Echinocandin fungi residue and sludge mixing wet-type anaerobic digestion cooperated disposal method

An anaerobic digestion and echinocandin technology, which is applied to biological sludge treatment, pyrolysis treatment sludge, waste fuel, etc., can solve the problems of large equipment footprint, large resource consumption, and low treatment efficiency, and achieve Improve biochemical properties, improve nutrient ratio, and ensure activity

Active Publication Date: 2017-09-01
NANJING AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These methods generally have disadvantages such as large resource consumption, low processing efficiency, large odor, and large equipment footprint in engineering applications.
So far, there are no successful examples of modification and disposal of echinocandin residues at home and abroad

Method used

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  • Echinocandin fungi residue and sludge mixing wet-type anaerobic digestion cooperated disposal method
  • Echinocandin fungi residue and sludge mixing wet-type anaerobic digestion cooperated disposal method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] (1) Alkali-thermal modification of echinocandin bacteria residue

[0026] Get 2L of echinocandin bacterial residue (pH value 7.1, water content 97%, volatile solid VS 92.5%, crude protein 38.1%, crude fiber 8.91%, crude fat 2.01%) of certain biopharmaceutical factory; With 0.05g ( NaOH) / g(TS) ratio was added to NaOH, then treated in a 70°C water bath for 2h, cooled to room temperature, and set aside.

[0027] (2) thermal hydrolysis of sludge

[0028] Take 1L of sewage biochemical treatment sludge (pH value 6.75, water content 96.5%, VS 56.2%), put the sludge in a high-temperature cooking pot at 121°C for 30 minutes, cool to room temperature, and set aside.

[0029] (3) Mixing of bacteria residue and sludge

[0030] The echinocandin bacterial residue modified by step (1) and the sludge thermally hydrolyzed in step (2) are uniformly mixed at a volume ratio of 2:1 to obtain a mixed material of bacterial residue and sludge.

[0031] (4) Anaerobic digestion to produce bio...

Embodiment 2

[0045] (1) Alkali-thermal modification of echinocandin bacteria residue

[0046] Take 3L of echinocandin bacteria residue (pH value 7.3, water content 96%, VS 93.7%, crude protein 49.3%, crude fiber 1.79%, crude fat 5.23%) from a biopharmaceutical factory. Add NaOH at a ratio of 0.08g(NaOH) / g(TS), then treat in a water bath at 80°C for 1h, and cool to room temperature for use.

[0047] (2) thermal hydrolysis of sludge

[0048] Take 1L of sewage biochemical treatment sludge (pH value 6.5, water content 97.2%, VS 52%), and put the sludge in a high-temperature cooking pot at 150° C. for 15 minutes for hydrolysis. Cool to room temperature and set aside.

[0049] (3) Mixing of bacteria residue and sludge

[0050] The echinocandin slag modified by step (1) and the sludge subjected to thermal hydrolysis in step (2) are uniformly mixed at a volume ratio of 3:1 to obtain a mixed material of slag and sludge.

[0051] (4) Anaerobic digestion to produce biogas

[0052] Put 4L of mixe...

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PUM

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Abstract

The invention discloses an echinocandin fungi residue and sludge mixing wet process anaerobic digestion cooperated disposal method, which comprises the steps of performing alkali heat modification on echinocandin fungi residue; then, performing mixing wet-type anaerobic digestion on the modified fungi residue and the sludge to realize the cooperated disposal of two kinds of organic wastes. Through the alkali heat modification, the echinocandin fungi residue is subjected to fast cell breaking; cytoplasm is dissolved out; long-chain organic matters are hydrolyzed into short-chain organic matters; the biodegradability of the fungi residue is improved. In addition, the nutrition mixture ratio of the anaerobic digestion system is changed through the reasonable matching of the fungi residue and the sludge; the activity of methane bacteria is ensured; the anaerobic digestion speed and the gas yield are obviously improved. No echinocandin residue basically exists after the treatment is completed by the method; the prominent environment-friendly benefits and economic benefits are realized.

Description

technical field [0001] The invention belongs to the technical field of solid waste treatment, and relates to a method for harmless treatment of echinocandin slag, in particular to a method for co-processing of mixed wet anaerobic digestion of echinocandin slag and sludge. Background technique [0002] Echinocandin is a natural microbial product discovered in the 1970s. It is a new class of lipopeptide antifungal drugs. It has broad antibacterial spectrum, strong antibacterial effect, long half-life, few and mild adverse reactions, and is widely used in clinical practice. . According to statistics, the production of echinocandin source drugs in my country accounts for more than 70% of the world. However, in the process of biosynthesis and extraction of echinocandins, a type of hazardous waste—bacteria residue (classified as HW02 medical waste in the National Catalog of Hazardous Wastes) will be produced. The main components of echinocandin slag are mycelium, remaining mediu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P5/02C02F11/10C02F11/04
CPCC12P5/023C02F11/04C02F11/10Y02E50/30
Inventor 方迪白雪
Owner NANJING AGRICULTURAL UNIVERSITY
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