Tablets: Take Xinhua No. 1 qualitative filter paper and punch it into small circular paper pieces with a diameter of 6 mm. Take 50 pieces of round paper and put them into a clean and dry empty penicillin bottle, and wrap the mouth of the bottle with a single layer of kraft paper. After autoclaving at 120°C for 20 minutes, place it in a 37°C incubator or oven for several days to completely dry it.

[0035] Antibacterial drug paper sheet making: add 0.25 milliliters of Chinese medicine oral liquid prepared in example 1 in the above-mentioned penicillin bottle that contains 50 paper sheets, an...

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Abstract

The invention discloses a traditional Chinese medicinal composition for preventing and treating acute mastitis of nursing sows, which is a preparation prepared from the following medicinal materials in percentage by weight: 5%-15% of Lonicera japonica flowers, 5%-15% of Rhaponticum uniflorum, 10%-20% of Prunella vulgaris, 10%-20% of Herba Taraxaci, 5%-10% of Macleaya cordata, 10%-30% of Astragalus membranaceus, 5%-15% of Angelica sinensis, 5%-15% of Fructus Trichosanthis, and 5%-15% of Radix Glycyrrhizae. The traditional Chinese medicinal composition of the invention has the outstanding advantages of easily available raw materials, low cost, simple production process, and controllable quality. The traditional Chinese medicinal composition has rapid action on acute mastitis, the swelling is distinctly relieved after the composition is administrated for 24 hours, and is nearly cured after the composition is successively administrated for 3 days. The total effective rate is 100%, and the cure rate is up to 90% or higher. The traditional Chinese medicinal composition is used in clinical practice with no residues, no drug tolerance and no environmental pollution; and the composition can increase milk secretion of sows and enhance immunity of piglets.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for preventing and treating acute mastitis of lactating sows. Background technique [0002] Porcine acute mastitis is a common disease in lactating sows. Generally, one or more teats are sick at the same time, which seriously affects the development of pig industry, and the incidence rate is as high as 30-50%. The causes of the disease are many: 1. Mechanical damage, piglets biting the nipples while breastfeeding, or sagging breasts of multiparous sows rubbing against the farrowing bed. cocci, staphylococci, Escherichia coli and Pseudomonas aeruginosa). 3. Sows are supplemented with high-quality, juicy feed before and after farrowing, the milk secretion is vigorous, and the stagnation of breast milk causes acute mastitis. Affected breasts have different degrees of hyperemia (redness), swelling (enlargement, hardening), warm...

Claims

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Application Information

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IPC IPC(8): A61K36/66A61P15/14
CPCA61K36/232A61K36/28A61K36/288A61K36/355A61K36/428A61K36/481A61K36/484A61K36/536A61K36/66A61K2300/00
Inventor 许丹王方王洪礼
Owner SHENYANG VICA ANIMAL HUSBANDRY TECH
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